Computational design of a specific heavy chain/κ light chain interface for expressing fully IgG bispecific antibodies
Froning, K. J., Leaver‐Fay, A., Wu, X., Phan, S., Gao, L., Huang, F., Pustilnik, A., Bacica, M., Houlihan, K., Chai, Q., Fitchett, J. R., Hendle, J., Kuhlman, B., Demarest, S. J.
Published in Protein science (01.10.2017)
Published in Protein science (01.10.2017)
Get full text
Journal Article
Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators
Wright, Peter E, Demarest, Stephen J, Martinez-Yamout, Maria, Chung, John, Chen, Hongwu, Xu, Wei, Dyson, H. Jane, Evans, Ronald M
Published in Nature (London) (31.01.2002)
Published in Nature (London) (31.01.2002)
Get full text
Journal Article
A Comparative Study of Peptide Models of the α-Domain of α-Lactalbumin, Lysozyme, and α-Lactalbumin/Lysozyme Chimeras Allows the Elucidation of Critical Factors That Contribute to the Ability to Form Stable Partially Folded States
Demarest, Stephen J, Zhou, Shui-Qin, Robblee, James, Fairman, Robert, Chu, Benjamin, Raleigh, Daniel P
Published in Biochemistry (Easton) (20.02.2001)
Published in Biochemistry (Easton) (20.02.2001)
Get full text
Journal Article
Defining the core structure of the alpha-lactalbumin molten globule state
Demarest, S J, Boice, J A, Fairman, R, Raleigh, D P
Published in Journal of molecular biology (19.11.1999)
Published in Journal of molecular biology (19.11.1999)
Get full text
Journal Article
A broad range of Fab stabilities within a host of therapeutic IgGs
Garber, Ellen, Demarest, Stephen J.
Published in Biochemical and biophysical research communications (13.04.2007)
Published in Biochemical and biophysical research communications (13.04.2007)
Get full text
Journal Article
Solution structure of a peptide model of a region important for the folding of α-lactalbumin provides evidence for the formation of nonnative structure in the denatured state
Demarest, Stephen J., Raleigh, Daniel P.
Published in Proteins, structure, function, and bioinformatics (01.02.2000)
Published in Proteins, structure, function, and bioinformatics (01.02.2000)
Get full text
Journal Article
Computational design of a specific heavy chain/[kappa] light chain interface for expressing fully IgG bispecific antibodies
Froning, K J, Leaver-Fay, A, Wu, X, Phan, S, Gao, L, Huang, F, Pustilnik, A, Bacica, M, Houlihan, K, Chai, Q, Fitchett, J R, Hendle, J, Kuhlman, B, Demarest, S J
Published in Protein science (01.10.2017)
Published in Protein science (01.10.2017)
Get full text
Journal Article
Computational design of a specific heavy chain/κ light chain interface for expressing fully IgG bispecific antibodies: Computational Design of a novel C H 1/Cκ interface
Froning, K. J., Leaver-Fay, A., Wu, X., Phan, S., Gao, L., Huang, F., Pustilnik, A., Bacica, M., Houlihan, K., Chai, Q., Fitchett, J. R., Hendle, J., Kuhlman, B., Demarest, S. J.
Published in Protein science (31.07.2017)
Published in Protein science (31.07.2017)
Get full text
Journal Article
Engineering stability into Escherichia coli secreted Fabs leads to increased functional expression
Demarest, Stephen J., Chen, Gang, Kimmel, Bruce E., Gustafson, David, Wu, Jane, Salbato, Jared, Poland, John, Elia, Marikka, Tan, Xuqiu, Wong, Ken, Short, Jay, Hansen, Geneviève
Published in Protein engineering, design and selection (01.07.2006)
Published in Protein engineering, design and selection (01.07.2006)
Get full text
Journal Article
Optimization of the Antibody CH3 Domain by Residue Frequency Analysis of IgG Sequences
Demarest, Stephen J., Rogers, Jeff, Hansen, Geneviève
Published in Journal of molecular biology (02.01.2004)
Published in Journal of molecular biology (02.01.2004)
Get full text
Journal Article
Local interactions and the role of the 6-120 disulfide bond in α-lactalbumin: implications for formation of the molten globule state
Moriarty, Daniel F., Demarest, Stephen J., Robblee, James, Fairman, Robert, Raleigh, Daniel P.
Published in Biochimica et biophysica acta (03.01.2000)
Published in Biochimica et biophysica acta (03.01.2000)
Get full text
Journal Article
Structural Characterization of the Cell Wall Binding Domains of Clostridium difficile Toxins A and B; Evidence that Ca super(2) super(+) Plays a Role in Toxin A Cell Surface Association
Demarest, S J, Salbato, J, Elia, M, Zhong, J, Morrow, T, Holland, T, Kline, K, Woodnutt, G, Kimmel, B E, Hansen, G
Published in Journal of molecular biology (11.03.2005)
Published in Journal of molecular biology (11.03.2005)
Get full text
Journal Article
A protein dissection study demonstrates that two specific hydrophobic clusters play a key role in stabilizing the core structure of the molten globule state of human α-lactalbumin
Demarest, Stephen J., Horng, Jia-Cherng, Raleigh, Daniel P.
Published in Proteins, structure, function, and bioinformatics (01.02.2001)
Published in Proteins, structure, function, and bioinformatics (01.02.2001)
Get full text
Journal Article
Antibody therapeutics, antibody engineering, and the merits of protein stability
Demarest, Stephen J, Glaser, Scott M
Published in Current opinion in drug discovery & development (01.09.2008)
Get more information
Published in Current opinion in drug discovery & development (01.09.2008)
Journal Article
Optimization of the antibody C(H)3 domain by residue frequency analysis of IgG sequences
Demarest, Stephen J, Rogers, Jeff, Hansen, Geneviève
Published in Journal of molecular biology (02.01.2004)
Published in Journal of molecular biology (02.01.2004)
Get full text
Journal Article
Structural characterization of the cell wall binding domains of Clostridium difficile toxins A and B; evidence that Ca2+ plays a role in toxin A cell surface association
Demarest, Stephen J, Salbato, Jared, Elia, Marikka, Zhong, Jingping, Morrow, Theresa, Holland, Trevin, Kline, Katie, Woodnutt, Gary, Kimmel, Bruce E, Hansen, Geneviève
Published in Journal of molecular biology (11.03.2005)
Published in Journal of molecular biology (11.03.2005)
Get full text
Journal Article
pH-dependent stability of the human α-lactalbumin molten globule state: Contrasting roles of the 6-120 disulfide and the β-subdomain at low and neutral pH
Horng, Jia-Cherng, Demarest, Stephen J., Raleigh, Daniel P.
Published in Proteins, structure, function, and bioinformatics (01.08.2003)
Published in Proteins, structure, function, and bioinformatics (01.08.2003)
Get full text
Journal Article