An obesity-associated gut microbiome reprograms the intestinal epigenome and leads to altered colonic gene expression
Qin, Yufeng, Roberts, John D, Grimm, Sara A, Lih, Fred B, Deterding, Leesa J, Li, Ruifang, Chrysovergis, Kaliopi, Wade, Paul A
Published in Genome Biology (23.01.2018)
Published in Genome Biology (23.01.2018)
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Bacteria Boost Mammalian Host NAD Metabolism by Engaging the Deamidated Biosynthesis Pathway
Shats, Igor, Williams, Jason G., Liu, Juan, Makarov, Mikhail V., Wu, Xiaoyue, Lih, Fred B., Deterding, Leesa J., Lim, Chaemin, Xu, Xiaojiang, Randall, Thomas A., Lee, Ethan, Li, Wenling, Fan, Wei, Li, Jian-Liang, Sokolsky, Marina, Kabanov, Alexander V., Li, Leping, Migaud, Marie E., Locasale, Jason W., Li, Xiaoling
Published in Cell metabolism (03.03.2020)
Published in Cell metabolism (03.03.2020)
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HNF4α regulates sulfur amino acid metabolism and confers sensitivity to methionine restriction in liver cancer
Xu, Qing, Li, Yuanyuan, Gao, Xia, Kang, Kai, Williams, Jason G., Tong, Lingfeng, Liu, Juan, Ji, Ming, Deterding, Leesa J., Tong, Xuemei, Locasale, Jason W., Li, Leping, Shats, Igor, Li, Xiaoling
Published in Nature communications (07.08.2020)
Published in Nature communications (07.08.2020)
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Characterization of SARS2 Nsp15 nuclease activity reveals it's mad about U
Frazier, Meredith N, Dillard, Lucas B, Krahn, Juno M, Perera, Lalith, Williams, Jason G, Wilson, Isha M, Stewart, Zachary D, Pillon, Monica C, Deterding, Leesa J, Borgnia, Mario J, Stanley, Robin E
Published in Nucleic Acids Research (27.09.2021)
Published in Nucleic Acids Research (27.09.2021)
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Cryo-EM structures of the SARS-CoV-2 endoribonuclease Nsp15 reveal insight into nuclease specificity and dynamics
Pillon, Monica C., Frazier, Meredith N., Dillard, Lucas B., Williams, Jason G., Kocaman, Seda, Krahn, Juno M., Perera, Lalith, Hayne, Cassandra K., Gordon, Jacob, Stewart, Zachary D., Sobhany, Mack, Deterding, Leesa J., Hsu, Allen L., Dandey, Venkata P., Borgnia, Mario J., Stanley, Robin E.
Published in Nature communications (27.01.2021)
Published in Nature communications (27.01.2021)
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Cryo-EM reveals the architecture of the PELP1-WDR18 molecular scaffold
Gordon, Jacob, Chapus, Fleur L., Viverette, Elizabeth G., Williams, Jason G., Deterding, Leesa J., Krahn, Juno M., Borgnia, Mario J., Rodriguez, Joseph, Warren, Alan J., Stanley, Robin E.
Published in Nature communications (09.11.2022)
Published in Nature communications (09.11.2022)
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Immunoglobulins G from patients with ANCA-associated vasculitis are atypically glycosylated in both the Fc and Fab regions and the relation to disease activity
Lardinois, Olivier M, Deterding, Leesa J, Hess, Jacob J, Poulton, Caroline J, Henderson, Candace D, Jennette, J Charles, Nachman, Patrick H, Falk, Ronald J
Published in PloS one (28.02.2019)
Published in PloS one (28.02.2019)
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Longitudinal exposure to consumer product chemicals and changes in plasma oxylipins in pregnant women
Welch, Barrett M., Keil, Alexander P., Bommarito, Paige A., van t' Erve, Thomas Joost, Deterding, Leesa J., Williams, Jason G., Lih, Fred B., Cantonwine, David E., McElrath, Thomas F., Ferguson, Kelly K.
Published in Environment international (01.12.2021)
Published in Environment international (01.12.2021)
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Longitudinal profiles of plasma eicosanoids during pregnancy and size for gestational age at delivery: A nested case-control study
Welch, Barrett M., Keil, Alexander P., van ‘t Erve, Thomas J., Deterding, Leesa J., Williams, Jason G., Lih, Fred B., Cantonwine, David E., McElrath, Thomas F., Ferguson, Kelly K.
