Pharmacokinetics and Pharmacodynamics of Subcutaneous Sarilumab and Intravenous Tocilizumab Following Single‐Dose Administration in Patients With Active Rheumatoid Arthritis on Stable Methotrexate
Paccaly, Anne J., Kovalenko, Pavel, Parrino, Janie, Boyapati, Anita, Xu, Christine, Hoogstraten, Hubert, Ishii, Tomonori, Davis, John D., DiCioccio, A. Thomas
Published in Journal of clinical pharmacology (01.01.2021)
Published in Journal of clinical pharmacology (01.01.2021)
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Population Pharmacokinetic Analysis of Alirocumab in Healthy Volunteers or Hypercholesterolemic Subjects Using a Michaelis–Menten Approximation of a Target-Mediated Drug Disposition Model—Support for a Biologics License Application Submission: Part I
Martinez, Jean-Marie, Brunet, Aurélie, Hurbin, Fabrice, DiCioccio, A. Thomas, Rauch, Clémence, Fabre, David
Published in Clinical pharmacokinetics (01.01.2019)
Published in Clinical pharmacokinetics (01.01.2019)
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Efficacy and Safety of Sarilumab in Hospitalized Patients With Coronavirus Disease 2019: A Randomized Clinical Trial
Sivapalasingam, Sumathi, Lederer, David J, Bhore, Rafia, Hajizadeh, Negin, Criner, Gerard, Hosain, Romana, Mahmood, Adnan, Giannelou, Angeliki, Somersan-Karakaya, Selin, O’Brien, Meagan P, Boyapati, Anita, Parrino, Janie, Musser, Bret J, Labriola-Tompkins, Emily, Ramesh, Divya, Purcell, Lisa A, Gulabani, Daya, Kampman, Wendy, Waldron, Alpana, Ng Gong, Michelle, Saggar, Suraj, Sperber, Steven J, Menon, Vidya, Stein, David K, Sobieszczyk, Magdalena E, Park, William, Aberg, Judith A, Brown, Samuel M, Kosmicki, Jack A, Horowitz, Julie E, Ferreira, Manuel A, Baras, Aris, Kowal, Bari, Thomas DiCioccio, A, Akinlade, Bolanle, Nivens, Michael C, Braunstein, Ned, Herman, Gary A, Yancopoulos, George D, Weinreich, David M
Published in Clinical infectious diseases (24.08.2022)
Published in Clinical infectious diseases (24.08.2022)
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A drug‐disease model for predicting survival in an Ebola outbreak
Toroghi, Masood Khaksar, Al‐Huniti, Nidal, Davis, John D., DiCioccio, A. Thomas, Rippley, Ronda, Baum, Alina, Kyratsous, Christos A., Sivapalasingam, Sumathi, Kantrowitz, Joel, Kamal, Mohamed A.
Published in Clinical and translational science (01.10.2022)
Published in Clinical and translational science (01.10.2022)
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Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Dupilumab in Healthy Adult Subjects
Li, Zhaoyang, Radin, Allen, Li, Meng, Hamilton, Jennifer D., Kajiwara, Miyuki, Davis, John D., Takahashi, Yoshinori, Hasegawa, Setsuo, Ming, Jeffrey E., DiCioccio, A. Thomas, Li, Yongtao, Kovalenko, Pavel, Lu, Qiang, Ortemann‐Renon, Catherine, Ardeleanu, Marius, Swanson, Brian N.
Published in Clinical pharmacology in drug development (01.08.2020)
Published in Clinical pharmacology in drug development (01.08.2020)
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Immunogenicity of dupilumab in adult and pediatric patients with atopic dermatitis
Kamal, Mohamed A, Kosloski, Matthew P, Lai, Ching-Ha, Partridge, Michael A, Rajadhyaksha, Manoj, Kanamaluru, Vanaja, Bansal, Ashish, Shabbir, Arsalan, Shumel, Brad, Ardeleanu, Marius, Richards, Susan M, Yan, Hong, Xu, Christine R, Rodríguez-Marco, Ainara, Xiao, Jing, Khokhar, Faisal A, Gherardi, Guy, Babilonia, Elisa, Maloney, Jennifer, Mortensen, Eric, Akinlade, Bolanle, Braunstein, Ned, Stahl, Neil, Torri, Albert, Davis, John D, DiCioccio, A Thomas
Published in Frontiers in immunology (11.11.2024)
Published in Frontiers in immunology (11.11.2024)
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Assessing the safety and pharmacokinetics of casirivimab and imdevimab (CAS+IMD) in a cohort of pregnant outpatients with COVID-19: results from an adaptive, multicentre, randomised, double-blind, phase 1/2/3 study
Norton, Thomas D, Thakur, Mazhar, Ganguly, Samit, Ali, Shazia, Chao, Jesse, Waldron, Alpana, Xiao, Jing, Patel, Yogesh, Turner, Kenneth C, Davis, John D, Irvin, Susan C, Pan, Cynthia, Atmodjo-Watkins, Dominique, Hooper, Andrea T, Hamilton, Jennifer D, Subramaniam, Danise, Bocchini, Joseph A, Kowal, Bari, DiCioccio, A. Thomas, Bhore, Rafia, Geba, Gregory P, Cox, Edward, Braunstein, Ned, Dakin, Paula, Herman, Gary A
Published in BMJ open (08.10.2024)
Published in BMJ open (08.10.2024)
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Translational findings for odronextamab: From preclinical research to a first‐in‐human study in patients with CD20+ B‐cell malignancies
Zhu, Min, Olson, Kara, Kirshner, Jessica R., Khaksar Toroghi, Masood, Yan, Hong, Haber, Lauric, Meagher, Craig, Flink, Dina M., Ambati, Srikanth R., Davis, John D., DiCioccio, A. Thomas, Smith, Eric J., Retter, Marc W.
