Phase 1 study of MEDI3902, an investigational anti–Pseudomonas aeruginosa PcrV and Psl bispecific human monoclonal antibody, in healthy adults
Ali, S.O., Yu, X.Q., Robbie, G.J., Wu, Y., Shoemaker, K., Yu, L., DiGiandomenico, A., Keller, A.E., Anude, C., Hernandez-Illas, M., Bellamy, T., Falloon, J., Dubovsky, F., Jafri, H.S.
Published in Clinical microbiology and infection (01.05.2019)
Published in Clinical microbiology and infection (01.05.2019)
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Pseudomonas aeruginosa PcrV and Psl, the Molecular Targets of Bispecific Antibody MEDI3902, Are Conserved Among Diverse Global Clinical Isolates
Tabor, D E, Oganesyan, V, Keller, A E, Yu, L, McLaughlin, R E, Song, E, Warrener, P, Rosenthal, K, Esser, M, Qi, Y, Ruzin, A, Stover, C K, DiGiandomenico, A
Published in The Journal of infectious diseases (05.11.2018)
Published in The Journal of infectious diseases (05.11.2018)
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7 Anti-Psl/PcrV bispecific monoclonal antibody potentiates in vitro and in vivo bacterial clearance of Pseudomonas aeruginosa from children with cystic fibrosis who failed tobramycin eradication therapy
Goldman, S., Kwong, K., Beauchamp, A., Waters, V., DiGiandomenico, A., Nguyen, D.
Published in Journal of cystic fibrosis (01.09.2024)
Published in Journal of cystic fibrosis (01.09.2024)
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538 Monoclonal antibodies targeting Psl and PcrV potentiate bacterial clearance of Pseudomonas aeruginosa from cystic fibrosis children who failed eradication therapy
Kwong, K., Beauchamp, A., Pereira-Kelton, C., Yau, Y., Howell, P., DiGiandomenico, A., Waters, V., Nguyen, D.
Published in Journal of cystic fibrosis (01.10.2022)
Published in Journal of cystic fibrosis (01.10.2022)
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570 Visualization of Pseudomonas aeruginosa biofilms in sputum of children with cystic fibrosis who fail eradication therapy
Morris, A., Yau, Y., Howell, P., Parsek, M., Hoffman, L., Nguyen, D., Rooney, A., Coburn, B., McDonald, N., DiGiandomenico, A., Wozniak, D., Waters, V.
Published in Journal of cystic fibrosis (01.10.2022)
Published in Journal of cystic fibrosis (01.10.2022)
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A95 ACUTE PNEUMONIA: CLINICAL STUDIES: Protective Activity Of Medi3902 For The Prevention Or Treatment Of Lethal Pneumonia And Bloodstream Infection Caused By Pseudomonas AerugINOSa In Rabbits
DiGiandomenico, A, Le, H, Pinheiro, M G, Le, V T M, Aguiar-Alves, F, Quetz, J, Tran, V G, Stover, C K, Diep, B
Published in American journal of respiratory and critical care medicine (01.01.2017)
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Published in American journal of respiratory and critical care medicine (01.01.2017)
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OP0331 A novel humanized effector-deficient fcyriia antibody inhibits immune complex mediated proinflammatory responses
Chen, B, Vousden, K, Turman, S, Sun, H, Wang, S, Vinall, L, Kemp, B, Kasturiangan, S, Grant, E, Hinrichs, MJ, Eck, S, DiGiandomenico, A, Xiong, X, Griffiths, J, Herbst, R, Close, D, Kolbeck, R, Sims, G
Published in Annals of the rheumatic diseases (01.06.2017)
Published in Annals of the rheumatic diseases (01.06.2017)
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B101 ACUTE LUNG INJURY AND INFLAMMATION: Staphylococcus Aureus Alpha-Toxin Potentiates Pseudomonas AerugINOSa Infection In A Murine Pneumonia Model
Hilliard, J J, Jones-Nelson, O, Cohen, T S, Tkaczyk, C, DiGiandomenico, A, Stover, C K, Sellman, B
Published in American journal of respiratory and critical care medicine (01.01.2015)
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Published in American journal of respiratory and critical care medicine (01.01.2015)
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D24 GRAM NEGATIVE PNEUMONIAS: FROM BENCH TO BEDSIDE: Dna-Delivery Of Monospecific And Bispecific Monoclonal Antibodies Targeting Pseudomonas AerugINOSa Protect Mice From Lethal Pneumonia
