Search Results - "Demattei, John" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Preclinical Development of the Class-I-Selective Histone Deacetylase Inhibitor OKI-179 for the Treatment of Solid Tumors

Preclinical Development of the Class-I-Selective Histone Deacetylase Inhibitor OKI-179 for the Treatment of Solid Tumors

by Diamond, Jennifer R, Pitts, Todd M, Ungermannova, Dana, Nasveschuk, Christopher G, Zhang, Gan, Phillips, Andrew J, Bagby, Stacey M, Pafford, Jessica, Yacob, Betelehem W, Newton, Timothy P, Tentler, John J, Gittleman, Brian, Hartman, Sarah J, DeMattei, John A, Winkler, James D, Wendt, Michael K, Schiemann, William P, Eckhardt, S Gail, Liu, Xuedong, Piscopio, Anthony D
Published in Molecular cancer therapeutics (01.03.2022)

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Journal Article

First-in-Human Dose-Escalation Study of the Novel Oral Depsipeptide Class I-Targeting HDAC Inhibitor Bocodepsin (OKI-179) in Patients with Advanced Solid Tumors

First-in-Human Dose-Escalation Study of the Novel Oral Depsipeptide Class I-Targeting HDAC Inhibitor Bocodepsin (OKI-179) in Patients with Advanced Solid Tumors

by Schreiber, Anna R, Kagihara, Jodi A, Corr, Bradley R, Davis, S Lindsey, Lieu, Christopher, Kim, Sunnie S, Jimeno, Antonio, Camidge, D Ross, Williams, Jud, Heim, Amy M, Martin, Anne, DeMattei, John A, Holay, Nisha, Triplett, Todd A, Eckhardt, S Gail, Litwiler, Kevin, Winkler, James, Piscopio, Anthony D, Diamond, Jennifer R
Published in Cancers (23.12.2023)

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Preparation of Pyrrolidine-Based PDE4 Inhibitors via Enantioselective Conjugate Addition of α-Substituted Malonates to Aromatic Nitroalkenes

Preparation of Pyrrolidine-Based PDE4 Inhibitors via Enantioselective Conjugate Addition of α-Substituted Malonates to Aromatic Nitroalkenes

by Nichols, Paul J, DeMattei, John A, Barnett, Bradley R, LeFur, Nicole A, Chuang, Tsung-Hsun, Piscopio, Anthony D, Koch, Kevin
Published in Organic letters (30.03.2006)

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Journal Article

Complete Relative Stereochemistry of Maitotoxin

Complete Relative Stereochemistry of Maitotoxin

by Zheng, Wanjun, DeMattei, John A, Wu, Jiang-Ping, Duan, James J.-W, Cook, Laura R, Oinuma, Hitoshi, Kishi, Yoshito
Published in Journal of the American Chemical Society (28.08.1996)

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A highly diastereoselective vinylogous Mannich condensation and 1,4-conjugate addition of ( Z)-propenyl cuprate in the synthesis of an influenza neuraminidase inhibitor

A highly diastereoselective vinylogous Mannich condensation and 1,4-conjugate addition of ( Z)-propenyl cuprate in the synthesis of an influenza neuraminidase inhibitor

by Barnes, David M., Bhagavatula, Lakshmi, DeMattei, John, Gupta, Ashok, Hill, David R., Manna, Sukumar, McLaughlin, Maureen A., Nichols, Paul, Premchandran, Ramiya, Rasmussen, Michael W., Tian, Zhenping, Wittenberger, Steven J.
Published in Tetrahedron: asymmetry (01.11.2003)

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A Scaleable Synthesis of Fiduxosin

A Scaleable Synthesis of Fiduxosin

by Haight, Anthony R, Bailey, Anne E, Baker, William S, Cain, Michael H, Copp, Richard R, DeMattei, John A, Ford, Kelley L, Henry, Rodger F, Hsu, Margaret C, Keyes, Robert F, King, Steven A, McLaughlin, Maureen A, Melcher, Laura M, Nadler, William R, Oliver, Patricia A, Parekh, Shyamal I, Patel, Hemant H, Seif, Louis S, Staeger, Mike A, Wayne, Gregory S, Wittenberger, Steven J, Zhang, Weijiang
Published in Organic process research & development (01.11.2004)

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Allylation of Erythromycin Derivatives: Introduction of Allyl Substituents into Highly Hindered Alcohols

Allylation of Erythromycin Derivatives: Introduction of Allyl Substituents into Highly Hindered Alcohols

by Stoner, Eric J, Peterson, Matthew J, Allen, Michael S, DeMattei, John A, Haight, Anthony R, Leanna, M. Robert, Patel, Subhash R, Plata, Daniel J, Premchandran, Ramiya H, Rasmussen, Michael
Published in Journal of organic chemistry (14.11.2003)

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Journal Article

Asymmetric Synthesis of Calyculin C. 1. Synthesis of the C1−C25 Fragment

Asymmetric Synthesis of Calyculin C. 1. Synthesis of the C1−C25 Fragment

by Scarlato, Gerard R, DeMattei, John A, Chong, Lee S, Ogawa, Anthony K, Lin, Mavis R, Armstrong, Robert W
Published in Journal of organic chemistry (06.09.1996)

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Abstract B007: OKI-179 is a novel, oral, class I specific histone deacetylase inhibitor in phase 1 clinical trials

Abstract B007: OKI-179 is a novel, oral, class I specific histone deacetylase inhibitor in phase 1 clinical trials

by Diamond, Jennifer R, Kagihara, Jodi A, Liu, Xuedong, Gordon, Gilad, Heim, Amy M, Winkler, James, DeMattei, John A, Piscopio, Anthony D, Eckhardt, S. Gail
Published in Molecular cancer therapeutics (01.12.2019)

