Placentas from women of advanced maternal age (AMA) show increased activation of the unfolded protein response (UPR) but this is not exacerbated in the presence of Fetal Growth Restriction (FGR)
Li, Xiaojia, Heazell, Alexander, Dilworth, Mark, Desforges, Michelle
Published in Placenta (Eastbourne) (07.09.2023)
Published in Placenta (Eastbourne) (07.09.2023)
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Journal Article
Placental nutrient supply and fetal growth
Desforges, Michelle, Sibley, Colin P
Published in The International journal of developmental biology (2010)
Published in The International journal of developmental biology (2010)
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Diet‐induced maternal obesity impacts feto‐placental growth and induces sex‐specific alterations in placental morphology, mitochondrial bioenergetics, dynamics, lipid metabolism and oxidative stress in mice
Napso, Tina, Lean, Samantha C., Lu, Minhui, Mort, Emily J., Desforges, Michelle, Moghimi, Ali, Bartels, Beverly, El‐Bacha, Tatiana, Fowden, Abigail L., Camm, Emily J., Sferruzzi‐Perri, Amanda N.
Published in Acta Physiologica (01.04.2022)
Published in Acta Physiologica (01.04.2022)
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Journal Article
Morphological and functional changes in placentas from prolonged pregnancies
Carroll, Amber, Desforges, Michelle, Jones, Carolyn J.P., Heazell, Alexander E.P.
Published in Placenta (Eastbourne) (01.07.2022)
Published in Placenta (Eastbourne) (01.07.2022)
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Chronic developmental hypoxia alters mitochondrial oxidative capacity and reactive oxygen species production in the fetal rat heart in a sex‐dependent manner
Smith, Kerri L. M., Swiderska, Agnieszka, Lock, Mitchell C., Graham, Lucia, Iswari, Wulan, Choudhary, Tashi, Thomas, Donna, Kowash, Hager M., Desforges, Michelle, Cottrell, Elizabeth C., Trafford, Andrew W., Giussani, Dino A., Galli, Gina L. J.
Published in Journal of pineal research (01.10.2022)
Published in Journal of pineal research (01.10.2022)
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Human placental uptake of glutamine and glutamate is reduced in fetal growth restriction
McIntyre, Kirsty R, Vincent, Kirsty M M, Hayward, Christina E, Li, Xiaojia, Sibley, Colin P, Desforges, Michelle, Greenwood, Susan L, Dilworth, Mark R
Published in Scientific reports (01.10.2020)
Published in Scientific reports (01.10.2020)
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P-025. Comparison of methods for determining PlGF and sFlt-1 levels in maternal circulation in pregnancies complicated by placental dysfunction
Vincent, Kirsty M.M., Dooley, Megan, Desforges, Michelle, Myers, Jenny E., Cottrell, Elizabeth, Higgins, Lucy E.
Published in Pregnancy hypertension (01.09.2021)
Published in Pregnancy hypertension (01.09.2021)
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Taurine in normal pregnancy and preeclampsia: Fetal-placental-maternal cross talk
Desforges, Michelle, Hirst, Chloe, Price, Marcus, Greenwood, Susan
Published in Placenta (Eastbourne) (01.09.2014)
Published in Placenta (Eastbourne) (01.09.2014)
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Journal Article
Effects of taurine depletion on human placental syncytiotrophoblast renewal and susceptibility to oxidative stress
Desforges, Michelle, Whittaker, Hannah, Farmer, Etaoin, Sibley, Colin P, Greenwood, Susan L
Published in Advances in experimental medicine and biology (2015)
Published in Advances in experimental medicine and biology (2015)
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Reduced placental taurine transporter (TauT) activity in pregnancies complicated by pre-eclampsia and maternal obesity
Desforges, Michelle, Ditchfield, Andrea, Hirst, Chloe R, Pegorie, Claire, Martyn-Smith, Kathryn, Sibley, Colin P, Greenwood, Susan L
Published in Advances in experimental medicine and biology (2013)
Published in Advances in experimental medicine and biology (2013)
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The SNAT4 isoform of the system A amino acid transporter is functional in human placental microvillous plasma membrane
Desforges, M., Mynett, K. J., Jones, R. L., Greenwood, S. L., Westwood, M., Sibley, C. P., Glazier, J. D.
Published in The Journal of physiology (01.01.2009)
Published in The Journal of physiology (01.01.2009)
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In Vitro Human Placental Studies to Support Adenovirus-Mediated VEGF-D ΔNΔC Maternal Gene Therapy for the Treatment of Severe Early-Onset Fetal Growth Restriction
Desforges, Michelle, Rogue, Alexandra, Pearson, Nick, Rossi, Carlo, Olearo, Elena, Forster, Roy, Lees, Mark, Sebire, Neil J, Greenwood, Susan L, Sibley, Colin P, David, Anna L, Brownbill, Paul
Published in Human gene therapy. Clinical development (01.03.2018)
Published in Human gene therapy. Clinical development (01.03.2018)
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