Kinetic fingerprints differentiate the mechanisms of action of anti-Aβ antibodies
Linse, Sara, Scheidt, Tom, Bernfur, Katja, Vendruscolo, Michele, Dobson, Christopher M., Cohen, Samuel I. A., Sileikis, Eimantas, Lundqvist, Martin, Qian, Fang, O’Malley, Tiernan, Bussiere, Thierry, Weinreb, Paul H., Xu, Catherine K., Meisl, Georg, Devenish, Sean R. A., Knowles, Tuomas P. J., Hansson, Oskar
Published in Nature structural & molecular biology (01.12.2020)
Published in Nature structural & molecular biology (01.12.2020)
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Journal Article
One in a Million: Flow Cytometric Sorting of Single Cell-Lysate Assays in Monodisperse Picolitre Double Emulsion Droplets for Directed Evolution
Zinchenko, Anastasia, Devenish, Sean R. A., Kintses, Balint, Colin, Pierre-Yves, Fischlechner, Martin, Hollfelder, Florian
Published in Analytical chemistry (Washington) (04.03.2014)
Published in Analytical chemistry (Washington) (04.03.2014)
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Accessing unexplored regions of sequence space in directed enzyme evolution via insertion/deletion mutagenesis
Emond, Stephane, Petek, Maya, Kay, Emily J., Heames, Brennen, Devenish, Sean R. A., Tokuriki, Nobuhiko, Hollfelder, Florian
Published in Nature communications (10.07.2020)
Published in Nature communications (10.07.2020)
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Journal Article
Microfluidic droplets: new integrated workflows for biological experiments
Kintses, Balint, van Vliet, Liisa D, Devenish, Sean RA, Hollfelder, Florian
Published in Current opinion in chemical biology (01.10.2010)
Published in Current opinion in chemical biology (01.10.2010)
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A Fully Unsupervised Compartment-on-Demand Platform for Precise Nanoliter Assays of Time-Dependent Steady-State Enzyme Kinetics and Inhibition
Gielen, Fabrice, van Vliet, Liisa, Koprowski, Bartosz T, Devenish, Sean R. A, Fischlechner, Martin, Edel, Joshua B, Niu, Xize, deMello, Andrew J, Hollfelder, Florian
Published in Analytical chemistry (Washington) (07.05.2013)
Published in Analytical chemistry (Washington) (07.05.2013)
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Journal Article
Serological fingerprints link antiviral activity of therapeutic antibodies to affinity and concentration
Fiedler, Sebastian, Devenish, Sean R. A., Morgunov, Alexey S., Ilsley, Alison, Ricci, Francesco, Emmenegger, Marc, Kosmoliaptsis, Vasilis, Theel, Elitza S., Mills, John R., Sholukh, Anton M., Aguzzi, Adriano, Iwasaki, Akiko, Lynn, Andrew K., Knowles, Tuomas P. J.
Published in Scientific reports (17.11.2022)
Published in Scientific reports (17.11.2022)
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Journal Article
Microfluidic antibody affinity profiling of alloantibody-HLA interactions in human serum
Schneider, Matthias M., Scheidt, Tom, Priddey, Ashley J., Xu, Catherine K., Hu, Mengsha, Meisl, Georg, Devenish, Sean R.A., Dobson, Christopher M., Kosmoliaptsis, Vasilis, Knowles, Tuomas P.J.
