Nonameric structures of the cytoplasmic domain of FlhA and SctV in the context of the full-length protein
Kuhlen, Lucas, Johnson, Steven, Cao, Jerry, Deme, Justin C, Lea, Susan M
Published in PloS one (18.06.2021)
Published in PloS one (18.06.2021)
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Journal Article
Type 9 secretion system structures reveal a new protein transport mechanism
Lauber, Frédéric, Deme, Justin C., Lea, Susan M., Berks, Ben C.
Published in Nature (London) (01.12.2018)
Published in Nature (London) (01.12.2018)
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Journal Article
Capturing heterogeneous conformers of cobalamin riboswitch by cryo-EM
Ding, Jienyu, Deme, Justin C, Stagno, Jason R, Yu, Ping, Lea, Susan M, Wang, Yun-Xing
Published in Nucleic acids research (13.10.2023)
Published in Nucleic acids research (13.10.2023)
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Journal Article
Mechanism of lipid droplet formation by the yeast Sei1/Ldb16 Seipin complex
Klug, Yoel A., Deme, Justin C., Corey, Robin A., Renne, Mike F., Stansfeld, Phillip J., Lea, Susan M., Carvalho, Pedro
Published in Nature communications (08.10.2021)
Published in Nature communications (08.10.2021)
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Journal Article
Structure of the core of the type III secretion system export apparatus
Kuhlen, Lucas, Abrusci, Patrizia, Johnson, Steven, Gault, Joseph, Deme, Justin, Caesar, Joseph, Dietsche, Tobias, Mebrhatu, Mehari Tesfazgi, Ganief, Tariq, Macek, Boris, Wagner, Samuel, Robinson, Carol V., Lea, Susan M.
Published in Nature structural & molecular biology (01.07.2018)
Published in Nature structural & molecular biology (01.07.2018)
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Journal Article
The substrate specificity switch FlhB assembles onto the export gate to regulate type three secretion
Kuhlen, Lucas, Johnson, Steven, Zeitler, Andreas, Bäurle, Sandra, Deme, Justin C., Caesar, Joseph J. E., Debo, Rebecca, Fisher, Joseph, Wagner, Samuel, Lea, Susan M.
Published in Nature communications (10.03.2020)
Published in Nature communications (10.03.2020)
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Journal Article
The Structure of an Injectisome Export Gate Demonstrates Conservation of Architecture in the Core Export Gate between Flagellar and Virulence Type III Secretion Systems
Johnson, Steven, Kuhlen, Lucas, Deme, Justin C, Abrusci, Patrizia, Lea, Susan M
Published in mBio (25.06.2019)
Published in mBio (25.06.2019)
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Journal Article
Structural basis for antibiotic transport and inhibition in PepT2
Parker, Joanne L., Deme, Justin C., Lichtinger, Simon M., Kuteyi, Gabriel, Biggin, Philip C., Lea, Susan M., Newstead, Simon
Published in Nature communications (09.10.2024)
Published in Nature communications (09.10.2024)
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Journal Article
Structural basis of antifolate recognition and transport by PCFT
Parker, Joanne L., Deme, Justin C., Kuteyi, Gabriel, Wu, Zhiyi, Huo, Jiandong, Goldman, I. David, Owens, Raymond J., Biggin, Philip C., Lea, Susan M., Newstead, Simon
Published in Nature (London) (01.07.2021)
Published in Nature (London) (01.07.2021)
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Journal Article
Molecular structure of the intact bacterial flagellar basal body
Johnson, Steven, Furlong, Emily J., Deme, Justin C., Nord, Ashley L., Caesar, Joseph J. E., Chevance, Fabienne F. V., Berry, Richard M., Hughes, Kelly T., Lea, Susan M.
Published in Nature microbiology (01.06.2021)
Published in Nature microbiology (01.06.2021)
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Journal Article
Three small partner proteins facilitate the type VII-dependent secretion of an antibacterial nuclease
Yang, Yaping, Boardman, Eleanor, Deme, Justin, Alcock, Felicity, Lea, Susan, Palmer, Tracy
Published in mBio (31.10.2023)
Published in mBio (31.10.2023)
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Journal Article
An inhibitor of complement C5 provides structural insights into activation
Reichhardt, Martin P., Johnson, Steven, Tang, Terence, Morgan, Thomas, Tebeka, Nchimunya, Popitsch, Niko, Deme, Justin C., Jore, Matthijs M., Lea, Susan M.
Published in Proceedings of the National Academy of Sciences - PNAS (07.01.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (07.01.2020)
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Journal Article
Structures of the stator complex that drives rotation of the bacterial flagellum
Deme, Justin C., Johnson, Steven, Vickery, Owen, Aron, Amy, Monkhouse, Holly, Griffiths, Thomas, James, Rory Hennell, Berks, Ben C., Coulton, James W., Stansfeld, Phillip J., Lea, Susan M.
Published in Nature microbiology (01.12.2020)
Published in Nature microbiology (01.12.2020)
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Journal Article
Structures of the Type IX Secretion/Gliding Motility Motor from across the Phylum Bacteroidetes
Hennell James, Rory, Deme, Justin C, Hunter, Alicia, Berks, Ben C, Lea, Susan M
Published in mBio (28.06.2022)
Published in mBio (28.06.2022)
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Journal Article
Symmetry mismatch in the MS-ring of the bacterial flagellar rotor explains the structural coordination of secretion and rotation
Johnson, Steven, Fong, Yu Hang, Deme, Justin C., Furlong, Emily J., Kuhlen, Lucas, Lea, Susan M.
Published in Nature microbiology (01.07.2020)
Published in Nature microbiology (01.07.2020)
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Journal Article
A type VII-secreted lipase toxin with reverse domain arrangement
Garrett, Stephen R., Mietrach, Nicole, Deme, Justin, Bitzer, Alina, Yang, Yaping, Ulhuq, Fatima R., Kretschmer, Dorothee, Heilbronner, Simon, Smith, Terry K., Lea, Susan M., Palmer, Tracy
Published in Nature communications (19.12.2023)
Published in Nature communications (19.12.2023)
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Journal Article
Delineation of functional subdomains of Huntingtin protein and their interaction with HAP40
Alteen, Matthew G., Deme, Justin C., Alvarez, Claudia P., Loppnau, Peter, Hutchinson, Ashley, Seitova, Alma, Chandrasekaran, Renu, Silva Ramos, Eduardo, Secker, Christopher, Alqazzaz, Mona, Wanker, Erich E., Lea, Susan M., Arrowsmith, Cheryl H., Harding, Rachel J.
Published in Structure (London) (07.09.2023)
Published in Structure (London) (07.09.2023)
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Journal Article
Molecular Basis for Bordetella pertussis Interference with Complement, Coagulation, Fibrinolytic, and Contact Activation Systems: the Cryo-EM Structure of the Vag8-C1 Inhibitor Complex
Dhillon, Arun, Deme, Justin C, Furlong, Emily, Roem, Dorina, Jongerius, Ilse, Johnson, Steven, Lea, Susan M
Published in mBio (23.03.2021)
Published in mBio (23.03.2021)
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Journal Article