Defective DNA damage repair leads to frequent catastrophic genomic events in murine and human tumors
Ratnaparkhe, Manasi, Wong, John K. L., Wei, Pei-Chi, Hlevnjak, Mario, Kolb, Thorsten, Simovic, Milena, Haag, Daniel, Paul, Yashna, Devens, Frauke, Northcott, Paul, Jones, David T. W., Kool, Marcel, Jauch, Anna, Pastorczak, Agata, Mlynarski, Wojciech, Korshunov, Andrey, Kumar, Rajiv, Downing, Susanna M., Pfister, Stefan M., Zapatka, Marc, McKinnon, Peter J., Alt, Frederick W., Lichter, Peter, Ernst, Aurélie
Published in Nature communications (12.11.2018)
Published in Nature communications (12.11.2018)
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Supratentorial primitive neuroectodermal tumors of the central nervous system frequently harbor deletions of the CDKN2A locus and other genomic aberrations distinct from medulloblastomas
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Published in Biomarkers (01.03.2011)
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Published in Cancer research (Chicago, Ill.) (15.11.2020)
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A synergistic interaction between HDAC‐ and PARP inhibitors in childhood tumors with chromothripsis
Khalid, Umar, Simovic, Milena, Hammann, Linda A., Iskar, Murat, Wong, John K. L., Kumar, Rithu, Jugold, Manfred, Sill, Martin, Bolkestein, Michiel, Kolb, Thorsten, Hergt, Michaela, Devens, Frauke, Ecker, Jonas, Kool, Marcel, Milde, Till, Westermann, Frank, Benner, Axel, Lewis, Joe, Dietrich, Sascha, Pfister, Stefan M., Lichter, Peter, Zapatka, Marc, Ernst, Aurélie
Published in International journal of cancer (15.08.2022)
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A versatile system to introduce clusters of genomic double‐strand breaks in large cell populations
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Published in Genes chromosomes & cancer (01.05.2021)
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Published in Experimental cell research (15.10.2018)
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Published in International journal of cancer (15.06.2016)
Published in International journal of cancer (15.06.2016)
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Abstract 3496: Defective DNA damage repair leads to frequent catastrophic genomic events in murine and human tumors
Ratnaparkhe, Manasi, Wong, John K., Wei, Pei-Chi, Hlevnjak, Mario, Kolb, Thorsten, Simovic, Milena, Haag, Daniel, Paul, Yashna, Devens, Frauke, Northcott, Paul, Jones, David T., Kool, Marcel, Jauch, Anna, Pastorczak, Agata, Mlynarski, Wojciech, Korshunov, Andrey, Kumar, Rajiv, Downing, Susanna M., Pfister, Stefan M., Zapatka, Marc, McKinnon, Peter J., Alt, Frederick W., Lichter, Peter, Ernst, Aurelie
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Overexpression of the far upstream element binding protein 1 in hepatocellular carcinoma is required for tumor growth
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Published in Hepatology (Baltimore, Md.) (01.10.2009)
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Published in Cancer research (Chicago, Ill.) (15.03.2003)
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Published in Cancer research (Chicago, Ill.) (15.03.2003)
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Abstract 509: Genomic profiling of acute lymphoblastic leukemia in ataxia telangiectasia patients reveals tight link between ATM mutations and chromothripsis
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Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Cytogenetic characterization of head and neck squamous cell carcinoma cell lines as model systems for the functional analyses of tumor-associated genes
Freier, Kolja, Hofele, Christof, Knoepfle, Karl, Gross, Madeleine, Devens, Frauke, Dyckhoff, Gerhard, Plinkert, Peter, Lichter, Peter, Herold-Mende, Christel
Published in Journal of oral pathology & medicine (01.05.2010)
Published in Journal of oral pathology & medicine (01.05.2010)
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Freier, Kolja, Flechtenmacher, Christa, Walch, Axel, Devens, Frauke, Mühling, Joachim, Lichter, Peter, Joos, Stefan, Hofele, Christof
Published in Oral oncology (01.10.2005)
Published in Oral oncology (01.10.2005)
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Recurrent NMYC copy number gain and high protein expression in basal cell carcinoma
FREIER, Kolja, FLECHTENMACHER, Christa, DEVENS, Frauke, HARTSCHUH, Wolfgang, HOFELE, Christof, LICHTER, Peter, JOOS, Stefan
Published in Oncology reports (01.05.2006)
Published in Oncology reports (01.05.2006)
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Distinct site-specific oncoprotein overexpression in head and neck squamous cell carcinoma: a tissue microarray analysis
Freier, Kolja, Bosch, Franz X, Flechtenmacher, Christa, Devens, Frauke, Benner, Axel, Lichter, Peter, Joos, Stefan, Hofele, Christof
Published in Anticancer research (01.09.2003)
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Published in Anticancer research (01.09.2003)
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Spatial and temporal transcriptomics of SHH-medulloblastoma with chromothripsis identifies multiple genetic clones that resist to treatment and lead to relapse
Kats, Ilia, Schreiber, Hannah Sophia, Simovic, Milena, Sant, Pooja, Jan-Philipp Mallm, Li, Albert, Velmurugan, Pravin, Weil, Sophie, Devens, Frauke, Sill, Martin, Jugold, Manfred, Moustafa, Mahmoud, Abdollahi, Amir, Winkler, Frank, Korshunov, Andrey, Pfister, Stefan, Stegle, Oliver, Ernst, Aurélie
Published in bioRxiv (06.03.2023)
Published in bioRxiv (06.03.2023)
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A synergistic interaction between HDAC- and PARP inhibitors in childhood tumors with chromothripsis
Umar Khalid, Simovic, Milena, Iskar, Murat, Wong, John Kl, Kumar, Rithu, Jugold, Manfred, Sill, Martin, Bolkestein, Michiel, Kolb, Thorsten, Hergt, Michaela, Devens, Frauke, Ecker, Jonas, Kool, Marcel, Milde, Till, Westermann, Frank, Lewis, Joe, Dietrich, Sascha, Pfister, Stefan, Lichter, Peter, Zapatka, Marc, Ernst, Aurelie
Published in bioRxiv (22.04.2021)
Published in bioRxiv (22.04.2021)
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