Published in PLoS medicine (01.08.2020)
Published in PLoS medicine (01.08.2020)
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Mass Spectrometric Identification of Oxidative Modifications of Tryptophan Residues in Proteins: Chemical Artifact or Post-Translational Modification?
Perdivara, Irina, Deterding, Leesa J., Przybylski, Michael, Tomer, Kenneth B.
Published in Journal of the American Society for Mass Spectrometry (01.07.2010)
Published in Journal of the American Society for Mass Spectrometry (01.07.2010)
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Sulfite-mediated oxidation of myeloperoxidase to a free radical: Immuno-spin trapping detection in human neutrophils
Ranguelova, Kalina, Rice, Annette B., Lardinois, Olivier M., Triquigneaux, Mathilde, Steinckwich, Natacha, Deterding, Leesa J., Garantziotis, Stavros, Mason, Ronald P.
Published in Free radical biology & medicine (01.07.2013)
Published in Free radical biology & medicine (01.07.2013)
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Elevated plasma 8-iso-prostaglandin F2α levels in human smokers originate primarily from enzymatic instead of non-enzymatic lipid peroxidation
van 't Erve, Thomas J., Lih, Fred B., Kadiiska, Maria B., Deterding, Leesa J., Mason, Ronald P.
Published in Free radical biology & medicine (01.02.2018)
Published in Free radical biology & medicine (01.02.2018)
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HMGB1 Is a Cofactor in Mammalian Base Excision Repair
Prasad, Rajendra, Liu, Yuan, Deterding, Leesa J., Poltoratsky, Vladimir P., Kedar, Padmini S., Horton, Julie K., Kanno, Shin-Ichiro, Asagoshi, Kenjiro, Hou, Esther W., Khodyreva, Svetlana N., Lavrik, Olga I., Tomer, Kenneth B., Yasui, Akira, Wilson, Samuel H.
Published in Molecular cell (07.09.2007)
Published in Molecular cell (07.09.2007)
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Site-specific radical formation in DNA induced by Cu(II)–H2O2 oxidizing system, using ESR, immuno-spin trapping, LC-MS, and MS/MS
Bhattacharjee, Suchandra, Deterding, Leesa J., Chatterjee, Saurabh, Jiang, JinJie, Ehrenshaft, Marilyn, Lardinois, Olivier, Ramirez, Dario C., Tomer, Kenneth B., Mason, Ronald P.
Published in Free radical biology & medicine (01.06.2011)
Published in Free radical biology & medicine (01.06.2011)
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Functional Pdgfra fibroblast heterogeneity in normal and fibrotic mouse lung
Trempus, Carol S, Papas, Brian N, Sifre, Maria I, Bortner, Carl D, Scappini, Erica, Tucker, Charles J, Xu, Xin, Johnson, Katina L, Deterding, Leesa J, Williams, Jason G, Johnson, Dylan J, Li, Jian-Liang, Sutton, Deloris, Ganta, Charan, Mahapatra, Debabrata, Arif, Muhammad, Basu, Abhishek, Pommerolle, Lenny, Cinar, Resat, Perl, Anne K, Garantziotis, Stavros
Published in JCI insight (22.11.2023)
Published in JCI insight (22.11.2023)
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Immuno-spin trapping of protein and DNA radicals: “Tagging” free radicals to locate and understand the redox process
Gomez-Mejiba, Sandra E., Zhai, Zili, Akram, Hammad, Deterding, Leesa J., Hensley, Kenneth, Smith, Nataliya, Towner, Rheal A., Tomer, Kenneth B., Mason, Ronald P., Ramirez, Dario C.
Published in Free radical biology & medicine (01.04.2009)
Published in Free radical biology & medicine (01.04.2009)
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Targeted oxidation of Torpedo californica acetylcholinesterase by singlet oxygen: identification of N-formylkynurenine tryptophan derivatives within the active-site gorge of its complex with the photosensitizer methylene blue
Triquigneaux, Mathilde M, Ehrenshaft, Marilyn, Roth, Esther, Silman, Israel, Ashani, Yakov, Mason, Ronald P, Weiner, Lev, Deterding, Leesa J
Published in Biochemical journal (15.11.2012)
Published in Biochemical journal (15.11.2012)
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Electron Transfer between a Tyrosyl Radical and a Cysteine Residue in Hemoproteins: Spin Trapping Analysis
Bhattacharjee, Suchandra, Deterding, Leesa J, Jiang, JinJie, Bonini, Marcelo G, Tomer, Kenneth B, Ramirez, Dario C, Mason, Ronald P
Published in Journal of the American Chemical Society (07.11.2007)
Published in Journal of the American Chemical Society (07.11.2007)
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