Steering Siglec–Sialic Acid Interactions on Living Cells using Bioorthogonal Chemistry
Büll, Christian, Heise, Torben, van Hilten, Niek, Pijnenborg, Johan F. A., Bloemendal, Victor R. L. J., Gerrits, Lotte, Kers‐Rebel, Esther D., Ritschel, Tina, den Brok, Martijn H., Adema, Gosse J., Boltje, Thomas J.
Published in Angewandte Chemie International Edition (13.03.2017)
Published in Angewandte Chemie International Edition (13.03.2017)
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Journal Article
Sialic Acids Sweeten a Tumor's Life
BÜLL, Christian, STOEL, Marieke A, DEN BROK, Martijn H, ADEMA, Gosse J
Published in Cancer research (Chicago, Ill.) (15.06.2014)
Published in Cancer research (Chicago, Ill.) (15.06.2014)
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Journal Article
In situ tumor ablation creates an antigen source for the generation of antitumor immunity
BROK, Martijn H. M. G. M. Den, SUTMULLER, Roger P. M, VAN DER VOORT, Robbert, BENNINK, Erik J, FIGDOR, Carl G, RUERS, Theo J. M, ADEMA, Gosse J
Published in Cancer research (Chicago, Ill.) (01.06.2004)
Published in Cancer research (Chicago, Ill.) (01.06.2004)
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Journal Article
Route of administration of the TLR9 agonist CpG critically determines the efficacy of cancer immunotherapy in mice
Nierkens, Stefan, den Brok, Martijn H, Roelofsen, Thijs, Wagenaars, Jori A L, Figdor, Carl G, Ruers, Theo J, Adema, Gosse J
Published in PloS one (18.12.2009)
Published in PloS one (18.12.2009)
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Journal Article
Sialic Acid Blockade Suppresses Tumor Growth by Enhancing T-cell-Mediated Tumor Immunity
Büll, Christian, Boltje, Thomas J, Balneger, Natasja, Weischer, Sarah M, Wassink, Melissa, van Gemst, Jasper J, Bloemendal, Victor R, Boon, Louis, van der Vlag, Johan, Heise, Torben, den Brok, Martijn H, Adema, Gosse J
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Thermal and mechanical high-intensity focused ultrasound: perspectives on tumor ablation, immune effects and combination strategies
van den Bijgaart, Renske J. E., Eikelenboom, Dylan C., Hoogenboom, Martijn, Fütterer, Jurgen J., den Brok, Martijn H., Adema, Gosse J.
Published in Cancer Immunology, Immunotherapy (01.02.2017)
Published in Cancer Immunology, Immunotherapy (01.02.2017)
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Journal Article
Book Review
Mechanical High-Intensity Focused Ultrasound Destruction of Soft Tissue: Working Mechanisms and Physiologic Effects
Hoogenboom, Martijn, Eikelenboom, Dylan, den Brok, Martijn H, Heerschap, Arend, Fütterer, Jurgen J, Adema, Gosse J
Published in Ultrasound in medicine & biology (01.06.2015)
Published in Ultrasound in medicine & biology (01.06.2015)
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Journal Article
Saponin-based adjuvants induce cross-presentation in dendritic cells by intracellular lipid body formation
den Brok, Martijn H., Büll, Christian, Wassink, Melissa, de Graaf, Annemarie M., Wagenaars, Jori A., Minderman, Marthe, Thakur, Mayank, Amigorena, Sebastian, Rijke, Eric O., Schrier, Carla C., Adema, Gosse J.
Published in Nature communications (07.11.2016)
Published in Nature communications (07.11.2016)
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Journal Article
Targeting aberrant sialylation in cancer cells using a fluorinated sialic acid analog impairs adhesion, migration, and in vivo tumor growth
Büll, Christian, Boltje, Thomas J, Wassink, Melissa, de Graaf, Annemarie M A, van Delft, Floris L, den Brok, Martijn H, Adema, Gosse J
Published in Molecular cancer therapeutics (01.10.2013)
Published in Molecular cancer therapeutics (01.10.2013)
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Journal Article
Targeted Delivery of a Sialic Acid-Blocking Glycomimetic to Cancer Cells Inhibits Metastatic Spread
Büll, Christian, Boltje, Thomas Jan, van Dinther, Eric A. W, Peters, Timo, de Graaf, Annemarie M. A, Leusen, Jeanette H. W, Kreutz, Martin, Figdor, Carl G, den Brok, Martijn H, Adema, Gosse J
Published in ACS nano (27.01.2015)
Published in ACS nano (27.01.2015)
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Journal Article
Combined sialic acid and histone deacetylase (HDAC) inhibitor treatment up-regulates the neuroblastoma antigen GD2
van den Bijgaart, Renske J.E., Kroesen, Michiel, Wassink, Melissa, Brok, Ingrid C., Kers-Rebel, Esther D., Boon, Louis, Heise, Torben, van Scherpenzeel, Monique, Lefeber, Dirk J., Boltje, Thomas J., den Brok, Martijn H., Hoogerbrugge, Peter M., Büll, Christian, Adema, Gosse J.
