In silico, in vitro and in situ models to assess interplay between CYP3A and P-gp
Mudra, Daniel R, Desino, Kelly E, Desai, Prashant V
Published in Current drug metabolism (01.10.2011)
Published in Current drug metabolism (01.10.2011)
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In Silico Absorption, Distribution, Metabolism, Excretion, and Pharmacokinetics (ADME-PK): Utility and Best Practices. An Industry Perspective from the International Consortium for Innovation through Quality in Pharmaceutical Development
Lombardo, Franco, Desai, Prashant V, Arimoto, Rieko, Desino, Kelly E, Fischer, Holger, Keefer, Christopher E, Petersson, Carl, Winiwarter, Susanne, Broccatelli, Fabio
Published in Journal of medicinal chemistry (22.11.2017)
Published in Journal of medicinal chemistry (22.11.2017)
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Journal Article
Placental ABC Transporters: Biological Impact and Pharmaceutical Significance
Joshi, Anand A., Vaidya, Soniya S., St-Pierre, Marie V., Mikheev, Andrei M., Desino, Kelly E., Nyandege, Abner N., Audus, Kenneth L., Unadkat, Jashvant D., Gerk, Phillip M.
Published in Pharmaceutical Research (01.12.2016)
Published in Pharmaceutical Research (01.12.2016)
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Journal Article
Book Review
TCP-FA4: A derivative of tranylcypromine showing improved blood–brain permeability
Desino, Kelly E., Pignatello, Rosario, Guccione, Salvatore, Basile, Livia, Ansar, Sabah, Michaelis, Mary Lou, Ramsay, Rona R., Audus, Kenneth L.
Published in Biochemical pharmacology (01.12.2009)
Published in Biochemical pharmacology (01.12.2009)
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In Silico Absorption, Distribution, Metabolism, Excretion, and Pharmacokinetics (ADME-PK): Utility and Best Practices. An Industry Perspective from the International Consortium for Innovation through Quality in Pharmaceutical Development: Miniperspective
Lombardo, Franco, Desai, Prashant V, Arimoto, Rieko, Desino, Kelly E, Fischer, Holger, Keefer, Christopher E, Petersson, Carl, Winiwarter, Susanne, Broccatelli, Fabio
Published in Journal of medicinal chemistry (22.11.2017)
Published in Journal of medicinal chemistry (22.11.2017)
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Journal Article
Hit-to-lead evaluation of a novel class of sphingosine 1-phosphate lyase inhibitors
Dinges, Jurgen, Harris, Christopher M., Wallace, Grier A., Argiriadi, Maria A., Queeney, Kara L., Perron, Denise C., Dominguez, Eric, Kebede, Tegest, Desino, Kelly E., Patel, Hetal, Vasudevan, Anil
Published in Bioorganic & medicinal chemistry letters (01.05.2016)
Published in Bioorganic & medicinal chemistry letters (01.05.2016)
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A non-toxic Hsp90 inhibitor protects neurons from Aβ-induced toxicity
Ansar, Sabah, Burlison, Joseph A., Hadden, M. Kyle, Yu, Xiao Ming, Desino, Kelly E., Bean, Jennifer, Neckers, Len, Audus, Ken L., Michaelis, Mary L., Blagg, Brian S.J.
Published in Bioorganic & medicinal chemistry letters (01.04.2007)
Published in Bioorganic & medicinal chemistry letters (01.04.2007)
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Journal Article
Paclitaxel succinate analogs: Anionic and amide introduction as a strategy to impart blood–brain barrier permeability
Turunen, Brandon J., Ge, Haibo, Oyetunji, Jariat, Desino, Kelly E., Vasandani, Veena, Güthe, Sarah, Himes, Richard H., Audus, Kenneth L., Seelig, Anna, Georg, Gunda I.
Published in Bioorganic & medicinal chemistry (15.11.2008)
Published in Bioorganic & medicinal chemistry (15.11.2008)
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Journal Article
(3R,5S,7as)-(3,5-Bis(4-fluorophenyl)tetrahydro-1H-oxazolo[3,4-c]oxazol-7a-yl)methanol, a Novel Neuroprotective Agent
Desino, Kelly E, Ansar, Sabah, Georg, Gunda I, Himes, Richard H, Michaelis, Mary Lou, Powell, Douglas R, Reiff, Emily A, Telikepalli, Hanumaiah, Audus, Kenneth L
Published in Journal of medicinal chemistry (10.12.2009)
Published in Journal of medicinal chemistry (10.12.2009)
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Journal Article
(3 R ,5 S ,7a s )-(3,5-Bis(4-fluorophenyl)tetrahydro-1 H -oxazolo[3,4- c ]oxazol-7a-yl)methanol, a Novel Neuroprotective Agent
Desino, Kelly E., Ansar, Sabah, Georg, Gunda I., Himes, Richard H., Michaelis, Mary Lou, Powell, Douglas R., Reiff, Emily A., Telikepalli, Hanumaiah, Audus, Kenneth L.
Published in Journal of medicinal chemistry (10.12.2009)
Published in Journal of medicinal chemistry (10.12.2009)
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Journal Article
A non-toxic Hsp90 inhibitor protects neurons from Abeta-induced toxicity
Ansar, Sabah, Burlison, Joseph A, Hadden, M Kyle, Yu, Xiao Ming, Desino, Kelly E, Bean, Jennifer, Neckers, Len, Audus, Ken L, Michaelis, Mary L, Blagg, Brian S J
Published in Bioorganic & medicinal chemistry letters (01.04.2007)
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Published in Bioorganic & medicinal chemistry letters (01.04.2007)
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