Freeze-Drying Above the Glass Transition Temperature in Amorphous Protein Formulations While Maintaining Product Quality and Improving Process Efficiency
Depaz, Roberto A., Pansare, Swapnil, Patel, Sajal Manubhai
Published in Journal of pharmaceutical sciences (01.01.2016)
Published in Journal of pharmaceutical sciences (01.01.2016)
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Journal Article
Water Proton NMR: A Tool for Protein Aggregation Characterization
Taraban, Marc B, DePaz, Roberto A, Lobo, Brian, Yu, Y. Bruce
Published in Analytical chemistry (Washington) (16.05.2017)
Published in Analytical chemistry (Washington) (16.05.2017)
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Journal Article
Quantitation of Trace Levels of DNA Released from Disrupted Adeno-Associated Virus Gene Therapy Vectors
Bee, Jared S., O'Berry, Kristin, Zhang, Yu (Zoe), Phillippi, Megan Kuhn, Kaushal, Akanksha, DePaz, Roberto A., Marshall, Tristan
Published in Journal of pharmaceutical sciences (01.09.2021)
Published in Journal of pharmaceutical sciences (01.09.2021)
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Journal Article
Development of a stable lyophilized adeno-associated virus gene therapy formulation
Zhang, Yu (Zoe), DePaz, Roberto A., Bee, Jared S., Marshall, Tristan
Published in International journal of pharmaceutics (05.09.2021)
Published in International journal of pharmaceutics (05.09.2021)
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Journal Article
Use of Water Proton NMR to Characterize Protein Aggregates: Gauging the Response and Sensitivity
Taraban, Marc B, DePaz, Roberto A, Lobo, Brian, Yu, Y. Bruce
Published in Analytical chemistry (Washington) (19.03.2019)
Published in Analytical chemistry (Washington) (19.03.2019)
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Journal Article
Mechanistic Studies and Formulation Mitigations of Adeno-associated Virus Capsid Rupture During Freezing and Thawing: Mechanisms of Freeze/Thaw Induced AAV Rupture
Bee, Jared S, Zhang, Yu, Finkner, Sheyla, O'Berry, Kristin, Kaushal, Akanksha, Phillippi, Megan Kuhn, DePaz, Roberto A, Webber, Keith, Marshall, Tristan
Published in Journal of pharmaceutical sciences (01.07.2022)
Published in Journal of pharmaceutical sciences (01.07.2022)
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Journal Article
Cross-Linked Silicone Coating: A Novel Prefilled Syringe Technology That Reduces Subvisible Particles and Maintains Compatibility with Biologics
Depaz, Roberto A., Chevolleau, Tzvetelina, Jouffray, Sébastien, Narwal, Roja, Dimitrova, Mariana N.
Published in Journal of pharmaceutical sciences (01.05.2014)
Published in Journal of pharmaceutical sciences (01.05.2014)
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Journal Article
Effects of drying methods and additives on the structure, function, and storage stability of subtilisin: role of protein conformation and molecular mobility
DePaz, Roberto A, Dale, Douglas A, Barnett, Christopher C, Carpenter, John F, Gaertner, Alfred L, Randolph, Theodore W
Published in Enzyme and microbial technology (01.11.2002)
Published in Enzyme and microbial technology (01.11.2002)
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Journal Article
Noninvasive detection of nanoparticle clustering by water proton NMR
Taraban, Marc B, Truong, Huy C, Ilavsky, Jan, DePaz, Roberto A, Lobo, Brian, Yu, Y Bruce
Published in Translational materials research (01.06.2017)
Published in Translational materials research (01.06.2017)
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Journal Article
Mechanistic Studies and Formulation Mitigations of Adeno-associated Virus Capsid Rupture During Freezing and Thawing
Bee, Jared S., Zhang, Yu, Finkner, Sheyla, O'Berry, Kristin, Kaushal, Akanksha, Phillippi, Megan Kuhn, DePaz, Roberto A., Webber, Keith, Marshall, Tristan
Published in Journal of pharmaceutical sciences (01.07.2022)
Published in Journal of pharmaceutical sciences (01.07.2022)
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Journal Article
Freeze-Drying Above the Glass Transition Temperature in Amorphous Protein Formulations While Maintaining Product Quality and Improving Process Efficiency: Pharmaceutical Biotechnology
Depaz, Roberto A, Pansare, Swapnil, Patel, Sajal Manubhai
Published in Journal of pharmaceutical sciences (01.01.2016)
Published in Journal of pharmaceutical sciences (01.01.2016)
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Journal Article
The Excluding Effects of Sucrose on a Protein Chemical Degradation Pathway: Methionine Oxidation in Subtilisin
DePaz, Roberto A., Barnett, Christopher C., Dale, Douglas A., Carpenter, John F., Gaertner, Alfred L., Randolph, Theodore W.
Published in Archives of biochemistry and biophysics (01.12.2000)
Published in Archives of biochemistry and biophysics (01.12.2000)
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Journal Article