Published in The Journal of biological chemistry (22.03.2019)
Published in The Journal of biological chemistry (22.03.2019)
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Journal Article
Immune Adjuvant Efficacy of CpG Oligonucleotide in Cancer Treatment Is Founded Specifically upon TLR9 Function in Plasmacytoid Dendritic Cells
NIERKENS, Stefan, DEN BROK, Martijn H, ADEMA, Gosse J, JANSSEN, Edith M, GARCIA, Zacharias, TOGHER, Susan, WAGENAARS, Jori, WASSINK, Melissa, BOON, Louis, RUERS, Theo J, FIGDOR, Carl G, SCHOENBERGER, Stephen P
Published in Cancer research (Chicago, Ill.) (15.10.2011)
Published in Cancer research (Chicago, Ill.) (15.10.2011)
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Journal Article
A transplantable TH‐MYCN transgenic tumor model in C57Bl/6 mice for preclinical immunological studies in neuroblastoma
Kroesen, Michiel, Nierkens, Stefan, Ansems, Marleen, Wassink, Melissa, Orentas, Rimas J., Boon, Louis, Brok, Martijn H., Hoogerbrugge, Peter M., Adema, Gosse J.
Published in International journal of cancer (15.03.2014)
Published in International journal of cancer (15.03.2014)
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Journal Article
Recognition of Coxiella burnetii by Toll-like Receptors and Nucleotide-Binding Oligomerization Domain-like Receptors
Ammerdorffer, Anne, Schoffelen, Teske, Gresnigt, Mark S., Oosting, Marije, den Brok, Martijn H., Abdollahi-Roodsaz, Shahla, Kanneganti, Thirumala-Devi, de Jong, Dirk J., van Deuren, Marcel, Roest, Hendrik-Jan, Rebel, Johanna M., Netea, Mihai G., Joosten, Leo A. B., Sprang, Tom
Published in The Journal of infectious diseases (15.03.2015)
Published in The Journal of infectious diseases (15.03.2015)
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Journal Article
Synergy between in situ cryoablation and TLR9 stimulation results in a highly effective in vivo dendritic cell vaccine
DEN BROK, Martijn H. M. G. M, SUTMULLER, Roger P. M, NIERKENS, Stefan, BENNINK, Erik J, TOONEN, Liza W. J, FIGDOR, Carl G, RUERS, Theo J. M, ADEMA, Gosse J
Published in Cancer research (Chicago, Ill.) (15.07.2006)
Published in Cancer research (Chicago, Ill.) (15.07.2006)
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Journal Article
Tumor ablation plus co-administration of CpG and saponin adjuvants affects IL-1 production and multifunctional T cell numbers in tumor draining lymph nodes
Raaijmakers, Tonke K, van den Bijgaart, Renske J E, den Brok, Martijn H, Wassink, Melissa, de Graaf, Annemarie, Wagenaars, Jori A, Nierkens, Stefan, Ansems, Marleen, Scheffer, Gert Jan, Adema, Gosse J
Published in Journal for immunotherapy of cancer (01.05.2020)
Published in Journal for immunotherapy of cancer (01.05.2020)
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Journal Article
Sweet escape: Sialic acids in tumor immune evasion
Büll, Christian, den Brok, Martijn H., Adema, Gosse J.
Published in Biochimica et biophysica acta (01.08.2014)
Published in Biochimica et biophysica acta (01.08.2014)
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Journal Article
Saponin-based adjuvant-induced dendritic cell cross-presentation is dependent on PERK activation
Huis in ’t Veld, Lisa G. M., Ho, Nataschja I., Wassink, Melisssa, den Brok, Martijn H., Adema, Gosse J.
Published in Cellular and molecular life sciences : CMLS (01.05.2022)
Published in Cellular and molecular life sciences : CMLS (01.05.2022)
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Journal Article
Lipid Droplets as Immune Modulators in Myeloid Cells
den Brok, Martijn H., Raaijmakers, Tonke K., Collado-Camps, Estel, Adema, Gosse J.
Published in Trends in immunology (01.05.2018)
Published in Trends in immunology (01.05.2018)
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Journal Article
DC-STAMP knock-down deregulates cytokine production and T-cell stimulatory capacity of LPS-matured dendritic cells
Sanecka, Anna, Ansems, Marleen, Prosser, Amy C, Danielski, Katharina, Warner, Kathrin, den Brok, Martijn H, Jansen, Bastiaan J H, Eleveld-Trancikova, Dagmar, Adema, Gosse J
Published in BMC immunology (06.10.2011)
Published in BMC immunology (06.10.2011)
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Journal Article