Development of a Green and Sustainable Manufacturing Process for Gefapixant Citrate (MK-7264) Part 3: Development of a One-Pot Formylation–Cyclization Sequence to the Diaminopyrimidine Core
Basu, Kallol, Lehnherr, Dan, Martin, Gary E, Desmond, Richard A, Lam, Yu-hong, Peng, Feng, Chung, John Y. L, Arvary, Rebecca A, Zompa, Michael A, Zhang, Si-Wei, Liu, Jinchu, Dance, Zachary E. X, Larpent, Patrick, Cohen, Ryan D, Guzman, Francisco J, Rogus, Nicholas J, Di Maso, Michael J, Ren, Hong, Maloney, Kevin M
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Published in Organic process research & development (20.11.2020)
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Asymmetric Synthesis of Telcagepant, a CGRP Receptor Antagonist for the Treatment of Migraine
Xu, Feng, Zacuto, Michael, Yoshikawa, Naoki, Desmond, Richard, Hoerrner, Scott, Itoh, Tetsuji, Journet, Michel, Humphrey, Guy R, Cowden, Cameron, Strotman, Neil, Devine, Paul
Published in Journal of organic chemistry (19.11.2010)
Published in Journal of organic chemistry (19.11.2010)
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De novo macrolide-glycolipid macrolactone hybrids: Synthesis, structure and antibiotic activity of carbohydrate-fused macrocycles
Desmond, Richard T, Magpusao, Anniefer N, Lorenc, Chris, Alverson, Jeremy B, Priestley, Nigel, Peczuh, Mark W
Published in Beilstein journal of organic chemistry (17.09.2014)
Published in Beilstein journal of organic chemistry (17.09.2014)
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Palladium-Catalyzed Regioselective Arylation of Imidazo[1,2-b][1,2,4]triazine: Synthesis of an α2/ 3-Selective GABA Agonist
Gauthier, Donald R, Limanto, John, Devine, Paul N, Desmond, Richard A, Szumigala, Ronald H, Foster, Bruce S, Volante, R. P
Published in Journal of organic chemistry (22.07.2005)
Published in Journal of organic chemistry (22.07.2005)
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Synthesis and evaluation of antimigratory and antiproliferative activities of lipid-linked [13]-macro-dilactones
Magpusao, Anniefer N., Desmond, Richard T., Billings, Katelyn J., Fenteany, Gabriel, Peczuh, Mark W.
Published in Bioorganic & medicinal chemistry letters (15.09.2010)
Published in Bioorganic & medicinal chemistry letters (15.09.2010)
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Corticolimbic mechanisms in emotional decisions
Tucker, Don M, Luu, Phan, Desmond, Jr, Richard E, Hartry-Speiser, Ann, Davey, Colin, Flaisch, Tobias
Published in Emotion (Washington, D.C.) (01.06.2003)
Published in Emotion (Washington, D.C.) (01.06.2003)
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A novel chromium trioxide catalyzed oxidation of primary alcohols to the carboxylic acids
Zhao, Mangzhu, Li, Jing, Song, Zhiguo, Desmond, Richard, Tschaen, David M., Grabowski, Edward J.J., Reider, Paul J.
Published in Tetrahedron letters (23.07.1998)
Published in Tetrahedron letters (23.07.1998)
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Scalable, efficient process for the synthesis of ( R)-3,5-bistrifluoromethylphenyl ethanol via catalytic asymmetric transfer hydrogenation and isolation as a DABCO inclusion complex
Hansen, Karl B., Chilenski, Jennifer R., Desmond, Richard, Devine, Paul N., Grabowski, Edward J.J., Heid, Richard, Kubryk, Michele, Mathre, David J., Varsolona, Richard
Published in Tetrahedron: asymmetry (14.11.2003)
Published in Tetrahedron: asymmetry (14.11.2003)
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An Efficient Chemoenzymatic Approach to (S)-γ-Fluoroleucine Ethyl Ester
Limanto, John, Shafiee, Ali, Devine, Paul N., Upadhyay, Veena, Desmond, Richard A., Foster, Bruce R., Gauthier, Donald R., Reamer, Robert A., Volante, R. P.
Published in Journal of organic chemistry (18.03.2005)
Published in Journal of organic chemistry (18.03.2005)
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Practical Asymmetric Synthesis of an Endothelin Receptor Antagonist
Song, Zhiguo J, Zhao, Mangzhu, Desmond, Richard, Devine, Paul, Tschaen, David M, Tillyer, Richard, Frey, Lisa, Heid, Richard, Xu, Feng, Foster, Bruce, Li, Jing, Reamer, Robert, Volante, Ralph, Dolling, Ulf H, Reider, Paul J, Okada, Shigemitsu, Kato, Yoshiaki, Mano, Eiichi
Published in Journal of organic chemistry (24.12.1999)
Published in Journal of organic chemistry (24.12.1999)
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A Regioselective Approach to 5-Substituted-3-amino-1,2,4-triazines
Limanto, John, Desmond, Richard A, Gauthier, Donald R, Devine, Paul N, Reamer, Robert A, Volante, R. P
Published in Organic letters (26.06.2003)
Published in Organic letters (26.06.2003)
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Journal Article
Palladium-catalyzed regioselective arylation of imidazo[1,2-b][1,2,4]triazine: synthesis of an alpha 2/3-selective GABA agonist
Gauthier, Jr, Donald R, Limanto, John, Devine, Paul N, Desmond, Richard A, Szumigala, Jr, Ronald H, Foster, Bruce S, Volante, R P
Published in Journal of organic chemistry (22.07.2005)
Published in Journal of organic chemistry (22.07.2005)
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Leveraging Synergistic Solubility in the Development of a Direct Isolation Process for Nemtabrutinib
Chen, Yonggang, Iuzzolino, Luca, Burgess, Samantha A., Chung, Cheol K., Corry, James, Crawford, Morgan, Desmond, Richard, Guetschow, Erik, Hartmanshenn, Clara, Kuhl, Nadine, Liu, Zhu, Luo, Hanlin, McQuilken, Alison C., Newman, Justin A., Ren, Hong, Thaisrivongs, David A., Wang, Zhixun, Sirota, Eric
Published in Organic process research & development (21.04.2023)
Published in Organic process research & development (21.04.2023)
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Integrating Process Development and Safety Analysis for Scale-Up of a Diborane-Generating Reduction Reaction
Armstrong, Brittany M., Behre, Taylor, Turnbull, Ben W. H., Bishara, Daniel, Hartmanshenn, Clara, McCarthy, Erin, Whittington, Michael, Ji, Yining, Jenks, Anna, Desmond, Richard, Muzzio, Daniel J., Corry, James, Zhao, Ralph, Kuhl, Nadine, Chung, Cheol K.
Published in Organic process research & development (21.04.2023)
Published in Organic process research & development (21.04.2023)
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Utilizing biocatalysis and a sulfolane-mediated reductive acetal opening to access nemtabrutinib from cyrene
Kuhl, Nadine, Turnbull, Ben W. H, Ji, Yining, Larson, Reed T, Shevlin, Michael, Prier, Christopher K, Chung, Cheol K, Desmond, Richard, Guetschow, Erik, He, Cyndi Qixin, Itoh, Tetsuji, Kuethe, Jeffrey T, Newman, Justin A, Reibarkh, Mikhail, Rivera, Nelo R, Shang, Gao, Wang, Zhixun, Zewge, Daniel, Thaisrivongs, David A
Published in Green chemistry : an international journal and green chemistry resource : GC (23.01.2023)
Published in Green chemistry : an international journal and green chemistry resource : GC (23.01.2023)
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