PARP-1 Activation Requires Local Unfolding of an Autoinhibitory Domain
Dawicki-McKenna, Jennine M., Langelier, Marie-France, DeNizio, Jamie E., Riccio, Amanda A., Cao, Connie D., Karch, Kelly R., McCauley, Michael, Steffen, Jamin D., Black, Ben E., Pascal, John M.
Published in Molecular cell (03.12.2015)
Published in Molecular cell (03.12.2015)
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In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates
Musunuru, Kiran, Chadwick, Alexandra C., Mizoguchi, Taiji, Garcia, Sara P., DeNizio, Jamie E., Reiss, Caroline W., Wang, Kui, Iyer, Sowmya, Dutta, Chaitali, Clendaniel, Victoria, Amaonye, Michael, Beach, Aaron, Berth, Kathleen, Biswas, Souvik, Braun, Maurine C., Chen, Huei-Mei, Colace, Thomas V., Ganey, John D., Gangopadhyay, Soumyashree A., Garrity, Ryan, Kasiewicz, Lisa N., Lavoie, Jennifer, Madsen, James A., Matsumoto, Yuri, Mazzola, Anne Marie, Nasrullah, Yusuf S., Nneji, Joseph, Ren, Huilan, Sanjeev, Athul, Shay, Madeleine, Stahley, Mary R., Fan, Steven H. Y., Tam, Ying K., Gaudelli, Nicole M., Ciaramella, Giuseppe, Stolz, Leslie E., Malyala, Padma, Cheng, Christopher J., Rajeev, Kallanthottathil G., Rohde, Ellen, Bellinger, Andrew M., Kathiresan, Sekar
Published in Nature (London) (20.05.2021)
Published in Nature (London) (20.05.2021)
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Nondestructive, base-resolution sequencing of 5-hydroxymethylcytosine using a DNA deaminase
Schutsky, Emily K, DeNizio, Jamie E, Hu, Peng, Liu, Monica Yun, Nabel, Christopher S, Fabyanic, Emily B, Hwang, Young, Bushman, Frederic D, Wu, Hao, Kohli, Rahul M
Published in Nature biotechnology (01.12.2018)
Published in Nature biotechnology (01.12.2018)
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Journal Article
Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells
Fraietta, Joseph A., Nobles, Christopher L., Sammons, Morgan A., Lundh, Stefan, Carty, Shannon A., Reich, Tyler J., Cogdill, Alexandria P., Morrissette, Jennifer J. D., DeNizio, Jamie E., Reddy, Shantan, Hwang, Young, Gohil, Mercy, Kulikovskaya, Irina, Nazimuddin, Farzana, Gupta, Minnal, Chen, Fang, Everett, John K., Alexander, Katherine A., Lin-Shiao, Enrique, Gee, Marvin H., Liu, Xiaojun, Young, Regina M., Ambrose, David, Wang, Yan, Xu, Jun, Jordan, Martha S., Marcucci, Katherine T., Levine, Bruce L., Garcia, K. Christopher, Zhao, Yangbing, Kalos, Michael, Porter, David L., Kohli, Rahul M., Lacey, Simon F., Berger, Shelley L., Bushman, Frederic D., June, Carl H., Melenhorst, J. Joseph
Published in Nature (London) (01.06.2018)
Published in Nature (London) (01.06.2018)
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Journal Article
Functionally distinct roles for TET-oxidized 5-methylcytosine bases in somatic reprogramming to pluripotency
Caldwell, Blake A., Liu, Monica Yun, Prasasya, Rexxi D., Wang, Tong, DeNizio, Jamie E., Leu, N. Adrian, Amoh, Nana Yaa A., Krapp, Christopher, Lan, Yemin, Shields, Emily J., Bonasio, Roberto, Lengner, Christopher J., Kohli, Rahul M., Bartolomei, Marisa S.
Published in Molecular cell (18.02.2021)
Published in Molecular cell (18.02.2021)
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Journal Article
TET-TDG Active DNA Demethylation at CpG and Non-CpG Sites
DeNizio, Jamie E., Dow, Blaine J., Serrano, Juan C., Ghanty, Uday, Drohat, Alexander C., Kohli, Rahul M.
