Frameshift indels introduced by genome editing can lead to in-frame exon skipping
Lalonde, Simon, Stone, Oliver A, Lessard, Samuel, Lavertu, Adam, Desjardins, Jessica, Beaudoin, Mélissa, Rivas, Manuel, Stainier, Didier Y R, Lettre, Guillaume
Published in PloS one (01.06.2017)
Published in PloS one (01.06.2017)
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The CIP2A-TOPBP1 axis safeguards chromosome stability and is a synthetic lethal target for BRCA-mutated cancer
Adam, Salomé, Rossi, Silvia Emma, Moatti, Nathalie, De Marco Zompit, Mara, Xue, Yibo, Ng, Timothy F, Álvarez-Quilón, Alejandro, Desjardins, Jessica, Bhaskaran, Vivek, Martino, Giovanni, Setiaputra, Dheva, Noordermeer, Sylvie M, Ohsumi, Toshiro K, Hustedt, Nicole, Szilard, Rachel K, Chaudhary, Natasha, Munro, Meagan, Veloso, Artur, Melo, Henrique, Yin, Shou Yun, Papp, Robert, Young, Jordan T F, Zinda, Michael, Stucki, Manuel, Durocher, Daniel
Published in Nature cancer (01.12.2021)
Published in Nature cancer (01.12.2021)
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CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition
Gallo, David, Young, Jordan T. F., Fourtounis, Jimmy, Martino, Giovanni, Álvarez-Quilón, Alejandro, Bernier, Cynthia, Duffy, Nicole M., Papp, Robert, Roulston, Anne, Stocco, Rino, Szychowski, Janek, Veloso, Artur, Alam, Hunain, Baruah, Prasamit S., Fortin, Alexanne Bonneau, Bowlan, Julian, Chaudhary, Natasha, Desjardins, Jessica, Dietrich, Evelyne, Fournier, Sara, Fugère-Desjardins, Chloe, Goullet de Rugy, Theo, Leclaire, Marie-Eve, Liu, Bingcan, Bhaskaran, Vivek, Mamane, Yael, Melo, Henrique, Nicolas, Olivier, Singhania, Akul, Szilard, Rachel K., Tkáč, Ján, Yin, Shou Yun, Morris, Stephen J., Zinda, Michael, Marshall, C. Gary, Durocher, Daniel
Published in Nature (London) (28.04.2022)
Published in Nature (London) (28.04.2022)
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Guiding ATR and PARP inhibitor combinationswith chemogenomic screens
Zimmermann, Michal, Bernier, Cynthia, Kaiser, Beatrice, Fournier, Sara, Li, Li, Desjardins, Jessica, Skeldon, Alexander, Rimkunas, Victoria, Veloso, Artur, Young, Jordan T F, Roulston, Anne, Zinda, Michael
Published in Cell reports (Cambridge) (12.07.2022)
Published in Cell reports (Cambridge) (12.07.2022)
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Guiding ATR and PARP inhibitor combinations with chemogenomic screens
Zimmermann, Michal, Bernier, Cynthia, Kaiser, Beatrice, Fournier, Sara, Li, Li, Desjardins, Jessica, Skeldon, Alexander, Rimkunas, Victoria, Veloso, Artur, Young, Jordan T.F., Roulston, Anne, Zinda, Michael
Published in Cell reports (Cambridge) (12.07.2022)
Published in Cell reports (Cambridge) (12.07.2022)
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Discovery of Potent, Orally Bioavailable Inhibitors of Human Cytomegalovirus
Fader, Lee, Brault, Martine, Desjardins, Jessica, Dansereau, Nathalie, Lamorte, Louie, Tremblay, Sonia, Bilodeau, François, Bordeleau, Josée, Duplessis, Martin, Gorys, Vida, Gillard, James, Gleason, James L, James, Clint, Joly, Marc-André, Kuhn, Cyrille, Llinas-Brunet, Montse, Luo, Laibin, Morency, Louis, Morin, Sébastien, Parisien, Mathieu, Poirier, Maude, Thibeault, Carl, Trinh, Thao, Sturino, Claudio, Srivastava, Sanjay, Yoakim, Christiane, Franti, Michael
Published in ACS medicinal chemistry letters (12.05.2016)
Published in ACS medicinal chemistry letters (12.05.2016)
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CIP2A is a prime synthetic-lethal target for BRCA-mutated cancers
Salomé, Adam, Rossi, Silvia Emma, Moatti, Nathalie, Mara De Marco Zompit, Ng, Timothy F, Álvarez-Quilón, Alejandro, Desjardins, Jessica, Bhaskaran, Vivek, Martino, Giovanni, Setiaputra, Dheva, Noordermeer, Sylvie M, Ohsumi, Toshiro K, Hustedt, Nicole, Szilard, Rachel K, Chaudhary, Natasha, Munro, Meagan, Veloso, Artur, Melo, Henrique, Shou Yun Yin, Papp, Robert, Jordan Tf Young, Zinda, Michael, Stucki, Manuel, Durocher, Daniel
Published in bioRxiv (08.02.2021)
Published in bioRxiv (08.02.2021)
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