An Update on the Structure of hERG
Butler, Andrew, Helliwell, Matthew V, Zhang, Yihong, Hancox, Jules C, Dempsey, Christopher E
Published in Frontiers in pharmacology (24.01.2020)
Published in Frontiers in pharmacology (24.01.2020)
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Journal Article
Ranolazine inhibition of hERG potassium channels: Drug–pore interactions and reduced potency against inactivation mutants
Du, Chunyun, Zhang, Yihong, El Harchi, Aziza, Dempsey, Christopher E, Hancox, Jules C
Published in Journal of molecular and cellular cardiology (01.09.2014)
Published in Journal of molecular and cellular cardiology (01.09.2014)
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Journal Article
Evolutionary coupling analysis guides identification of mistrafficking-sensitive variants in cardiac K+ channels: Validation with hERG
Zhang, Yihong, Grimwood, Amy L., Hancox, Jules C., Harmer, Stephen C., Dempsey, Christopher E.
Published in Frontiers in pharmacology (20.10.2022)
Published in Frontiers in pharmacology (20.10.2022)
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Journal Article
hERG potassium channel blockade by the HCN channel inhibitor bradycardic agent ivabradine
Melgari, Dario, Brack, Kieran E, Zhang, Chuan, Zhang, Yihong, El Harchi, Aziza, Mitcheson, John S, Dempsey, Christopher E, Ng, G André, Hancox, Jules C
Published in Journal of the American Heart Association (24.04.2015)
Published in Journal of the American Heart Association (24.04.2015)
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Journal Article
Analysis of α-Dystroglycan/LG Domain Binding Modes: Investigating Protein Motifs That Regulate the Affinity of Isolated LG Domains
Dempsey, Christopher E, Bigotti, Maria Giulia, Adams, Josephine C, Brancaccio, Andrea
Published in Frontiers in molecular biosciences (29.03.2019)
Published in Frontiers in molecular biosciences (29.03.2019)
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Journal Article
Structure, Location, and Lipid Perturbations of Melittin at the Membrane Interface
Hristova, Kalina, Dempsey, Christopher E., White, Stephen H.
Published in Biophysical journal (01.02.2001)
Published in Biophysical journal (01.02.2001)
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Journal Article
Voltage Sensor Gating Charge Transfer in a hERG Potassium Channel Model
Colenso, Charlotte K., Cao, Yang, Sessions, Richard B., Hancox, Jules C., Dempsey, Christopher E.
Published in Biophysical journal (18.11.2014)
Published in Biophysical journal (18.11.2014)
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Journal Article
Amphipathic antimicrobial peptides--from biophysics to therapeutics?
Dempsey, Christopher E, Hawrani, Ayman, Howe, Robin A, Walsh, Timothy R
Published in Protein and peptide letters (01.11.2010)
Published in Protein and peptide letters (01.11.2010)
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Journal Article
Dissecting Contributions to the Denaturant Sensitivities of Proteins
Dempsey, Christopher E, Piggot, Thomas J, Mason, Philip E
Published in Biochemistry (Easton) (18.01.2005)
Published in Biochemistry (Easton) (18.01.2005)
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Journal Article
Characterization of recombinant hERG K+ channel inhibition by the active metabolite of amiodarone desethyl-amiodarone
Zhang, Yi H., PhD, Cheng, Hongwei, PhD, Alexeenko, Vadim A., PhD, Dempsey, Christopher E., PhD, Hancox, Jules C., PhD
Published in Journal of electrocardiology (01.09.2010)
Published in Journal of electrocardiology (01.09.2010)
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Journal Article