Published in Clinical and translational science (01.04.2022)
Published in Clinical and translational science (01.04.2022)
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Journal Article
Relationship Between Low‐Density Lipoprotein Cholesterol, Free Proprotein Convertase Subtilisin/Kexin Type 9, and Alirocumab Levels After Different Lipid‐Lowering Strategies
Rey, Jacques, Poitiers, Franck, Paehler, Tobias, Brunet, Aurélie, DiCioccio, A. Thomas, Cannon, Christopher P., Surks, Howard K., Pinquier, Jean‐Louis, Hanotin, Corinne, Sasiela, William J.
Published in Journal of the American Heart Association (01.06.2016)
Published in Journal of the American Heart Association (01.06.2016)
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Population Pharmacodynamic Model of Neutrophil Margination and Tolerance to Describe Effect of Sarilumab on Absolute Neutrophil Count in Patients with Rheumatoid Arthritis
Kovalenko, Pavel, Paccaly, Anne, Boyapati, Anita, Xu, Christine, St John, Gregory, Nivens, Michael C., Davis, John D., Rippley, Ronda, DiCioccio, A. Thomas
Published in CPT: pharmacometrics and systems pharmacology (01.07.2020)
Published in CPT: pharmacometrics and systems pharmacology (01.07.2020)
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Discovery of 3-[(4,5,7-Trifluorobenzothiazol-2-yl)methyl]indole-N-acetic Acid (Lidorestat) and Congeners as Highly Potent and Selective Inhibitors of Aldose Reductase for Treatment of Chronic Diabetic Complications
Van Zandt, Michael C, Jones, Michael L, Gunn, David E, Geraci, Leo S, Jones, J. Howard, Sawicki, Diane R, Sredy, Janet, Jacot, Jorge L, DiCioccio, A. Thomas, Petrova, Tatiana, Mitschler, Andre, Podjarny, Alberto D
Published in Journal of medicinal chemistry (05.05.2005)
Published in Journal of medicinal chemistry (05.05.2005)
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REGEN-COV Antibody Combination and Outcomes in Outpatients with Covid-19
Weinreich, David M, Sivapalasingam, Sumathi, Norton, Thomas, Ali, Shazia, Gao, Haitao, Bhore, Rafia, Xiao, Jing, Hooper, Andrea T, Hamilton, Jennifer D, Musser, Bret J, Rofail, Diana, Hussein, Mohamed, Im, Joseph, Atmodjo, Dominique Y, Perry, Christina, Pan, Cynthia, Mahmood, Adnan, Hosain, Romana, Davis, John D, Turner, Kenneth C, Baum, Alina, Kyratsous, Christos A, Kim, Yunji, Cook, Amanda, Kampman, Wendy, Roque-Guerrero, Lilia, Acloque, Gerard, Aazami, Hessam, Cannon, Kevin, Simón-Campos, J. Abraham, Bocchini, Joseph A, Kowal, Bari, DiCioccio, A. Thomas, Soo, Yuhwen, Geba, Gregory P, Stahl, Neil, Lipsich, Leah, Braunstein, Ned, Herman, Gary, Yancopoulos, George D
Published in New England Journal of Medicine (02.12.2021)
Published in New England Journal of Medicine (02.12.2021)
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Subcutaneous REGEN-COV Antibody Combination to Prevent Covid-19
O’Brien, Meagan P, Forleo-Neto, Eduardo, Musser, Bret J, Isa, Flonza, Chan, Kuo-Chen, Sarkar, Neena, Bar, Katharine J, Barnabas, Ruanne V, Barouch, Dan H, Cohen, Myron S, Hurt, Christopher B, Burwen, Dale R, Marovich, Mary A, Hou, Peijie, Heirman, Ingeborg, Davis, John D, Turner, Kenneth C, Ramesh, Divya, Mahmood, Adnan, Hooper, Andrea T, Hamilton, Jennifer D, Kim, Yunji, Purcell, Lisa A, Baum, Alina, Kyratsous, Christos A, Krainson, James, Perez-Perez, Richard, Mohseni, Rizwana, Kowal, Bari, DiCioccio, A. Thomas, Stahl, Neil, Lipsich, Leah, Braunstein, Ned, Herman, Gary, Yancopoulos, George D, Weinreich, David M
Published in New England Journal of Medicine (23.09.2021)
Published in New England Journal of Medicine (23.09.2021)
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Exhaled Nitric Oxide (FeNO) and T-Helper 2 Cell Biomarkers: Can They Predict Treatment Response To Dupilumab, An IL-4Rα Antibody, In An Eosinophilic Asthma Population?
