Beta Cell Imaging-From Pre-Clinical Validation to First in Man Testing
Demine, Stephane, Schulte, Michael L, Territo, Paul R, Eizirik, Decio L
Published in International journal of molecular sciences (01.10.2020)
Published in International journal of molecular sciences (01.10.2020)
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Journal Article
Mitochondrial Uncoupling: A Key Controller of Biological Processes in Physiology and Diseases
Demine, Stéphane, Renard, Patricia, Arnould, Thierry
Published in Cells (Basel, Switzerland) (30.07.2019)
Published in Cells (Basel, Switzerland) (30.07.2019)
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Journal Article
Pro-inflammatory cytokines induce cell death, inflammatory responses, and endoplasmic reticulum stress in human iPSC-derived beta cells
Demine, Stéphane, Schiavo, Andrea Alex, Marín-Cañas, Sandra, Marchetti, Piero, Cnop, Miriam, Eizirik, Decio L
Published in Stem cell research & therapy (03.01.2020)
Published in Stem cell research & therapy (03.01.2020)
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Journal Article
Pancreatic β-cell tRNA hypomethylation and fragmentation link TRMT10A deficiency with diabetes
Cosentino, Cristina, Toivonen, Sanna, Diaz Villamil, Esteban, Atta, Mohamed, Ravanat, Jean-Luc, Demine, Stéphane, Schiavo, Andrea Alex, Pachera, Nathalie, Deglasse, Jean-Philippe, Jonas, Jean-Christophe, Balboa, Diego, Otonkoski, Timo, Pearson, Ewan R, Marchetti, Piero, Eizirik, Décio L, Cnop, Miriam, Igoillo-Esteve, Mariana
Published in Nucleic acids research (02.11.2018)
Published in Nucleic acids research (02.11.2018)
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Journal Article
A nanobody-based nuclear imaging tracer targeting dipeptidyl peptidase 6 to determine the mass of human beta cell grafts in mice
Demine, Stéphane, Garcia Ribeiro, Rita, Thevenet, Julien, Marselli, Lorella, Marchetti, Piero, Pattou, François, Kerr-Conte, Julie, Devoogdt, Nick, Eizirik, Decio L.
Published in Diabetologia (01.04.2020)
Published in Diabetologia (01.04.2020)
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Journal Article
Nova1 or Bim Deficiency in Pancreatic β-Cells Does Not Alter Multiple Low-Dose Streptozotocin-Induced Diabetes and Diet-Induced Obesity in Mice
Brahma, Manoja K, Xiao, Peng, Popa, Madalina, Negueruela, Javier, Vandenbempt, Valerie, Demine, Stéphane, Cardozo, Alessandra K, Gurzov, Esteban N
Published in Nutrients (01.09.2022)
Published in Nutrients (01.09.2022)
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Journal Article
Mild mitochondrial uncoupling induces HSL/ATGL‐independent lipolysis relying on a form of autophagy in 3T3‐L1 adipocytes
Demine, Stéphane, Tejerina, Silvia, Bihin, Benoît, Thiry, Marc, Reddy, Nagabushana, Renard, Patricia, Raes, Martine, Jadot, Michel, Arnould, Thierry
Published in Journal of cellular physiology (01.02.2018)
Published in Journal of cellular physiology (01.02.2018)
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Journal Article
Web Resource
A nanobody-based tracer targeting DPP6 for non-invasive imaging of human pancreatic endocrine cells
Balhuizen, Alexander, Massa, Sam, Mathijs, Iris, Turatsinze, Jean-Valery, De Vos, Jens, Demine, Stéphane, Xavier, Catarina, Villate, Olatz, Millard, Isabelle, Egrise, Dominique, Capito, Carmen, Scharfmann, Raphaël, In’t Veld, Pieter, Marchetti, Piero, Muyldermans, Serge, Goldman, Serge, Lahoutte, Tony, Bouwens, Luc, Eizirik, Decio L., Devoogdt, Nick
Published in Scientific reports (09.11.2017)
Published in Scientific reports (09.11.2017)
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Journal Article
Lipin-1 regulates cancer cell phenotype and is a potential target to potentiate rapamycin treatment
Brohée, Laura, Demine, Stéphane, Willems, Jérome, Arnould, Thierry, Colige, Alain C, Deroanne, Christophe F
Published in Oncotarget (10.05.2015)
Published in Oncotarget (10.05.2015)
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Journal Article
Web Resource
Imaging of Human Insulin Secreting Cells with Gd-DOTA-P88, a Paramagnetic Contrast Agent Targeting the Beta Cell Biomarker FXYD2γa
Demine, Stéphane, Balhuizen, Alexander, Debaille, Vinciane, Joosten, Lieke, Fereau, Maïté, Chilla, Satya Narayana Murthy, Millard, Isabelle, Scharfmann, Raphaël, Egrise, Dominique, Goldman, Serge, Marchetti, Piero, Gotthardt, Martin, Laurent, Sophie, Burtea, Carmen, Eizirik, Decio L
Published in Molecules (Basel, Switzerland) (21.08.2018)
Published in Molecules (Basel, Switzerland) (21.08.2018)
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Journal Article
HAMSAB diet ameliorates dysfunctional signaling in pancreatic islets in autoimmune diabetes
Vandenbempt, Valerie, Eski, Sema Elif, Brahma, Manoja K., Li, Ao, Negueruela, Javier, Bruggeman, Ylke, Demine, Stéphane, Xiao, Peng, Cardozo, Alessandra K., Baeyens, Nicolas, Martelotto, Luciano G., Singh, Sumeet Pal, Mariño, Eliana, Gysemans, Conny, Gurzov, Esteban N.
