Phage Selection of Cyclic Peptides for Application in Research and Drug Development
Deyle, Kaycie, Kong, Xu-Dong, Heinis, Christian
Published in Accounts of chemical research (15.08.2017)
Published in Accounts of chemical research (15.08.2017)
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Cyclic peptide FXII inhibitor provides safe anticoagulation in a thrombosis model and in artificial lungs
Wilbs, Jonas, Kong, Xu-Dong, Middendorp, Simon J., Prince, Raja, Cooke, Alida, Demarest, Caitlin T., Abdelhafez, Mai M., Roberts, Kalliope, Umei, Nao, Gonschorek, Patrick, Lamers, Christina, Deyle, Kaycie, Rieben, Robert, Cook, Keith E., Angelillo-Scherrer, Anne, Heinis, Christian
Published in Nature communications (04.08.2020)
Published in Nature communications (04.08.2020)
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Epitope Targeting of Tertiary Protein Structure Enables Target-Guided Synthesis of a Potent In-Cell Inhibitor of Botulinum Neurotoxin
Farrow, Blake, Wong, Michelle, Malette, Jacquie, Lai, Bert, Deyle, Kaycie M., Das, Samir, Nag, Arundhati, Agnew, Heather D., Heath, James R.
Published in Angewandte Chemie International Edition (08.06.2015)
Published in Angewandte Chemie International Edition (08.06.2015)
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A Chemically Synthesized Capture Agent Enables the Selective, Sensitive, and Robust Electrochemical Detection of Anthrax Protective Antigen
Farrow, Blake, Hong, Sung A, Romero, Errika C, Lai, Bert, Coppock, Matthew B, Deyle, Kaycie M, Finch, Amethist S, Stratis-Cullum, Dimitra N, Agnew, Heather D, Yang, Sung, Heath, James R
Published in ACS nano (22.10.2013)
Published in ACS nano (22.10.2013)
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Macrocycle synthesis strategy based on step-wise "adding and reacting" three components enables screening of large combinatorial libraries
Mothukuri, Ganesh K, Kale, Sangram S, Stenbratt, Carl L, Zorzi, Alessandro, Vesin, Jonathan, Bortoli Chapalay, Julien, Deyle, Kaycie, Turcatti, Gerardo, Cendron, Laura, Angelini, Alessandro, Heinis, Christian
Published in Chemical science (Cambridge) (14.08.2020)
Published in Chemical science (Cambridge) (14.08.2020)
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A protein-targeting strategy used to develop a selective inhibitor of the E17K point mutation in the PH domain of Akt1
Deyle, Kaycie M., Farrow, Blake, Qiao Hee, Ying, Work, Jeremy, Wong, Michelle, Lai, Bert, Umeda, Aiko, Millward, Steven W., Nag, Arundhati, Das, Samir, Heath, James R.
Published in Nature chemistry (01.05.2015)
Published in Nature chemistry (01.05.2015)
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A Chemical Epitope-Targeting Strategy for Protein Capture Agents: The Serine 474 Epitope of the Kinase Akt2
Nag, Arundhati, Das, Samir, Yu, Mary Beth, Deyle, Kaycie M., Millward, Steven W., Heath, James R.
Published in Angewandte Chemie International Edition (23.12.2013)
Published in Angewandte Chemie International Edition (23.12.2013)
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A cocktail of thermally stable, chemically synthesized capture agents for the efficient detection of anti-gp41 antibodies from human sera
Pfeilsticker, Jessica A, Umeda, Aiko, Farrow, Blake, Hsueh, Connie L, Deyle, Kaycie M, Kim, Jocelyn T, Lai, Bert T, Heath, James R
Published in PloS one (07.10.2013)
Published in PloS one (07.10.2013)
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A General Synthetic Approach for Designing Epitope Targeted Macrocyclic Peptide Ligands
Das, Samir, Nag, Arundhati, Liang, JingXin, Bunck, David N., Umeda, Aiko, Farrow, Blake, Coppock, Matthew B., Sarkes, Deborah A., Finch, Amethist S., Agnew, Heather D., Pitram, Suresh, Lai, Bert, Yu, Mary Beth, Museth, A. Katrine, Deyle, Kaycie M., Lepe, Bianca, Rodriguez-Rivera, Frances P., McCarthy, Amy, Alvarez-Villalonga, Belen, Chen, Ann, Heath, John, Stratis-Cullum, Dimitra N., Heath, James R.