Published in Journal of molecular biology (16.04.2021)
Published in Journal of molecular biology (16.04.2021)
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APOBEC3A efficiently deaminates methylated, but not TET-oxidized, cytosine bases in DNA
Schutsky, Emily K, Nabel, Christopher S, Davis, Amy K F, DeNizio, Jamie E, Kohli, Rahul M
Published in Nucleic acids research (27.07.2017)
Published in Nucleic acids research (27.07.2017)
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Both tails and the centromere targeting domain of CENP-A are required for centromere establishment
Logsdon, Glennis A, Barrey, Evelyne J, Bassett, Emily A, DeNizio, Jamie E, Guo, Lucie Y, Panchenko, Tanya, Dawicki-McKenna, Jennine M, Heun, Patrick, Black, Ben E
Published in The Journal of cell biology (02.03.2015)
Published in The Journal of cell biology (02.03.2015)
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Selectivity and Promiscuity in TET-Mediated Oxidation of 5‑Methylcytosine in DNA and RNA
DeNizio, Jamie E, Liu, Monica Yun, Leddin, Emmett M, Cisneros, G. Andrés, Kohli, Rahul M
Published in Biochemistry (Easton) (05.02.2019)
Published in Biochemistry (Easton) (05.02.2019)
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BET bromodomain protein inhibition reverses chimeric antigen receptor extinction and reinvigorates exhausted T cells in chronic lymphocytic leukemia
Kong, Weimin, Dimitri, Alexander, Wang, Wenliang, Jung, In-Young, Ott, Christopher J, Fasolino, Maria, Wang, Yan, Kulikovskaya, Irina, Gupta, Minnal, Yoder, Todd, DeNizio, Jamie E, Everett, John K, Williams, Erik F, Xu, Jun, Scholler, John, Reich, Tyler J, Bhoj, Vijay G, Haines, Kathleen M, Maus, Marcela V, Melenhorst, J. Joseph, Young, Regina M, Jadlowsky, Julie K, Marcucci, Katherine T, Bradner, James E, Levine, Bruce L, Porter, David L, Bushman, Frederic D, Kohli, Rahul M, June, Carl H, Davis, Megan M, Lacey, Simon F, Vahedi, Golnaz, Fraietta, Joseph A
Published in The Journal of clinical investigation (15.08.2021)
Published in The Journal of clinical investigation (15.08.2021)
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Direct enzymatic sequencing of 5-methylcytosine at single-base resolution
Wang, Tong, Fowler, Johanna M., Liu, Laura, Loo, Christian E., Luo, Meiqi, Schutsky, Emily K., Berríos, Kiara N., DeNizio, Jamie E., Dvorak, Ashley, Downey, Nick, Montermoso, Saira, Pingul, Bianca Y., Nasrallah, MacLean, Gosal, Walraj S., Wu, Hao, Kohli, Rahul M.
Published in Nature chemical biology (01.08.2023)
Published in Nature chemical biology (01.08.2023)
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Tuning Hsp104 specificity to selectively detoxify α-synuclein
Mack, Korrie L., Kim, Hanna, Barbieri, Edward M., Lin, JiaBei, Braganza, Sylvanne, Jackrel, Meredith E., DeNizio, Jamie E., Yan, Xiaohui, Chuang, Edward, Tariq, Amber, Cupo, Ryan R., Castellano, Laura M., Caldwell, Kim A., Caldwell, Guy A., Shorter, James
Published in Molecular cell (21.09.2023)
Published in Molecular cell (21.09.2023)
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Journal Article
Mutations along a TET2 active site scaffold stall oxidation at 5-hydroxymethylcytosine
Liu, Monica Yun, Torabifard, Hedieh, Crawford, Daniel J, DeNizio, Jamie E, Cao, Xing-Jun, Garcia, Benjamin A, Cisneros, G Andrés, Kohli, Rahul M
Published in Nature chemical biology (01.02.2017)
Published in Nature chemical biology (01.02.2017)
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Journal Article
The expanding scope and impact of epigenetic cytosine modifications
Liu, Monica Yun, DeNizio, Jamie E, Schutsky, Emily K, Kohli, Rahul M
Published in Current opinion in chemical biology (01.08.2016)
Published in Current opinion in chemical biology (01.08.2016)
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Identification and interrogation of combinatorial histone modifications
Karch, Kelly R, Denizio, Jamie E, Black, Ben E, Garcia, Benjamin A
Published in Frontiers in genetics (20.12.2013)
Published in Frontiers in genetics (20.12.2013)
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HJURP Uses Distinct CENP-A Surfaces to Recognize and to Stabilize CENP-A/Histone H4 for Centromere Assembly
Bassett, Emily A., DeNizio, Jamie, Barnhart-Dailey, Meghan C., Panchenko, Tanya, Sekulic, Nikolina, Rogers, Danielle J., Foltz, Daniel R., Black, Ben E.
Published in Developmental cell (17.04.2012)
Published in Developmental cell (17.04.2012)
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