Published in Biosensors & bioelectronics (15.05.2023)
Published in Biosensors & bioelectronics (15.05.2023)
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A single mutation in the core domain of the lac repressor reduces leakiness
Gatti-Lafranconi, Pietro, Dijkman, Willem P, Devenish, Sean R A, Hollfelder, Florian
Published in Microbial cell factories (08.07.2013)
Published in Microbial cell factories (08.07.2013)
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Journal Article
FULL-MDS: Fluorescent Universal Lipid Labeling for Microfluidic Diffusional Sizing
Baron, Jasmin, Bauernhofer, Lena, Devenish, Sean R. A., Fiedler, Sebastian, Ilsley, Alison, Riedl, Sabrina, Zweytick, Dagmar, Glueck, David, Pessentheiner, Ariane, Durand, Grégory, Keller, Sandro
Published in Analytical chemistry (Washington) (17.01.2023)
Published in Analytical chemistry (Washington) (17.01.2023)
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α‑Synuclein Oligomers Displace Monomeric α‑Synuclein from Lipid Membranes
Šneiderienė, Greta, Czekalska, Magdalena A., Xu, Catherine K., Jayaram, Akhila K., Krainer, Georg, Arter, William E., Peter, Quentin A. E., Castellana-Cruz, Marta, Saar, Kadi Liis, Levin, Aviad, Mueller, Thomas, Fiedler, Sebastian, Devenish, Sean R. A., Fiegler, Heike, Kumita, Janet R., Knowles, Tuomas P. J.
Published in ACS nano (09.07.2024)
Published in ACS nano (09.07.2024)
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Journal Article
Antibody Affinity Governs the Inhibition of SARS-CoV‑2 Spike/ACE2 Binding in Patient Serum
Fiedler, Sebastian, Piziorska, Monika A., Denninger, Viola, Morgunov, Alexey S., Ilsley, Alison, Malik, Anisa Y., Schneider, Matthias M., Devenish, Sean R. A., Meisl, Georg, Kosmoliaptsis, Vasilis, Aguzzi, Adriano, Fiegler, Heike, Knowles, Tuomas P. J.
Published in ACS infectious diseases (13.08.2021)
Published in ACS infectious diseases (13.08.2021)
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Journal Article
Microfluidic Antibody Affinity Profiling Reveals the Role of Memory Reactivation and Cross-Reactivity in the Defense Against SARS-CoV‑2
Denninger, Viola, Xu, Catherine K, Meisl, Georg, Morgunov, Alexey S, Fiedler, Sebastian, Ilsley, Alison, Emmenegger, Marc, Malik, Anisa Y, Piziorska, Monika A, Schneider, Matthias M, Devenish, Sean R. A, Kosmoliaptsis, Vasilis, Aguzzi, Adriano, Fiegler, Heike, Knowles, Tuomas P. J
Published in ACS infectious diseases (08.04.2022)
Published in ACS infectious diseases (08.04.2022)
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Journal Article
Protocol to determine antibody affinity and concentration in complex solutions using microfluidic antibody affinity profiling
Emmenegger, Marc, Worth, Roland, Fiedler, Sebastian, Devenish, Sean R.A., Knowles, Tuomas P.J., Aguzzi, Adriano
Published in STAR protocols (17.03.2023)
Published in STAR protocols (17.03.2023)
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Journal Article
Both COVID-19 infection and vaccination induce high-affinity cross-clade responses to SARS-CoV-2 variants
Emmenegger, Marc, Fiedler, Sebastian, Brugger, Silvio D., Devenish, Sean R.A., Morgunov, Alexey S., Ilsley, Alison, Ricci, Francesco, Malik, Anisa Y., Scheier, Thomas, Batkitar, Leyla, Madrigal, Lidia, Rossi, Marco, Meisl, Georg, Lynn, Andrew K., Saleh, Lanja, von Eckardstein, Arnold, Knowles, Tuomas P.J., Aguzzi, Adriano
Published in iScience (19.08.2022)
Published in iScience (19.08.2022)
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LC–MS and NMR characterization of the purple chromophore formed in the o-aminobenzaldehyde assay of dihydrodipicolinate synthase
Mitsakos, Voula, Devenish, Sean R.A., O’Donnell, Paul A., Gerrard, Juliet A., Hutton, Craig A.
Published in Bioorganic & medicinal chemistry (15.02.2011)
Published in Bioorganic & medicinal chemistry (15.02.2011)
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Journal Article
Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis
Kefala, Georgia, Evans, Genevieve L, Griffin, Michael D W, Devenish, Sean R A, Pearce, F Grant, Perugini, Matthew A, Gerrard, Juliet A, Weiss, Manfred S, Dobson, Renwick C J
Published in Biochemical journal (15.04.2008)
Published in Biochemical journal (15.04.2008)
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