Published in Angewandte Chemie International Edition (02.11.2015)
Published in Angewandte Chemie International Edition (02.11.2015)
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Corrigendum: Epitope Targeting of Tertiary Protein Structure Enables Target‐Guided Synthesis of a Potent In‐Cell Inhibitor of Botulinum Neurotoxin
Farrow, Blake, Wong, Michelle, Malette, Jacquie, Lai, Bert, Deyle, Kaycie M., Das, Samir, Nag, Arundhati, Agnew, Heather D., Heath, James R.
Published in Angewandte Chemie International Edition (05.02.2018)
Published in Angewandte Chemie International Edition (05.02.2018)
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Iterative in Situ Click Chemistry Assembles a Branched Capture Agent and Allosteric Inhibitor for Akt1
Millward, Steven W, Henning, Ryan K, Kwong, Gabriel A, Pitram, Suresh, Agnew, Heather D, Deyle, Kaycie M, Nag, Arundhati, Hein, Jason, Lee, Su Seong, Lim, Jaehong, Pfeilsticker, Jessica A, Sharpless, K. Barry, Heath, James R
Published in Journal of the American Chemical Society (16.11.2011)
Published in Journal of the American Chemical Society (16.11.2011)
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Correction to A Chemically Synthesized Capture Agent Enables the Selective, Sensitive, and Robust Electrochemical Detection of Anthrax Protective Antigen
Farrow, Blake, Hong, Sung A, Romero, Errika C, Lai, Bert, Coppock, Matthew B, Deyle, Kaycie M, Finch, Amethist S, Stratis-Cullum, Dimitra N, Agnew, Heather D, Yang, Sung, Heath, James R
Published in ACS nano (22.05.2018)
Published in ACS nano (22.05.2018)
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Cyclic peptide therapeutics: past, present and future
Zorzi, Alessandro, Deyle, Kaycie, Heinis, Christian
Published in Current opinion in chemical biology (01.06.2017)
Published in Current opinion in chemical biology (01.06.2017)
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Berichtigung: Epitope Targeting of Tertiary Protein Structure Enables Target‐Guided Synthesis of a Potent In‐Cell Inhibitor of Botulinum Neurotoxin
Farrow, Blake, Wong, Michelle, Malette, Jacquie, Lai, Bert, Deyle, Kaycie M., Das, Samir, Nag, Arundhati, Agnew, Heather D., Heath, James R.
Published in Angewandte Chemie (05.02.2018)
Published in Angewandte Chemie (05.02.2018)
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Journal Article
Epitope Targeting of Tertiary Protein Structure Enables Target-Guided Synthesis of a Potent In-Cell Inhibitor of Botulinum Neurotoxin
Farrow, Blake, Wong, Michelle, Malette, Jacquie, Lai, Bert, Deyle, Kaycie M., Das, Samir, Nag, Arundhati, Agnew, Heather D., Heath, James R.
Published in Angewandte Chemie (08.06.2015)
Published in Angewandte Chemie (08.06.2015)
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Journal Article
A General Synthetic Approach for Designing Epitope Targeted Macrocyclic Peptide Ligands
Das, Samir, Nag, Arundhati, Liang, JingXin, Bunck, David N., Umeda, Aiko, Farrow, Blake, Coppock, Matthew B., Sarkes, Deborah A., Finch, Amethist S., Agnew, Heather D., Pitram, Suresh, Lai, Bert, Yu, Mary Beth, Museth, A. Katrine, Deyle, Kaycie M., Lepe, Bianca, Rodriguez-Rivera, Frances P., McCarthy, Amy, Alvarez-Villalonga, Belen, Chen, Ann, Heath, John, Stratis-Cullum, Dimitra N., Heath, James R.
Published in Angewandte Chemie (02.11.2015)
Published in Angewandte Chemie (02.11.2015)
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Journal Article
Cyclization of peptides with two chemical bridges affords large scaffold diversities
Kale, Sangram S., Villequey, Camille, Kong, Xu-Dong, Zorzi, Alessandro, Deyle, Kaycie, Heinis, Christian
Published in Nature chemistry (01.07.2018)
Published in Nature chemistry (01.07.2018)
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