Published in iScience (19.01.2024)
Published in iScience (19.01.2024)
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Journal Article
Unraveling biochemical pathways affected by mitochondrial dysfunctions using metabolomic approaches
Demine, Stéphane, Reddy, Nagabushana, Renard, Patricia, Raes, Martine, Arnould, Thierry
Published in Metabolites (25.09.2014)
Published in Metabolites (25.09.2014)
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Journal Article
Different molecular mechanisms involved in spontaneous and oxidative stress-induced mitochondrial fragmentation in tripeptidyl peptidase-1 (TPP-1)-deficient fibroblasts
Van Beersel, Guillaume, Tihon, Eliane, Demine, Stéphane, Hamer, Isabelle, Jadot, Michel, Arnould, Thierry
Published in Bioscience reports (07.02.2013)
Published in Bioscience reports (07.02.2013)
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Journal Article
Mild mitochondrial uncoupling does not affect mitochondrial biogenesis but downregulates pyruvate carboxylase in adipocytes: role for triglyceride content reduction
De Pauw, Aurélia, Demine, Stéphane, Tejerina, Silvia, Dieu, Marc, Delaive, Edouard, Kel, Alexander, Renard, Patricia, Raes, Martine, Arnould, Thierry
Published in American journal of physiology: endocrinology and metabolism (01.05.2012)
Published in American journal of physiology: endocrinology and metabolism (01.05.2012)
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Journal Article
Macroautophagy and cell responses related to mitochondrial dysfunction, lipid metabolism and unconventional secretion of proteins
Demine, Stéphane, Michel, Sébastien, Vannuvel, Kayleen, Wanet, Anaïs, Renard, Patricia, Arnould, Thierry
Published in Cells (20.06.2012)
Published in Cells (20.06.2012)
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Journal Article
Book Review
25-OR: ADA Presidents' Select Abstract: Preclinical Evaluation of TYK2 Inhibitors in Type 1 Diabetes
SYED, FAROOQ, BALLEW, OLIVIA, LEE, CHIH-CHUN, RANA, JYOTI, CASTELA, ANGELA, WEAVER, STACI A., THOMAIDOU, SOFIA, DEMINE, STÉPHANE, COOMANS DE BRACHÈNE, ALEXANDRA, ALVELOS, MARIA I., CHANG, GARRICK, ORR, KARA, YAMADA, KENTARO, LIU, JING, ZALDUMBIDE, ARNAUD, SCHEUNER, DONALYN, EIZIRIK, DECIO L., EVANS-MOLINA, CARMELLA
Published in Diabetes (New York, N.Y.) (20.06.2023)
Published in Diabetes (New York, N.Y.) (20.06.2023)
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Journal Article
Pharmacological inhibition of tyrosine protein-kinase 2 reduces islet inflammation and delays type 1 diabetes onset in mice
Syed, Farooq, Ballew, Olivia, Lee, Chih-Chun, Rana, Jyoti, Krishnan, Preethi, Castela, Angela, Weaver, Staci A, Chalasani, Namratha Shivani, Thomaidou, Sofia F, Demine, Stephane, Chang, Garrick, Coomans de Brachène, Alexandra, Alvelos, Maria Ines, Marselli, Lorella, Orr, Kara, Felton, Jamie L, Liu, Jing, Marchetti, Piero, Zaldumbide, Arnaud, Scheuner, Donalyn, Eizirik, Decio L, Evans-Molina, Carmella
Published in bioRxiv (09.05.2024)
Published in bioRxiv (09.05.2024)
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Journal Article
Transcription and splicing regulation by NLRC5 shape the interferon response in human pancreatic β cells
Szymczak, Florian, Alvelos, Maria Inês, Marín-Cañas, Sandra, Castela, Ângela, Demine, Stéphane, Colli, Maikel Luis, Op de Beeck, Anne, Thomaidou, Sofia, Marselli, Lorella, Zaldumbide, Arnaud, Marchetti, Piero, Eizirik, Décio L
Published in Science advances (16.09.2022)
Published in Science advances (16.09.2022)
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Journal Article
Mild mitochondrial uncoupling does not affect mitochondrial biogenesis but downregulates pyruvate carboxylase in adipocytes: role for triglyceride content reduction
DE PAUW, Aurélia, DEMINE, Stéphane, TEJERINA, Silvia, DIEU, Marc, DELAIVE, Edouard, KEL, Alexander, RENARD, Patricia, RAES, Martine, ARNOULD, Thierry
Published in American journal of physiology: endocrinology and metabolism (2012)
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Published in American journal of physiology: endocrinology and metabolism (2012)
Journal Article