Structural Insight into HIV-1 Restriction by MxB
Fribourgh, Jennifer L., Nguyen, Henry C., Matreyek, Kenneth A., Alvarez, Frances Joan D., Summers, Brady J., Dewdney, Tamaria G., Aiken, Christopher, Zhang, Peijun, Engelman, Alan, Xiong, Yong
Published in Cell host & microbe (12.11.2014)
Published in Cell host & microbe (12.11.2014)
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The higher barrier of darunavir and tipranavir resistance for HIV-1 protease
Wang, Yong, Liu, Zhigang, Brunzelle, Joseph S., Kovari, Iulia A., Dewdney, Tamaria G., Reiter, Samuel J., Kovari, Ladislau C.
Published in Biochemical and biophysical research communications (09.09.2011)
Published in Biochemical and biophysical research communications (09.09.2011)
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Cryo-EM reveals a novel octameric integrase structure for betaretroviral intasome function
Ballandras-Colas, Allison, Brown, Monica, Cook, Nicola J., Dewdney, Tamaria G., Demeler, Borries, Cherepanov, Peter, Lyumkis, Dmitry, Engelman, Alan N.
Published in Nature (London) (18.02.2016)
Published in Nature (London) (18.02.2016)
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The L33F darunavir resistance mutation acts as a molecular anchor reducing the flexibility of the HIV-1 protease 30s and 80s loops
Kuiper, Benjamin D, Keusch, Bradley J, Dewdney, Tamaria G, Chordia, Poorvi, Ross, Kyla, Brunzelle, Joseph S, Kovari, Iulia A, MacArthur, Rodger, Salimnia, Hossein, Kovari, Ladislau C
Published in Biochemistry and biophysics reports (01.07.2015)
Published in Biochemistry and biophysics reports (01.07.2015)
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Higher Desolvation Energy Reduces Molecular Recognition in Multi-Drug Resistant HIV-1 Protease
Wang, Yong, Dewdney, Tamaria G, Liu, Zhigang, Reiter, Samuel J, Brunzelle, Joseph S, Kovari, Iulia A, Kovari, Ladislau C
Published in Biology (Basel, Switzerland) (31.05.2012)
Published in Biology (Basel, Switzerland) (31.05.2012)
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Reduced HIV-1 integrase flexibility as a mechanism for raltegravir resistance
Dewdney, Tamaria G., Wang, Yong, Kovari, Iulia A., Reiter, Samuel J., Kovari, Ladislau C.
Published in Journal of structural biology (01.11.2013)
Published in Journal of structural biology (01.11.2013)
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Conserved hydrogen bonds and water molecules in MDR HIV-1 protease substrate complexes
Liu, Zhigang, Wang, Yong, Yedidi, Ravikiran S., Dewdney, Tamaria G., Reiter, Samuel J., Brunzelle, Joseph S., Kovari, Iulia A., Kovari, Ladislau C.
Published in Biochemical and biophysical research communications (18.01.2013)
Published in Biochemical and biophysical research communications (18.01.2013)
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Crystallographic study of multi-drug resistant HIV-1 protease lopinavir complex: Mechanism of drug recognition and resistance
Liu, Zhigang, Yedidi, Ravikiran S., Wang, Yong, Dewdney, Tamaria G., Reiter, Samuel J., Brunzelle, Joseph S., Kovari, Iulia A., Kovari, Ladislau C.
Published in Biochemical and biophysical research communications (26.07.2013)
Published in Biochemical and biophysical research communications (26.07.2013)
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Insights into the mechanism of drug resistance: X-ray structure analysis of multi-drug resistant HIV-1 protease ritonavir complex
Liu, Zhigang, Yedidi, Ravikiran S., Wang, Yong, Dewdney, Tamaria G., Reiter, Samuel J., Brunzelle, Joseph S., Kovari, Iulia A., Kovari, Ladislau C.
Published in Biochemical and biophysical research communications (08.02.2013)
Published in Biochemical and biophysical research communications (08.02.2013)
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Ligand modifications to reduce the relative resistance of multi-drug resistant HIV-1 protease
Dewdney, Tamaria G., Wang, Yong, Liu, Zhigang, Sharma, Shiv K., Reiter, Samuel J., Brunzelle, Joseph S., Kovari, Iulia A., Woster, Patrick M., Kovari, Ladislau C.
Published in Bioorganic & medicinal chemistry (01.12.2013)
Published in Bioorganic & medicinal chemistry (01.12.2013)
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Journal Article
Cryo-EM reveals a novel octameric integrase structure for β-retroviral intasome function
Ballandras-Colas, Allison, Brown, Monica, Cook, Nicola J., Dewdney, Tamaria G., Demeler, Borries, Cherepanov, Peter, Lyumkis, Dmitry, Engelman, Alan N.
Published in Nature (London) (18.02.2016)
Published in Nature (London) (18.02.2016)
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The role of mutations at codons 32, 47, 54, and 90 in HIV-1 protease flap dynamics
Chordia, Poorvi, Dewdney, Tamaria G, Keusch, Bradley, Kuiper, Benjamin D, Ross, Kyla, Kovari, Iulia A, MacArthur, Rodger, Salimnia, Hossein, Kovari, Ladislau C
Published in Discoveries (Craiova, Romania) (31.12.2014)
Published in Discoveries (Craiova, Romania) (31.12.2014)
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Journal Article
The L33F darunavir resistance mutation acts as a molecular anchor reducing the flexibility of the HIV-1 protease 30s and 80s loops
Kuiper, Benjamin D., Keusch, Bradley J., Dewdney, Tamaria G., Chordia, Poorvi, Ross, Kyla, Brunzelle, Joseph S., Kovari, Iulia A., MacArthur, Rodger, Salimnia, Hossein, Kovari, Ladislau C.
Published in Biochemistry and biophysics reports (01.07.2015)
Published in Biochemistry and biophysics reports (01.07.2015)
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