DiGiandomenico, A, Patel, A, Smith, T, Keller, A, Elliot, S T C, Wachter, L, McAuliffe, J, Ramos, S, Broderick, K, Yan, J, Khan, A, Park, D H, Wise, M, Karuppiah, M, Flingai, S, Humeau, L, Sardesai, N, Stover, C, Weiner, D
Published in American journal of respiratory and critical care medicine (01.01.2016)
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Published in American journal of respiratory and critical care medicine (01.01.2016)
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C105 ENVISIONING AND TESTING NEW THERAPEUTIC APPROACHES TO PNEUMONIA: Controlling Pseudomonas AerugINOSa Infections Using A Novel Multifunction Antibody Design
DiGiandomenico, A, Keller, A, Gao, C, Camara, M M, Rainey, G J, Bonnell, J, Warrener, P, Flemming, R, Bezabeh, B, Dimasi, N, Hilliard, J, Datta, V, Zhao, W, Yu, X-Q, Suzich, J, Stover, K
Published in American journal of respiratory and critical care medicine (01.01.2014)
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Published in American journal of respiratory and critical care medicine (01.01.2014)
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Oral Vaccination of BALB/c Mice with Salmonella enterica Serovar Typhimurium Expressing Pseudomonas aeruginosa O Antigen Promotes Increased Survival in an Acute Fatal Pneumonia Model
DIGIANDOMENICO, Antonio, RAO, Jayasimha, GOLDBERG, Joanna B
Published in Infection and Immunity (01.12.2004)
Published in Infection and Immunity (01.12.2004)
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Glycosylation of Pseudomonas aeruginosa 1244 pilin: glycan substrate specificity
DiGiandomenico, Antonio, Matewish, Mauricia J., Bisaillon, Amy, Stehle, John R., Lam, Joseph S., Castric, Peter
Published in Molecular microbiology (01.10.2002)
Published in Molecular microbiology (01.10.2002)
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Anti-PcrV and Psl bispecifics for treatment of bronchiectasis
OSTRIDGE, KRISTOFFER, SELLMAN, BRET, HUGHES, RODNEY JASON, BRAILSFORD, WAYNE, DIGIANDOMENICO, ANTONIO
Year of Publication 01.05.2024
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Year of Publication 01.05.2024
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METHOD FOR PREVENTING OR TREATING NOSOCOMIAL PNEUMONIA
DIGIANDOMENICO, Antonio, MCCARTHY, Michael, STOVER, Charles, K, BISHOP, Brian, JAFRI, Hasan, YU, Xiang-Qing
Year of Publication 18.10.2019
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Year of Publication 18.10.2019
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METHOD FOR PREVENTING OR TREATING NOSOCOMIAL PNEUMONIA
DIGIANDOMENICO, Antonio, MCCARTHY, Michael, STOVER, Charles, K, BISHOP, Brian, JAFRI, Hasan, YU, Xiang-Qing
Year of Publication 26.07.2019
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Year of Publication 26.07.2019
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ANTI-PSEUDOMONAS PSL BINDING MOLECULES AND USES THEREOF
SELLMAN, Bret, DIGIANDOMENICO, Antonio, MINTER, Ralph, TOMICH, Mladen, GUILLARD, Sandrine, WARRENER, Paul G, RUST, Steven, STOVER, Charles K
Year of Publication 18.10.2019
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Year of Publication 18.10.2019
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METHOD FOR PREVENTING OR TREATING NOSOCOMIAL PNEUMONIA
YU XIANG-QING, JAFRI HASAN, DIGIANDOMENICO ANTHONY, BISHOP BRIAN, STOVER CHARLES K, MCCARTHY MICHAEL
Year of Publication 03.08.2018
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Year of Publication 03.08.2018
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Anti-pseudomonas Psl binding molecules and uses thereof
TOMICH, MLADEN, SELLMAN, BRET, RUST, STEVEN, GUILLARD, SANDRINE, MINTER, RALPH, DIGIANDOMENICO, ANTONIO, STOVER, CHARLES, K, WARRENER, PAUL, G
Year of Publication 06.08.2014
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Year of Publication 06.08.2014
Patent