Brain Endothelial- and Epithelial-Specific Interferon Receptor Chain 1 Drives Virus-Induced Sickness Behavior and Cognitive Impairment
Blank, Thomas, Detje, Claudia N., Spieß, Alena, Hagemeyer, Nora, Brendecke, Stefanie M., Wolfart, Jakob, Staszewski, Ori, Zöller, Tanja, Papageorgiou, Ismini, Schneider, Justus, Paricio-Montesinos, Ricardo, Eisel, Ulrich L.M., Manahan-Vaughan, Denise, Jansen, Stephan, Lienenklaus, Stefan, Lu, Bao, Imai, Yumiko, Müller, Marcus, Goelz, Susan E., Baker, Darren P., Schwaninger, Markus, Kann, Oliver, Heikenwalder, Mathias, Kalinke, Ulrich, Prinz, Marco
Published in Immunity (Cambridge, Mass.) (19.04.2016)
Published in Immunity (Cambridge, Mass.) (19.04.2016)
Get full text
Journal Article
Type I Interferon Receptor Signaling of Neurons and Astrocytes Regulates Microglia Activation during Viral Encephalitis
Chhatbar, Chintan, Detje, Claudia N., Grabski, Elena, Borst, Katharina, Spanier, Julia, Ghita, Luca, Elliott, David A., Jordão, Marta Joana Costa, Mueller, Nora, Sutton, James, Prajeeth, Chittappen K., Gudi, Viktoria, Klein, Michael A., Prinz, Marco, Bradke, Frank, Stangel, Martin, Kalinke, Ulrich
Published in Cell reports (Cambridge) (02.10.2018)
Published in Cell reports (Cambridge) (02.10.2018)
Get full text
Journal Article
Interferon-beta expression and type I interferon receptor signaling of hepatocytes prevent hepatic necrosis and virus dissemination in Coxsackievirus B3-infected mice
Koestner, Wolfgang, Spanier, Julia, Klause, Tanja, Tegtmeyer, Pia-K, Becker, Jennifer, Herder, Vanessa, Borst, Katharina, Todt, Daniel, Lienenklaus, Stefan, Gerhauser, Ingo, Detje, Claudia N, Geffers, Robert, Langereis, Martijn A, Vondran, Florian W R, Yuan, Qinggong, van Kuppeveld, Frank J M, Ott, Michael, Staeheli, Peter, Steinmann, Eike, Baumgärtner, Wolfgang, Wacker, Frank, Kalinke, Ulrich
Published in PLoS pathogens (01.08.2018)
Published in PLoS pathogens (01.08.2018)
Get full text
Journal Article
Upon intranasal vesicular stomatitis virus infection, astrocytes in the olfactory bulb are important interferon Beta producers that protect from lethal encephalitis
Detje, Claudia N, Lienenklaus, Stefan, Chhatbar, Chintan, Spanier, Julia, Prajeeth, Chittappen K, Soldner, Claudia, Tovey, Michael G, Schlüter, Dirk, Weiss, Siegfried, Stangel, Martin, Kalinke, Ulrich
Published in Journal of virology (01.03.2015)
Published in Journal of virology (01.03.2015)
Get full text
Journal Article
IFN-β Deficiency Results in Fatal or Demyelinating Disease in C57BL/6 Mice Infected With Theiler's Murine Encephalomyelitis Viruses
Bühler, Melanie, Runft, Sandra, Li, Dandan, Götting, Jasper, Detje, Claudia N, Nippold, Vanessa, Stoff, Melanie, Beineke, Andreas, Schulz, Thomas, Kalinke, Ulrich, Baumgärtner, Wolfgang, Gerhauser, Ingo
Published in Frontiers in immunology (09.02.2022)
Published in Frontiers in immunology (09.02.2022)
Get full text
Journal Article
Independent of plasmacytoid dendritic cell (pDC) infection, pDC triggered by virus-infected cells mount enhanced type I IFN responses of different composition as opposed to pDC stimulated with free virus
Frenz, Theresa, Graalmann, Lukas, Detje, Claudia N, Döring, Marius, Grabski, Elena, Scheu, Stefanie, Kalinke, Ulrich
Published in The Journal of immunology (1950) (01.09.2014)
Published in The Journal of immunology (1950) (01.09.2014)
Get full text
Journal Article
Distinct and Nonredundant In Vivo Functions of IFNAR on Myeloid Cells Limit Autoimmunity in the Central Nervous System
Prinz, Marco, Schmidt, Hauke, Mildner, Alexander, Knobeloch, Klaus-Peter, Hanisch, Uwe-Karsten, Raasch, Jenni, Merkler, Doron, Detje, Claudia, Gutcher, Ilona, Mages, Jörg, Lang, Roland, Martin, Roland, Gold, Ralf, Becher, Burkhard, Brück, Wolfgang, Kalinke, Ulrich
Published in Immunity (Cambridge, Mass.) (01.05.2008)
Published in Immunity (Cambridge, Mass.) (01.05.2008)
Get full text
Journal Article
Local Type I IFN Receptor Signaling Protects against Virus Spread within the Central Nervous System
