A 30-year journey from volume-regulated anion currents to molecular structure of the LRRC8 channel
Strange, Kevin, Yamada, Toshiki, Denton, Jerod S
Published in The Journal of general physiology (04.02.2019)
Published in The Journal of general physiology (04.02.2019)
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Journal Article
Cryo-EM structures of an LRRC8 chimera with native functional properties reveal heptameric assembly
Takahashi, Hirohide, Yamada, Toshiki, Denton, Jerod S, Strange, Kevin, Karakas, Erkan
Published in eLife (10.03.2023)
Published in eLife (10.03.2023)
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Journal Article
Low potassium activation of proximal mTOR/AKT signaling is mediated by Kir4.2
Zhang, Yahua, Bock, Fabian, Ferdaus, Mohammed, Arroyo, Juan Pablo, L Rose, Kristie, Patel, Purvi, Denton, Jerod S., Delpire, Eric, Weinstein, Alan M., Zhang, Ming-Zhi, Harris, Raymond C., Terker, Andrew S.
Published in Nature communications (17.06.2024)
Published in Nature communications (17.06.2024)
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Discovery, Characterization, and Effects on Renal Fluid and Electrolyte Excretion of the Kir4.1 Potassium Channel Pore Blocker, VU0134992
Kharade, Sujay V, Kurata, Haruto, Bender, Aaron M, Blobaum, Anna L, Figueroa, Eric E, Duran, Amanda, Kramer, Meghan, Days, Emily, Vinson, Paige, Flores, Daniel, Satlin, Lisa M, Meiler, Jens, Weaver, C David, Lindsley, Craig W, Hopkins, Corey R, Denton, Jerod S
Published in Molecular pharmacology (01.08.2018)
Published in Molecular pharmacology (01.08.2018)
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Journal Article
Pharmacological Correction of Trafficking Defects in ATP-sensitive Potassium Channels Caused by Sulfonylurea Receptor 1 Mutations
Martin, Gregory M, Rex, Emily A, Devaraneni, Prasanna, Denton, Jerod S, Boodhansingh, Kara E, DeLeon, Diva D, Stanley, Charles A, Shyng, Show-Ling
Published in The Journal of biological chemistry (14.10.2016)
Published in The Journal of biological chemistry (14.10.2016)
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Journal Article
High-Throughput Screening of Myometrial Calcium-Mobilization to Identify Modulators of Uterine Contractility
Herington, Jennifer L, Swale, Daniel R, Brown, Naoko, Shelton, Elaine L, Choi, Hyehun, Williams, Charles H, Hong, Charles C, Paria, Bibhash C, Denton, Jerod S, Reese, Jeff
Published in PloS one (24.11.2015)
Published in PloS one (24.11.2015)
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Journal Article
Associations between KCNJ6 (GIRK2) gene polymorphisms and pain-related phenotypes
Bruehl, Stephen, Denton, Jerod S., Lonergan, Daniel, Koran, Mary Ellen, Chont, Melissa, Sobey, Christopher, Fernando, Shanik, Bush, William S., Mishra, Puneet, Thornton-Wells, Tricia A.
Published in Pain (Amsterdam) (01.12.2013)
Published in Pain (Amsterdam) (01.12.2013)
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Journal Article
Discovery and characterization of a potent and selective inhibitor of Aedes aegypti inward rectifier potassium channels
Raphemot, Rene, Rouhier, Matthew F, Swale, Daniel R, Days, Emily, Weaver, C David, Lovell, Kimberly M, Konkel, Leah C, Engers, Darren W, Bollinger, Sean R, Bollinger, Sean F, Hopkins, Corey, Piermarini, Peter M, Denton, Jerod S
Published in PloS one (06.11.2014)
Published in PloS one (06.11.2014)
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Journal Article
Eliciting renal failure in mosquitoes with a small-molecule inhibitor of inward-rectifying potassium channels
Raphemot, Rene, Rouhier, Matthew F, Hopkins, Corey R, Gogliotti, Rocco D, Lovell, Kimberly M, Hine, Rebecca M, Ghosalkar, Dhairyasheel, Longo, Anthony, Beyenbach, Klaus W, Denton, Jerod S, Piermarini, Peter M
Published in PloS one (29.05.2013)
Published in PloS one (29.05.2013)
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Journal Article
Discovery and Characterization of VU0529331, a Synthetic Small-Molecule Activator of Homomeric G Protein-Gated, Inwardly Rectifying, Potassium (GIRK) Channels
Kozek, Krystian A, Du, Yu, Sharma, Swagat, Prael, Francis J, Spitznagel, Brittany D, Kharade, Sujay V, Denton, Jerod S, Hopkins, Corey R, Weaver, C. David
Published in ACS chemical neuroscience (16.01.2019)
Published in ACS chemical neuroscience (16.01.2019)
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Journal Article
Computational and Functional Analyses of a Small-Molecule Binding Site in ROMK
Swale, Daniel R., Sheehan, Jonathan H., Banerjee, Sreedatta, Husni, Afeef S., Nguyen, Thuy T., Meiler, Jens, Denton, Jerod S.
Published in Biophysical journal (10.03.2015)
Published in Biophysical journal (10.03.2015)
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Journal Article
High-Throughput Screening Reveals a Small-Molecule Inhibitor of the Renal Outer Medullary Potassium Channel and Kir7.1
Lewis, L Michelle, Bhave, Gautam, Chauder, Brian A, Banerjee, Sreedatta, Lornsen, Katharina A, Redha, Rey, Fallen, Katherine, Lindsley, Craig W, Weaver, C David, Denton, Jerod S
Published in Molecular pharmacology (01.11.2009)
Published in Molecular pharmacology (01.11.2009)
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Journal Article
The LRRC8 volume‐regulated anion channel inhibitor, DCPIB, inhibits mitochondrial respiration independently of the channel
Afzal, Aqeela, Figueroa, Eric E., Kharade, Sujay V., Bittman, Kevin, Matlock, Brittany K., Flaherty, David K., Denton, Jerod S.
Published in Physiological reports (01.12.2019)
Published in Physiological reports (01.12.2019)
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Journal Article
The inwardly rectifying K+ channel KIR7.1 controls uterine excitability throughout pregnancy
McCloskey, Conor, Rada, Cara, Bailey, Elizabeth, McCavera, Samantha, van den Berg, Hugo A, Atia, Jolene, Rand, David A, Shmygol, Anatoly, Chan, Yi‐Wah, Quenby, Siobhan, Brosens, Jan J, Vatish, Manu, Zhang, Jie, Denton, Jerod S, Taggart, Michael J, Kettleborough, Catherine, Tickle, David, Jerman, Jeff, Wright, Paul, Dale, Timothy, Kanumilli, Srinivasan, Trezise, Derek J, Thornton, Steve, Brown, Pamela, Catalano, Roberto, Lin, Nan, England, Sarah K, Blanks, Andrew M
Published in EMBO molecular medicine (01.09.2014)
Published in EMBO molecular medicine (01.09.2014)
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Journal Article
Special collection on inward rectifying K + channels
Denton, Jerod S, Delpire, Eric
Published in American Journal of Physiology: Cell Physiology (01.03.2023)
Published in American Journal of Physiology: Cell Physiology (01.03.2023)
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