Drugging RAS: Know the enemy
Papke, Bjoern, Der, Channing J.
Published in Science (American Association for the Advancement of Science) (17.03.2017)
Published in Science (American Association for the Advancement of Science) (17.03.2017)
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Journal Article
KRAS: The Critical Driver and Therapeutic Target for Pancreatic Cancer
Waters, Andrew M, Der, Channing J
Published in Cold Spring Harbor perspectives in medicine (01.09.2018)
Published in Cold Spring Harbor perspectives in medicine (01.09.2018)
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Journal Article
Targeting RAS Membrane Association: Back to the Future for Anti-RAS Drug Discovery?
Cox, Adrienne D, Der, Channing J, Philips, Mark R
Published in Clinical cancer research (15.04.2015)
Published in Clinical cancer research (15.04.2015)
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Journal Article
Drugging the undruggable RAS: Mission Possible?
Cox, Adrienne D., Fesik, Stephen W., Kimmelman, Alec C., Luo, Ji, Der, Channing J.
Published in Nature reviews. Drug discovery (01.11.2014)
Published in Nature reviews. Drug discovery (01.11.2014)
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Journal Article
KRAS: feeding pancreatic cancer proliferation
Bryant, Kirsten L., Mancias, Joseph D., Kimmelman, Alec C., Der, Channing J.
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.02.2014)
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.02.2014)
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Journal Article
Ras superfamily GEFs and GAPs: validated and tractable targets for cancer therapy?
Der, Channing J, Vigil, Dominico, Cherfils, Jacqueline, Rossman, Kent L
Published in Nature reviews. Cancer (01.12.2010)
Published in Nature reviews. Cancer (01.12.2010)
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Journal Article
The role of wild type RAS isoforms in cancer
Zhou, Bingying, Der, Channing J., Cox, Adrienne D.
Published in Seminars in cell & developmental biology (01.10.2016)
Published in Seminars in cell & developmental biology (01.10.2016)
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Journal Article
Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer
Bryant, Kirsten L., Stalnecker, Clint A., Zeitouni, Daniel, Klomp, Jennifer E., Peng, Sen, Tikunov, Andrey P., Gunda, Venugopal, Pierobon, Mariaelena, Waters, Andrew M., George, Samuel D., Tomar, Garima, Papke, Björn, Hobbs, G. Aaron, Yan, Liang, Hayes, Tikvah K., Diehl, J. Nathaniel, Goode, Gennifer D., Chaika, Nina V., Wang, Yingxue, Zhang, Guo-Fang, Witkiewicz, Agnieszka K., Knudsen, Erik S., Petricoin, Emanuel F., Singh, Pankaj K., Macdonald, Jeffrey M., Tran, Nhan L., Lyssiotis, Costas A., Ying, Haoqiang, Kimmelman, Alec C., Cox, Adrienne D., Der, Channing J.
Published in Nature medicine (01.04.2019)
Published in Nature medicine (01.04.2019)
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Journal Article
KRAS Mutant Pancreatic Cancer: No Lone Path to an Effective Treatment
Zeitouni, Daniel, Pylayeva-Gupta, Yuliya, Der, Channing J, Bryant, Kirsten L
Published in Cancers (18.04.2016)
Published in Cancers (18.04.2016)
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Journal Article
Book Review
KRAS takes the road to destruction
Cox, Adrienne D, Der, Channing J
Published in Science (American Association for the Advancement of Science) (20.09.2024)
Published in Science (American Association for the Advancement of Science) (20.09.2024)
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Journal Article
Blocking autophagy to starve pancreatic cancer
Bryant, Kirsten L., Der, Channing J.
Published in Nature reviews. Molecular cell biology (01.05.2019)
Published in Nature reviews. Molecular cell biology (01.05.2019)
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Journal Article
KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism
Vaseva, Angelina V., Blake, Devon R., Gilbert, Thomas S.K., Ng, Serina, Hostetter, Galen, Azam, Salma H., Ozkan-Dagliyan, Irem, Gautam, Prson, Bryant, Kirsten L., Pearce, Kenneth H., Herring, Laura E., Han, Haiyong, Graves, Lee M., Witkiewicz, Agnieszka K., Knudsen, Erik S., Pecot, Chad V., Rashid, Naim, Houghton, Peter J., Wennerberg, Krister, Cox, Adrienne D., Der, Channing J.
Published in Cancer cell (12.11.2018)
Published in Cancer cell (12.11.2018)
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Journal Article
Computational design of chemogenetic and optogenetic split proteins
Dagliyan, Onur, Krokhotin, Andrey, Ozkan-Dagliyan, Irem, Deiters, Alexander, Der, Channing J., Hahn, Klaus M., Dokholyan, Nikolay V.
Published in Nature communications (02.10.2018)
Published in Nature communications (02.10.2018)
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Journal Article
Mist1+ gastric isthmus stem cells are regulated by Wnt5a and expand in response to injury and inflammation in mice
Nienhüser, Henrik, Kim, Woosook, Malagola, Ermanno, Ruan, Tuo, Valenti, Giovanni, Middelhoff, Moritz, Bass, Adam, Der, Channing J, Hayakawa, Yoku, Wang, Timothy C
Published in Gut (01.04.2021)
Published in Gut (01.04.2021)
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Journal Article
Personalized Medicine in Non–Small-Cell Lung Cancer: Is KRAS a Useful Marker in Selecting Patients for Epidermal Growth Factor Receptor–Targeted Therapy?
ROBERTS, Patrick J, STINCHCOMBE, Thomas E, DER, Channing J, SOCINSKI, Mark A
Published in Journal of clinical oncology (01.11.2010)
Published in Journal of clinical oncology (01.11.2010)
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Journal Article