From Riluzole to Dexpramipexole via Substituted-Benzothiazole Derivatives for Amyotrophic Lateral Sclerosis Disease Treatment: Case Studies
Mignani, Serge, Majoral, Jean-Pierre, Desaphy, Jean-François, Lentini, Giovanni
Published in Molecules (Basel, Switzerland) (22.07.2020)
Published in Molecules (Basel, Switzerland) (22.07.2020)
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Journal Article
Coexistence of SCN4A and CLCN1 mutations in a family with atypical myotonic features: A clinical and functional study
Vacchiano, Veria, Brugnoni, Raffaella, Campanale, Carmen, Imbrici, Paola, Dinoi, Giorgia, Canioni, Eleonora, Laghetti, Paola, Saltarella, Ilaria, Altamura, Concetta, Maggi, Lorenzo, Liguori, Rocco, Donadio, Vincenzo, Desaphy, Jean-François
Published in Experimental neurology (01.04.2023)
Published in Experimental neurology (01.04.2023)
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Journal Article
Ion Channel Involvement in Tumor Drug Resistance
Altamura, Concetta, Gavazzo, Paola, Pusch, Michael, Desaphy, Jean-François
Published in Journal of personalized medicine (03.02.2022)
Published in Journal of personalized medicine (03.02.2022)
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Journal Article
Pharmacogenetics of myotonic hNav1.4 sodium channel variants situated near the fast inactivation gate
Farinato, Alessandro, Altamura, Concetta, Imbrici, Paola, Maggi, Lorenzo, Bernasconi, Pia, Mantegazza, Renato, Pasquali, Livia, Siciliano, Gabriele, Lo Monaco, Mauro, Vial, Christophe, Sternberg, Damien, Carratù, Maria Rosaria, Conte, Diana, Desaphy, Jean-François
Published in Pharmacological research (01.03.2019)
Published in Pharmacological research (01.03.2019)
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Journal Article
Targeted Therapies for Skeletal Muscle Ion Channelopathies: Systematic Review and Steps Towards Precision Medicine
Desaphy, Jean-François, Altamura, Concetta, Vicart, Savine, Fontaine, Bertrand
Published in Journal of Neuromuscular Diseases (01.01.2021)
Published in Journal of Neuromuscular Diseases (01.01.2021)
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Book Review
Journal Article
Target mutation-driven drug discovery
Altamura, Concetta, Conte, Diana, Carratù, Maria Rosaria, Desaphy, Jean-François
Published in Current medicinal chemistry (01.09.2022)
Published in Current medicinal chemistry (01.09.2022)
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Journal Article
Immersive and Non-Immersive Virtual Reality for Pain and Anxiety Management in Pediatric Patients with Hematological or Solid Cancer: A Systematic Review
Comparcini, Dania, Simonetti, Valentina, Galli, Francesco, Saltarella, Ilaria, Altamura, Concetta, Tomietto, Marco, Desaphy, Jean-François, Cicolini, Giancarlo
Published in Cancers (03.02.2023)
Published in Cancers (03.02.2023)
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Journal Article
Editorial: New Insights in Skeletal Muscle Channelopathies - A Rapidly Expanding Field
Maggi, Lorenzo, Matthews, Emma, Desaphy, Jean-François
Published in Frontiers in neurology (17.12.2020)
Published in Frontiers in neurology (17.12.2020)
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Journal Article
Increased sarcolemma chloride conductance as one of the mechanisms of action of carbonic anhydrase inhibitors in muscle excitability disorders
Altamura, Concetta, Fonzino, Adriano, Tarantino, Nancy, Conte, Elena, Liantonio, Antonella, Imbrici, Paola, Carratù, Maria Rosaria, Pierno, Sabata, Desaphy, Jean-François
Published in Experimental neurology (01.08.2021)
Published in Experimental neurology (01.08.2021)
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Journal Article
Anti-Angiogenic Activity of Drugs in Multiple Myeloma
Saltarella, Ilaria, Altamura, Concetta, Campanale, Carmen, Laghetti, Paola, Vacca, Angelo, Frassanito, Maria Antonia, Desaphy, Jean-François
Published in Cancers (27.03.2023)
Published in Cancers (27.03.2023)
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Journal Article
Privileged scaffold-based design to identify a novel drug-like 5-HT7 receptor-preferring agonist to target Fragile X syndrome
Lacivita, Enza, Niso, Mauro, Stama, Madia Letizia, Arzuaga, Anna, Altamura, Concetta, Costa, Lara, Desaphy, Jean-François, Ragozzino, Michael E., Ciranna, Lucia, Leopoldo, Marcello
Published in European journal of medicinal chemistry (01.08.2020)
Published in European journal of medicinal chemistry (01.08.2020)
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Journal Article
Safinamide's potential in treating nondystrophic myotonias: Inhibition of skeletal muscle voltage-gated sodium channels and skeletal muscle hyperexcitability in vitro and in vivo
Desaphy, Jean-François, Farinato, Alessandro, Altamura, Concetta, De Bellis, Michela, Imbrici, Paola, Tarantino, Nancy, Caccia, Carla, Melloni, Elsa, Padoani, Gloria, Vailati, Silvia, Keywood, Charlotte, Carratù, Maria Rosaria, De Luca, Annamaria, Conte, Diana, Pierno, Sabata
Published in Experimental neurology (01.06.2020)
Published in Experimental neurology (01.06.2020)
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Journal Article
Expert opinion on mexiletine treatment in adult patients with myotonic dystrophy
Wahbi, Karim, Bassez, Guillaume, Duchateau, Josselin, Salort-Campana, Emmanuelle, Vicart, Savine, Desaphy, Jean-François, Labombarda, Fabien, Sellal, Jean-Marc, Deharo, Jean-Claude
Published in Archives of cardiovascular diseases (01.06.2024)
Published in Archives of cardiovascular diseases (01.06.2024)
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Journal Article
Toward precision medicine in myotonic syndromes
De Bellis, Michela, Camerino, Diana Conte, Desaphy, Jean-François
Published in Oncotarget (28.02.2017)
Published in Oncotarget (28.02.2017)
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Journal Article
Corrigendum: Bioisosteric Modification of To042: Synthesis and Evaluation of Promising Use‐Dependent Inhibitors of Voltage‐Gated Sodium Channels
Milani, Gualtiero, Cavalluzzi, Maria Maddalena, Altamura, Concetta, Santoro, Antonella, Perrone, Mariagrazia, Muraglia, Marilena, Colabufo, Nicola Antonio, Corbo, Filomena, Casalino, Elisabetta, Franchini, Carlo, Pisano, Isabella, Desaphy, Jean‐François, Carrieri, Antonio, Carocci, Alessia, Lentini, Giovanni
Published in ChemMedChem (05.04.2022)
Published in ChemMedChem (05.04.2022)
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Journal Article
Translational approach to address therapy in myotonia permanens due to a new SCN4A mutation
Desaphy, Jean-François, Carbonara, Roberta, D'Amico, Adele, Modoni, Anna, Roussel, Julien, Imbrici, Paola, Pagliarani, Serena, Lucchiari, Sabrina, Lo Monaco, Mauro, Conte Camerino, Diana
Published in Neurology (31.05.2016)
Published in Neurology (31.05.2016)
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Journal Article