Glycogen and its metabolism: some new developments and old themes
Roach, Peter J, Depaoli-Roach, Anna A, Hurley, Thomas D, Tagliabracci, Vincent S
Published in Biochemical journal (01.02.2012)
Published in Biochemical journal (01.02.2012)
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Phosphate Incorporation during Glycogen Synthesis and Lafora Disease
Tagliabracci, Vincent S., Heiss, Christian, Karthik, Chandra, Contreras, Christopher J., Glushka, John, Ishihara, Mayumi, Azadi, Parastoo, Hurley, Thomas D., DePaoli-Roach, Anna A., Roach, Peter J.
Published in Cell metabolism (02.03.2011)
Published in Cell metabolism (02.03.2011)
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GYS1 or PPP1R3C deficiency rescues murine adult polyglucosan body disease
Chown, Erin E., Wang, Peixiang, Zhao, Xiaochu, Crowder, Justin J., Strober, Jordan W., Sullivan, Mitchell A., Xue, Yunlin, Bennett, Cody S., Perri, Ami M., Evers, Bret M., Roach, Peter J., Depaoli‐Roach, Anna A., Akman, H. Orhan, Pederson, Bartholomew A., Minassian, Berge A.
Published in Annals of clinical and translational neurology (01.11.2020)
Published in Annals of clinical and translational neurology (01.11.2020)
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Discovery and Development of Small-Molecule Inhibitors of Glycogen Synthase
Tang, Buyun, Frasinyuk, Mykhaylo S, Chikwana, Vimbai M, Mahalingan, Krishna K, Morgan, Cynthia A, Segvich, Dyann M, Bondarenko, Svitlana P, Mrug, Galyna P, Wyrebek, Przemyslaw, Watt, David S, DePaoli-Roach, Anna A, Roach, Peter J, Hurley, Thomas D
Published in Journal of medicinal chemistry (09.04.2020)
Published in Journal of medicinal chemistry (09.04.2020)
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The structural mechanism of human glycogen synthesis by the GYS1-GYG1 complex
Fastman, Nathan M., Liu, Yuxi, Ramanan, Vyas, Merritt, Hanne, Ambing, Eileen, DePaoli-Roach, Anna A., Roach, Peter J., Hurley, Thomas D., Mellem, Kevin T., Ullman, Julie C., Green, Eric, Morgans, David, Tzitzilonis, Christos
Published in Cell reports (Cambridge) (05.07.2022)
Published in Cell reports (Cambridge) (05.07.2022)
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Genetic Depletion of the Malin E3 Ubiquitin Ligase in Mice Leads to Lafora Bodies and the Accumulation of Insoluble Laforin
DePaoli-Roach, Anna A., Tagliabracci, Vincent S., Segvich, Dyann M., Meyer, Catalina M., Irimia, Jose M., Roach, Peter J.
Published in The Journal of biological chemistry (13.08.2010)
Published in The Journal of biological chemistry (13.08.2010)
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Abnormal Metabolism of Glycogen Phosphate as a Cause for Lafora Disease
Tagliabracci, Vincent S., Girard, Jean Marie, Segvich, Dyann, Meyer, Catalina, Turnbull, Julie, Zhao, Xiaochu, Minassian, Berge A., DePaoli-Roach, Anna A., Roach, Peter J.
Published in The Journal of biological chemistry (05.12.2008)
Published in The Journal of biological chemistry (05.12.2008)
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Starch Binding Domain-containing Protein 1/Genethonin 1 Is a Novel Participant in Glycogen Metabolism
Jiang, Sixin, Heller, Brigitte, Tagliabracci, Vincent S., Zhai, Lanmin, Irimia, Jose M., DePaoli-Roach, Anna A., Wells, Clark D., Skurat, Alexander V., Roach, Peter J.
Published in The Journal of biological chemistry (05.11.2010)
Published in The Journal of biological chemistry (05.11.2010)
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PTG depletion removes Lafora bodies and rescues the fatal epilepsy of Lafora disease
Turnbull, Julie, DePaoli-Roach, Anna A, Zhao, Xiaochu, Cortez, Miguel A, Pencea, Nela, Tiberia, Erica, Piliguian, Mark, Roach, Peter J, Wang, Peixiang, Ackerley, Cameron A, Minassian, Berge A
Published in PLoS genetics (01.04.2011)
Published in PLoS genetics (01.04.2011)
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Structural Basis for Regulation of Protein Phosphatase 1 by Inhibitor-2
Hurley, Thomas D., Yang, Jie, Zhang, Lili, Goodwin, Kristie D., Zou, Qin, Cortese, Marc, Dunker, A. Keith, DePaoli-Roach, Anna A.
