Protein Phosphatase 2A (PP2A) mutations in brain function, development, and neurologic disease
Verbinnen, Iris, Vaneynde, Pieter, Reynhout, Sara, Lenaerts, Lisa, Derua, Rita, Houge, Gunnar, Janssens, Veerle
Published in Biochemical Society transactions (27.08.2021)
Published in Biochemical Society transactions (27.08.2021)
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Sustained SREBP-1-dependent lipogenesis as a key mediator of resistance to BRAF-targeted therapy
Talebi, Ali, Dehairs, Jonas, Rambow, Florian, Rogiers, Aljosja, Nittner, David, Derua, Rita, Vanderhoydonc, Frank, Duarte, Joao A. G., Bosisio, Francesca, Van den Eynde, Kathleen, Nys, Kris, Pérez, Mónica Vara, Agostinis, Patrizia, Waelkens, Etienne, Van den Oord, Joost, Fendt, Sarah-Maria, Marine, Jean-Christophe, Swinnen, Johannes V.
Published in Nature communications (27.06.2018)
Published in Nature communications (27.06.2018)
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De novo Lipogenesis Protects Cancer Cells from Free Radicals and Chemotherapeutics by Promoting Membrane Lipid Saturation
RYSMAN, Evelien, BRUSSELMANS, Koen, VANDERHOYDONC, Frank, SMANS, Karine, WAELKENS, Etienne, VERHOEVEN, Guido, SWINNEN, Johannes V, SCHEYS, Katryn, TIMMERMANS, Leen, DERUA, Rita, MUNCK, Sebastian, VAN VELDHOVEN, Paul P, WALTREGNY, David, DANIËLS, Veerle W, MACHIELS, Jelle
Published in Cancer research (Chicago, Ill.) (15.10.2010)
Published in Cancer research (Chicago, Ill.) (15.10.2010)
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Split‐BioID: a proximity biotinylation assay for dimerization‐dependent protein interactions
De Munter, Sofie, Görnemann, Janina, Derua, Rita, Lesage, Bart, Qian, Junbin, Heroes, Ewald, Waelkens, Etienne, Van Eynde, Aleyde, Beullens, Monique, Bollen, Mathieu
Published in FEBS letters (01.01.2017)
Published in FEBS letters (01.01.2017)
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A substrate-trapping strategy for protein phosphatase PP1 holoenzymes using hypoactive subunit fusions
Wu, Dan, De Wever, Veerle, Derua, Rita, Winkler, Claudia, Beullens, Monique, Van Eynde, Aleyde, Bollen, Mathieu
Published in The Journal of biological chemistry (28.09.2018)
Published in The Journal of biological chemistry (28.09.2018)
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Preoperative administration of the 5-HT4 receptor agonist prucalopride reduces intestinal inflammation and shortens postoperative ileus via cholinergic enteric neurons
Stakenborg, Nathalie, Labeeuw, Evelien, Gomez-Pinilla, Pedro J, De Schepper, Sebastiaan, Aerts, Raymond, Goverse, Gera, Farro, Giovanna, Appeltans, Iris, Meroni, Elisa, Stakenborg, Michelle, Viola, Maria Francesca, Gonzalez-Dominguez, Erika, Bosmans, Goele, Alpizar, Yeranddy A, Wolthuis, Albert, D’Hoore, Andre, Van Beek, Kim, Verheijden, Simon, Verhaegen, Marleen, Derua, Rita, Waelkens, Etienne, Moretti, Milena, Gotti, Cecilia, Augustijns, Patrick, Talavera, Karel, Vanden Berghe, Pieter, Matteoli, Gianluca, Boeckxstaens, Guy E
Published in Gut (01.08.2019)
Published in Gut (01.08.2019)
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Recurrent PPP2R1A Mutations in Uterine Cancer Act through a Dominant-Negative Mechanism to Promote Malignant Cell Growth
Haesen, Dorien, Abbasi Asbagh, Layka, Derua, Rita, Hubert, Antoine, Schrauwen, Stefanie, Hoorne, Yana, Amant, Frédéric, Waelkens, Etienne, Sablina, Anna, Janssens, Veerle
Published in Cancer research (Chicago, Ill.) (01.10.2016)
Published in Cancer research (Chicago, Ill.) (01.10.2016)
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Non‐small cell lung cancer is characterized by dramatic changes in phospholipid profiles
Marien, Eyra, Meister, Michael, Muley, Thomas, Fieuws, Steffen, Bordel, Sergio, Derua, Rita, Spraggins, Jeffrey, Van de Plas, Raf, Dehairs, Jonas, Wouters, Jens, Bagadi, Muralidhararao, Dienemann, Hendrik, Thomas, Michael, Schnabel, Philipp A., Caprioli, Richard M., Waelkens, Etienne, Swinnen, Johannes V.