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Journal Article

Asymmetric Synthesis of Calyculin C. 2. Synthesis of the C26−C37 Fragment and Model Wittig Couplings

Asymmetric Synthesis of Calyculin C. 2. Synthesis of the C26−C37 Fragment and Model Wittig Couplings

by Ogawa, Anthony K, DeMattei, John A, Scarlato, Gerard R, Tellew, John E, Chong, Lee S, Armstrong, Robert W
Published in Journal of organic chemistry (06.09.1996)

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Journal Article

Synthesis of the C-13 Side Chain Precursors of the 9-Dihydrotaxane Analogue ABT-271

Synthesis of the C-13 Side Chain Precursors of the 9-Dihydrotaxane Analogue ABT-271

by Leanna, M. Robert, DeMattei, John A, Li, Wenke, Nichols, Paul J, Rasmussen, Michael, Morton, Howard E
Published in Organic letters (16.11.2000)

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Phase 1 study of OKI-179, an oral class 1-selective depsipeptide HDAC inhibitor, in patients with advanced solid tumors: Final results

Phase 1 study of OKI-179, an oral class 1-selective depsipeptide HDAC inhibitor, in patients with advanced solid tumors: Final results

by Kagihara, Jodi A., Corr, Bradley, Pacheco, Jose Maria, Davis, S. Lindsey, Lieu, Christopher Hanyoung, Kim, Sunnie S., Jimeno, Antonio, Heim, Amy M., DeMattei, John A., Gordon, Gilad, Triplett, Todd A., Eckhardt, S. Gail, Winkler, James D., Piscopio, Anthony D., Diamond, Jennifer Robinson
Published in Journal of clinical oncology (20.05.2021)

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Journal Article

An Efficient Synthesis of the Taxane-Derived Anticancer Agent ABT-271

An Efficient Synthesis of the Taxane-Derived Anticancer Agent ABT-271

by DeMattei, John A., Leanna, M. Robert, Li, Wenke, Nichols, Paul J., Rasmussen, Michael W., Morton, Howard E.
Published in Journal of organic chemistry (18.05.2001)

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Journal Article

PROCESS FOR MAKING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

PROCESS FOR MAKING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

by ROEPER STEFANIE, RYAN MICHAEL P, BOTFIELD MARTYN C, TRUDEAU MARTIN, KRUEGER BRIAN R, YAP DAHRIKA MILFRED LAO, ZLOKARNIK GREGOR, VAN GOOR FREDERICK F, DEMATTEI JOHN, LOOKER ADAM R, GROOTENHUIS PETER D.J, NEUBERT LANGILLE BOBBIANNA
Year of Publication 27.04.2018

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Patent

Asymmetric Synthesis of Calyculin C. 2. Synthesis of the C(26)-C(37) Fragment and Model Wittig Couplings

Asymmetric Synthesis of Calyculin C. 2. Synthesis of the C(26)-C(37) Fragment and Model Wittig Couplings

by Ogawa, Anthony K., DeMattei, John A., Scarlato, Gerard R., Tellew, John E., Chong, Lee S., Armstrong, Robert W.
Published in Journal of organic chemistry (06.09.1996)

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Journal Article

Asymmetric Synthesis of Calyculin C. 1. Synthesis of the C(1)-C(25) Fragment

Asymmetric Synthesis of Calyculin C. 1. Synthesis of the C(1)-C(25) Fragment

by Scarlato, Gerard R., DeMattei, John A., Chong, Lee S., Ogawa, Anthony K., Lin, Mavis R., Armstrong, Robert W.
Published in Journal of organic chemistry (06.09.1996)

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Journal Article

PROCESS FOR MAKING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

PROCESS FOR MAKING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR

by ROEPER STEFANIE, RYAN MICHAEL P, BOTFIELD MARTYN C, TRUDEAU MARTIN, KRUEGER BRIAN R, YAP DAHRIKA MILFRED LAO, ZLOKARNIK GREGOR, VAN GOOR FREDERICK F, DEMATTEI JOHN, LOOKER ADAM R, GROOTENHUIS PETER D.J, NEUBERT LANGILLE BOBBIANNA
Year of Publication 19.04.2017

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Patent

ALKYL CHAIN MODIFIED IMIDAZOQUINOLINE DERIVATIVES AS TLR7/8 AGONISTS AND USES THEREOF

ALKYL CHAIN MODIFIED IMIDAZOQUINOLINE DERIVATIVES AS TLR7/8 AGONISTS AND USES THEREOF

by KACHURA, Melissa, A, KIWAN, Radwan, CHIPMAN, Stewart, D, DEMATTEI, John
Year of Publication 18.10.2023

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Patent

ALKYL CHAIN MODIFIED IMIDAZOQUINOLINE DERIVATIVES AS TLR7/8 AGONISTS AND USES THEREOF

ALKYL CHAIN MODIFIED IMIDAZOQUINOLINE DERIVATIVES AS TLR7/8 AGONISTS AND USES THEREOF

by KACHURA, Melissa, A, KIWAN, Radwan, CHIPMAN, Stewart, D, DEMATTEI, John
Year of Publication 11.10.2023

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Patent

PROCESS FOR PREPARING BENZIMIDAZOLE COMPOUNDS

PROCESS FOR PREPARING BENZIMIDAZOLE COMPOUNDS

by PEETERS KOEN, EVANS MATTHEW CHARLES, LILLEY TIMOTHY JOHN, LEONARD JOHN, PISCOPIO ANTHONY D, FORD JAMES GAIR, DEMATTEI JOHN, SHAKYA SAGAR, HACHE BRUNO P, POINTON SIMON MARK
Year of Publication 03.01.2014

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Patent

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