Swanson, Brian N., PhD, Wang, Lin, PhD, Ming, Jeffrey, MD, Hamilton, Jennifer D., PhD, Teper, Ariel, MD, Dicioccio, Thomas, PhD, Li, Yongtao, PhD, Graham, Neil, Dr, Pirozzi, Gianluca, Dr, Wenzel, Sally E., MD, FAAAAI
Published in Journal of allergy and clinical immunology (01.02.2014)
Published in Journal of allergy and clinical immunology (01.02.2014)
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Effect of Subcutaneous Casirivimab and Imdevimab Antibody Combination vs Placebo on Development of Symptomatic COVID-19 in Early Asymptomatic SARS-CoV-2 Infection: A Randomized Clinical Trial
O’Brien, Meagan P, Forleo-Neto, Eduardo, Sarkar, Neena, Isa, Flonza, Hou, Peijie, Chan, Kuo-Chen, Musser, Bret J, Bar, Katharine J, Barnabas, Ruanne V, Barouch, Dan H, Cohen, Myron S, Hurt, Christopher B, Burwen, Dale R, Marovich, Mary A, Brown, Elizabeth R, Heirman, Ingeborg, Davis, John D, Turner, Kenneth C, Ramesh, Divya, Mahmood, Adnan, Hooper, Andrea T, Hamilton, Jennifer D, Kim, Yunji, Purcell, Lisa A, Baum, Alina, Kyratsous, Christos A, Krainson, James, Perez-Perez, Richard, Mohseni, Rizwana, Kowal, Bari, DiCioccio, A. Thomas, Geba, Gregory P, Stahl, Neil, Lipsich, Leah, Braunstein, Ned, Herman, Gary, Yancopoulos, George D, Weinreich, David M
Published in JAMA : the journal of the American Medical Association (01.02.2022)
Published in JAMA : the journal of the American Medical Association (01.02.2022)
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Population Pharmacokinetics of Casirivimab and Imdevimab in Pediatric and Adult Non-Infected Individuals, Pediatric and Adult Ambulatory or Hospitalized Patients or Household Contacts of Patients Infected with SARS-COV-2
Lin, Kuan-Ju, Turner, Kenneth C., Rosario, Maria, Harnisch, Lutz O., Davis, John D., DiCioccio, A. Thomas
Published in Pharmaceutical research (01.10.2024)
Published in Pharmaceutical research (01.10.2024)
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Evaluation of Potential Disease‐Mediated Drug–Drug Interaction in Patients With Moderate‐to‐Severe Atopic Dermatitis Receiving Dupilumab
Davis, John D., Bansal, Ashish, Hassman, David, Akinlade, Bolanle, Li, Meng, Li, Zhaoyang, Swanson, Brian, Hamilton, Jennifer D., DiCioccio, A. Thomas
Published in Clinical pharmacology and therapeutics (01.12.2018)
Published in Clinical pharmacology and therapeutics (01.12.2018)
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Journal Article
Casirivimab and Imdevimab for the Treatment of Hospitalized Patients With COVID-19
Somersan-Karakaya, Selin, Mylonakis, Eleftherios, Menon, Vidya P, Wells, Jason C, Ali, Shazia, Sivapalasingam, Sumathi, Sun, Yiping, Bhore, Rafia, Mei, Jingning, Miller, Jutta, Cupelli, Lisa, Forleo-Neto, Eduardo, Hooper, Andrea T, Hamilton, Jennifer D, Pan, Cynthia, Pham, Viet, Zhao, Yuming, Hosain, Romana, Mahmood, Adnan, Davis, John D, Turner, Kenneth C, Kim, Yunji, Cook, Amanda, Kowal, Bari, Soo, Yuhwen, DiCioccio, A Thomas, Geba, Gregory P, Stahl, Neil, Lipsich, Leah, Braunstein, Ned, Herman, Gary A, Yancopoulos, George D, Weinreich, David M
Published in The Journal of infectious diseases (28.12.2022)
Published in The Journal of infectious diseases (28.12.2022)
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Journal Article
Regulation of Plasma Fructose and Mortality in Mice by the Aldose Reductase Inhibitor Lidorestat
Noh, Hye-Lim, Hu, Yunying, Park, Tae-Sik, DiCioccio, Thomas, Nichols, Andrew J, Okajima, Kazue, Homma, Shunichi, Goldberg, Ira J
Published in The Journal of pharmacology and experimental therapeutics (01.02.2009)
Published in The Journal of pharmacology and experimental therapeutics (01.02.2009)
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