Published in International journal of cancer (01.10.2015)
Published in International journal of cancer (01.10.2015)
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ELOVL5 Is a Critical and Targetable Fatty Acid Elongase in Prostate Cancer
Centenera, Margaret M, Scott, Julia S, Machiels, Jelle, Nassar, Zeyad D, Miller, Deanna C, Zinonos, Irene, Dehairs, Jonas, Burvenich, Ingrid J G, Zadra, Giorgia, Chetta, Paolo M, Bango, Clyde, Evergren, Emma, Ryan, Natalie K, Gillis, Joanna L, Mah, Chui Yan, Tieu, Terence, Hanson, Adrienne R, Carelli, Ryan, Bloch, Katarzyna, Panagopoulos, Vasilios, Waelkens, Etienne, Derua, Rita, Williams, Elizabeth D, Evdokiou, Andreas, Cifuentes-Rius, Anna, Voelcker, Nicolas H, Mills, Ian G, Tilley, Wayne D, Scott, Andrew M, Loda, Massimo, Selth, Luke A, Swinnen, Johannes V, Butler, Lisa M
Published in Cancer research (Chicago, Ill.) (01.04.2021)
Published in Cancer research (Chicago, Ill.) (01.04.2021)
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Stress-induced inflammation evoked by immunogenic cell death is blunted by the IRE1α kinase inhibitor KIRA6 through HSP60 targeting
Rufo, Nicole, Korovesis, Dimitris, Van Eygen, Sofie, Derua, Rita, Garg, Abhishek D., Finotello, Francesca, Vara-Perez, Monica, Rožanc, Jan, Dewaele, Michael, de Witte, Peter A., Alexopoulos, Leonidas G., Janssens, Sophie, Sinkkonen, Lasse, Sauter, Thomas, Verhelst, Steven H. L., Agostinis, Patrizia
Published in Cell death and differentiation (01.01.2022)
Published in Cell death and differentiation (01.01.2022)
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Structural mechanism for inhibition of PP2A-B56α and oncogenicity by CIP2A
Pavic, Karolina, Gupta, Nikhil, Omella, Judit Domènech, Derua, Rita, Aakula, Anna, Huhtaniemi, Riikka, Määttä, Juha A., Höfflin, Nico, Okkeri, Juha, Wang, Zhizhi, Kauko, Otto, Varjus, Roosa, Honkanen, Henrik, Abankwa, Daniel, Köhn, Maja, Hytönen, Vesa P., Xu, Wenqing, Nilsson, Jakob, Page, Rebecca, Janssens, Veerle, Leitner, Alexander, Westermarck, Jukka
Published in Nature communications (28.02.2023)
Published in Nature communications (28.02.2023)
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Dephosphorylation of the HIV-1 restriction factor SAMHD1 is mediated by PP2A-B55α holoenzymes during mitotic exit
Schott, Kerstin, Fuchs, Nina V., Derua, Rita, Mahboubi, Bijan, Schnellbächer, Esther, Seifried, Janna, Tondera, Christiane, Schmitz, Heike, Shepard, Caitlin, Brandariz-Nuñez, Alberto, Diaz-Griffero, Felipe, Reuter, Andreas, Kim, Baek, Janssens, Veerle, König, Renate
Published in Nature communications (08.06.2018)
Published in Nature communications (08.06.2018)
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Human pancreatic cancer patients with Epithelial-to-Mesenchymal Transition and an aggressive phenotype show a disturbed balance in Protein Phosphatase Type 2A expression and functionality
van Pelt, Jos, Meeusen, Bob, Derua, Rita, Guffens, Liesbeth, Van Cutsem, Eric, Janssens, Veerle, Verslype, Chris
Published in Journal of translational medicine (11.05.2023)
Published in Journal of translational medicine (11.05.2023)
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Ceramide analog [18F]F-HPA-12 detects sphingolipid disbalance in the brain of Alzheimer’s disease transgenic mice by functioning as a metabolic probe