Detje, Claudia N, Meyer, Thomas, Schmidt, Hauke, Kreuz, Dorothea, Rose, John K, Bechmann, Ingo, Prinz, Marco, Kalinke, Ulrich
Published in The Journal of immunology (1950) (15.02.2009)
Published in The Journal of immunology (1950) (15.02.2009)
Get full text
Journal Article
Oncolytic Rodent Protoparvoviruses Evade a TLR- and RLR-Independent Antiviral Response in Transformed Cells
Angelova, Assia, Pierrard, Kristina, Detje, Claudia N, Santiago, Estelle, Grewenig, Annabel, Nüesch, Jürg P F, Kalinke, Ulrich, Ungerechts, Guy, Rommelaere, Jean, Daeffler, Laurent
Published in Pathogens (Basel) (17.04.2023)
Published in Pathogens (Basel) (17.04.2023)
Get full text
Journal Article
The type I interferon response bridles rabies virus infection and reduces pathogenicity
Chopy, Damien, Detje, Claudia N., Lafage, Mireille, Kalinke, Ulrich, Lafon, Monique
Published in Journal of neurovirology (01.08.2011)
Published in Journal of neurovirology (01.08.2011)
Get full text
Journal Article
Hepatitis C Virus Stimulates Murine CD8α-Like Dendritic Cells to Produce Type I Interferon in a TRIF-Dependent Manner
Pfaender, Stephanie, Grabski, Elena, Detje, Claudia N, Riebesehl, Nina, Lienenklaus, Stefan, Steinmann, Eike, Kalinke, Ulrich, Pietschmann, Thomas
Published in PLoS pathogens (01.07.2016)
Published in PLoS pathogens (01.07.2016)
Get full text
Journal Article
Hepatitis C Virus Stimulates Murine CD8[alpha]-Like Dendritic Cells to Produce Type I Interferon in a TRIF-Dependent Manner
Pfaender, Stephanie, Grabski, Elena, Detje, Claudia N, Riebesehl, Nina, Lienenklaus, Stefan, Steinmann, Eike, Kalinke, Ulrich, Pietschmann, Thomas
Published in PLoS pathogens (06.07.2016)
Published in PLoS pathogens (06.07.2016)
Get full text
Journal Article
Concomitant TLR/RLH signaling of radioresistant and radiosensitive cells is essential for protection against vesicular stomatitis virus infection
Spanier, Julia, Lienenklaus, Stefan, Paijo, Jennifer, Kessler, Annett, Borst, Katharina, Heindorf, Sabrina, Baker, Darren P, Kröger, Andrea, Weiss, Siegfried, Detje, Claudia N, Staeheli, Peter, Kalinke, Ulrich
Published in The Journal of immunology (1950) (15.09.2014)
Published in The Journal of immunology (1950) (15.09.2014)
Get full text
Journal Article
The antiviral drug ganciclovir does not inhibit microglial proliferation and activation
Skripuletz, Thomas, Salinas Tejedor, Laura, Prajeeth, Chittappen K, Hansmann, Florian, Chhatbar, Chintan, Kucman, Valeria, Zhang, Ning, Raddatz, Barbara B, Detje, Claudia N, Sühs, Kurt-Wolfram, Pul, Refik, Gudi, Viktoria, Kalinke, Ulrich, Baumgärtner, Wolfgang, Stangel, Martin
Published in Scientific reports (08.10.2015)
Published in Scientific reports (08.10.2015)
Get full text
Journal Article
Virus infection via the olfactory route triggers primarily astrocytes within the olfactory bulb to express IFN-beta which triggers IFNAR throughout the brain
Detje, Claudia N, Lienenklaus, Stefan, Spanier, Julia, Soldner, Claudia, Tovey, Michael G, Weiss, Siegfried, Kalinke, Ulrich
Published in Journal of neuroimmunology (01.01.2014)
Published in Journal of neuroimmunology (01.01.2014)
Get full text
Journal Article
The type I interferon response bridles rabies virus infection and reduces pathogenicity
CHOPY, Damien, DETJE, Claudia N, LAFAGE, Mireille, KALINKE, Ulrich, LAFON, Monique
Published in Journal of neurovirology (01.08.2011)
Published in Journal of neurovirology (01.08.2011)
Get full text
Journal Article
Article: Distinct and Nonredundant In Vivo Functions of IFNAR on Myeloid Cells Limit Autoimmunity in the Central Nervous System
Prinz, Marco, Schmidt, Hauke, Mildner, Alexander, Knobeloch, Klaus-Peter, Hanisch, Uwe-Karsten, Raasch, Jenni, Merkler, Doron, Detje, Claudia, Gutcher, Ilona, Mages, Jorg, Lang, Roland, Martin, Roland, Gold, Ralf, Becher, Burkhard, Bruck, Wolfgang, Kalinke, Ulrich
Published in Immunity (Cambridge, Mass.) (01.05.2008)
Published in Immunity (Cambridge, Mass.) (01.05.2008)
Get full text
Journal Article