Published in The Journal of biological chemistry (28.09.2007)
Published in The Journal of biological chemistry (28.09.2007)
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Laforin is a glycogen phosphatase, deficiency of which leads to elevated phosphorylation of glycogen in vivo
Tagliabracci, Vincent S, Turnbull, Julie, Wang, Wei, Girard, Jean-Marie, Zhao, Xiaochu, Skurat, Alexander V, Delgado-Escueta, Antonio V, Minassian, Berge A, DePaoli-Roach, Anna A, Roach, Peter J
Published in Proceedings of the National Academy of Sciences - PNAS (04.12.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (04.12.2007)
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Glycogen Phosphomonoester Distribution in Mouse Models of the Progressive Myoclonic Epilepsy, Lafora Disease
DePaoli-Roach, Anna A., Contreras, Christopher J., Segvich, Dyann M., Heiss, Christian, Ishihara, Mayumi, Azadi, Parastoo, Roach, Peter J.
Published in The Journal of biological chemistry (09.01.2015)
Published in The Journal of biological chemistry (09.01.2015)
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Journal Article
Enhancement of Cardiac Function and Suppression of Heart Failure Progression By Inhibition of Protein Phosphatase 1
Pathak, Anand, del Monte, Federica, Zhao, Wen, Schultz, Jo-El, Lorenz, John N, Bodi, Ilona, Weiser, Doug, Hahn, Harvey, Carr, Andrew N, Syed, Faisal, Mavila, Nirmala, Jha, Leena, Qian, Jiang, Marreez, Yehia, Chen, Guoli, McGraw, Dennis W, Heist, E Kevin, Guerrero, J Luis, DePaoli-Roach, Anna A, Hajjar, Roger J, Kranias, Evangelia G
Published in Circulation research (15.04.2005)
Published in Circulation research (15.04.2005)
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Multiple Glycogen-binding Sites in Eukaryotic Glycogen Synthase Are Required for High Catalytic Efficiency toward Glycogen
Baskaran, Sulochanadevi, Chikwana, Vimbai M., Contreras, Christopher J., Davis, Keri D., Wilson, Wayne A., DePaoli-Roach, Anna A., Roach, Peter J., Hurley, Thomas D.
Published in The Journal of biological chemistry (30.09.2011)
Published in The Journal of biological chemistry (30.09.2011)
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Journal Article
Glucose Metabolism in Mice Lacking Muscle Glycogen Synthase
PEDERSON, Bartholomew A, SCHROEDER, Jill M, PARKER, Gretchen E, SMITH, Micah W, DEPAOLI-ROACH, Anna A, ROACH, Peter J
Published in Diabetes (New York, N.Y.) (01.12.2005)
Published in Diabetes (New York, N.Y.) (01.12.2005)
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Type 1 Phosphatase, a Negative Regulator of Cardiac Function
Carr, Andrew N., Schmidt, Albrecht G., Suzuki, Yoichi, del Monte, Federica, Sato, Yoji, Lanner, Carita, Breeden, Kristine, Jing, Shao-Ling, Allen, Patrick B., Greengard, Paul, Yatani, Atsuko, Hoit, Brian D., Grupp, Ingrid L., Hajjar, Roger J., DePaoli-Roach, Anna A., Kranias, Evangelia G.
Published in Molecular and Cellular Biology (01.06.2002)
Published in Molecular and Cellular Biology (01.06.2002)
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Journal Article
Abnormal Cardiac Development in the Absence of Heart Glycogen
Pederson, Bartholomew A., Chen, Hanying, Schroeder, Jill M., Shou, Weinian, DePaoli-Roach, Anna A., Roach, Peter J.
Published in Molecular and Cellular Biology (01.08.2004)
Published in Molecular and Cellular Biology (01.08.2004)
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Journal Article
Phosphorylation of TPX2 by Plx1 enhances activation of Aurora A
Eckerdt, Frank, Pascreau, Gaetan, Phistry, Meridee, Lewellyn, Andrea L., DePaoli-Roach, Anna A., Maller, James L.
Published in Cell cycle (Georgetown, Tex.) (01.08.2009)
Published in Cell cycle (Georgetown, Tex.) (01.08.2009)
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