Crivelli, Simone M., van Kruining, Daan, Luo, Qian, Stevens, Jo A. A., Giovagnoni, Caterina, Paulus, Andreas, Bauwens, Matthias, Berkes, Dusan, de Vries, Helga E., Mulder, Monique T., Walter, Jochen, Waelkens, Etienne, Derua, Rita, Swinnen, Johannes V., Dehairs, Jonas, Mottaghy, Felix M., Losen, Mario, Bieberich, Erhard, Martinez-Martinez, Pilar
Published in Scientific reports (09.11.2020)
Published in Scientific reports (09.11.2020)
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SHIP2 controls plasma membrane PI(4,5)P2 thereby participating in the control of cell migration in 1321 N1 glioblastoma cells
Elong Edimo, William's, Ghosh, Somadri, Derua, Rita, Janssens, Veerle, Waelkens, Etienne, Vanderwinden, Jean-Marie, Robe, Pierre, Erneux, Christophe
Published in Journal of cell science (15.03.2016)
Published in Journal of cell science (15.03.2016)
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The multifunctional protein E4F1 links P53 to lipid metabolism in adipocytes
Lacroix, Matthieu, Linares, Laetitia K., Rueda-Rincon, Natalia, Bloch, Katarzyna, Di Michele, Michela, De Blasio, Carlo, Fau, Caroline, Gayte, Laurie, Blanchet, Emilie, Mairal, Aline, Derua, Rita, Cardona, Fernando, Beuzelin, Diane, Annicotte, Jean-Sebastien, Pirot, Nelly, Torro, Adeline, Tinahones, Francisco J., Bernex, Florence, Bertrand-Michel, Justine, Langin, Dominique, Fajas, Lluis, Swinnen, Johannes V., Le Cam, Laurent
Published in Nature communications (02.12.2021)
Published in Nature communications (02.12.2021)
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Pharmacological activation of the C5a receptor leads to stimulation of the β-adrenergic receptor and alleviates cognitive impairment in a murine model of familial Alzheimer’s disease
Fella, Eleni, Papacharalambous, Revekka, Kynigopoulos, Demos, Ioannou, Maria, Derua, Rita, Christodoulou, Christiana, Stylianou, Myrto, Karaiskos, Christos, Kagiava, Alexia, Petroula, Gerasimou, Pierides, Chryso, Kyriakou, Maria, Koumas, Laura, Costeas, Paul, Panayiotou, Elena
Published in Frontiers in immunology (26.08.2022)
Published in Frontiers in immunology (26.08.2022)
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Complementarity determining regions in SARS-CoV-2 hybrid immunity
Frans, Glynis, Dillaerts, Doreen, Dehaemers, Tom, Van Elslande, Jan, De Leeuw, Jonas, Boon, Lise, Maes, Wim, Callewaert, Nico, Calcoen, Bas, Ancheva, Lina, Cockx, Maaike, Geukens, Nick, Arat, Kusay, Derua, Rita, Vermeersch, Pieter, Carpentier, Sebastien Christian, Bossuyt, Xavier
Published in Frontiers in immunology (21.02.2023)
Published in Frontiers in immunology (21.02.2023)
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Differential protein–protein interactions of LRRK1 and LRRK2 indicate roles in distinct cellular signaling pathways
Reyniers, Lauran, Del Giudice, Maria Grazia, Civiero, Laura, Belluzzi, Elisa, Lobbestael, Evy, Beilina, Alexandra, Arrigoni, Giorgio, Derua, Rita, Waelkens, Etienne, Li, Yan, Crosio, Claudia, Iaccarino, Ciro, Cookson, Mark R., Baekelandt, Veerle, Greggio, Elisa, Taymans, Jean‐Marc
Published in Journal of neurochemistry (01.10.2014)
Published in Journal of neurochemistry (01.10.2014)
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