BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc
Delmore, Jake E., Issa, Ghayas C., Lemieux, Madeleine E., Rahl, Peter B., Shi, Junwei, Jacobs, Hannah M., Kastritis, Efstathios, Gilpatrick, Timothy, Paranal, Ronald M., Qi, Jun, Chesi, Marta, Schinzel, Anna C., McKeown, Michael R., Heffernan, Timothy P., Vakoc, Christopher R., Bergsagel, P. Leif, Ghobrial, Irene M., Richardson, Paul G., Young, Richard A., Hahn, William C., Anderson, Kenneth C., Kung, Andrew L., Bradner, James E., Mitsiades, Constantine S.
Published in Cell (16.09.2011)
Published in Cell (16.09.2011)
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Journal Article
Molecular and cellular effects of NEDD8-activating enzyme inhibition in myeloma
McMillin, Douglas W, Jacobs, Hannah M, Delmore, Jake E, Buon, Leutz, Hunter, Zachary R, Monrose, Val, Yu, Jie, Smith, Peter G, Richardson, Paul G, Anderson, Kenneth C, Treon, Steven P, Kung, Andrew L, Mitsiades, Constantine S
Published in Molecular cancer therapeutics (01.04.2012)
Published in Molecular cancer therapeutics (01.04.2012)
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Journal Article
Bcl-2 Overexpression in Thyroid Carcinoma Cells Increases Sensitivity to Bcl-2 Homology 3 Domain Inhibition
Mitsiades, Constantine S., Hayden, Patrick, Kotoula, Vassiliki, McMillin, Douglas W., McMullan, Ciaran, Negri, Joseph, Delmore, Jake E., Poulaki, Vassiliki, Mitsiades, Nicholas
Published in The journal of clinical endocrinology and metabolism (01.12.2007)
Published in The journal of clinical endocrinology and metabolism (01.12.2007)
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Journal Article
Temporal Dynamics of Tumor-Microenvironment Interaction and Treatment Responses Revealed through Time-Lapse Compartment-Specific Bioluminescence Imaging: Translational implications
Dhimolea, Eugen, King, Emily, Kastritis, Efstathios, McMillin, Douglas W., Delmore, Jake E., Negri, Joseph M., Jacobs, Hannah M., Hayes, Catriona A., Sheffer, Michal, Hu, Yiguo, Sarkar, Subhashis, Groen, Richard W.J., Bariteau, Megan A., Aftab, Blake T., Mitsiades, Constantine S.
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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Journal Article
Cell Non-Autonomous Modulation Of Tumor Cell Responses To Pharmacological Inhibition Of The Proteasome
Dhimolea, Eugen, Groen, Richard W.J., Hayes, Catriona A., Jakubikova, Jana, Megan, Bariteau, Delmore, Jake E., Jacobs, Hannah M., Marin, Julio-Cesar, Della Penna, Gregory, McMillin, Douglas W., Acuna, Ana, Lawasut, Panisinee, Kohl, Nancy, Mitsiades, Constantine S.
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
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Journal Article
In Vitro Anti-Myeloma Activity of the Multitargeted Kinase Inhibitor Midostaurin in the Context of Heterotypic Cocultures of Myeloma Cells with Nonmalignant Microenvironmental Accessory Cells
Lawasut, Panisinee, Jacobs, Hannah M., Delmore, Jake E, Negri, Joseph, McMillin, Douglas W., Weisberg, Ellen L, Griffin, James D., Richardson, Paul G., Anderson, Kenneth C, Mitsiades, Constantine S.
Published in Blood (18.11.2011)
Published in Blood (18.11.2011)
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Journal Article
Cells of the Osteoblast Lineage Confer Myeloma Cell Resistance to Established and Investigational Therapeutic Agents
Hayes, Catriona A., Dowling, Paul, Groen, Richard W.J., McMillin, Douglas W., Delmore, Jake E., Jacobs, Hannah M., van de Donk, Niels W.C.J., Dhimolea, Eugen, Richardson, Paul G., Anderson, Kenneth C., Clynes, Martin, O'Gorman, Peter, Mitsiades, Constantine S.
Published in Blood (16.11.2012)
Published in Blood (16.11.2012)
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Journal Article
Tumor Cell-Dependent Differences in Stroma-Induced Changes to Bortezomib Sensitivity
Dhimolea, Eugen, Jakubikova, Jana, Groen, Richard W.J., Delmore, Jake E., Jacobs, Hannah M., McMilllin, Douglas W., Acuña-Villaorduña, Ana, Hayes, Catriona A., Lawasut, Panisinee, Mitsiades, Constantine S.
Published in Blood (16.11.2012)
Published in Blood (16.11.2012)
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Journal Article
Inhibition of c-Myc Expression and Function in Hematologic Malignancies
Issa, Ghayas C, Delmore, Jake E, McKeown, Michael R, Lemieux, Madeleine E, Rahl, Peter B, Jacobs, Hannah M., Kastritis, Efstathios, Gilpatrick, Timothy, Paranal, Ronald M, Qi, Jun, Shi, Junwei, Chesi, Marta, Schinzel, Anna C., Vakoc, Christopher R., Bergsagel, P.Leif, Richardson, Paul G., Young, Richard, Hahn, William C., Ghobrial, Irene M., Anderson, Kenneth C, Kung, Andrew L., Mitsiades, Constantine S., Bradner, James E
Published in Blood (18.11.2011)
Published in Blood (18.11.2011)
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Journal Article
Proteomic Characterization of An Isogenic Multiple Myeloma Cell Line Model of Bortezomib Resistance
Hayes, Catriona A., Dowling, Paul, Negri, Joseph, Henry, Michael, Buon, Leutz, Jakubikova, Jana, Delmore, Jake E, McMillin, Douglas W., Klippel, Steffen, Jacobs, Hannah M., van de Donk, Niels W.C.J., Dhimolea, Eugen, Lawasut, Panisinee, Richardson, Paul G., Anderson, Kenneth C., Clynes, Martin, Gorman, Peter O, Mitsiades, Constantine S.
Published in Blood (18.11.2011)
Published in Blood (18.11.2011)
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Journal Article
Proteasome Inhibitors Sensitize Myeloma Cells to T Cell-Mediated Killing
van de Donk, Niels W.C.J., Lokhorst, Henk M., Emmelot, Maarten, Aarts-Riemens, Tineke, McMillin, Douglas W., Gorgun, Gullu, Klippel, Steffen, Dhimolea, Eugen, Jakubikova, Jana, Hayes, Catriona A., Lawasut, Panisinee, Delmore, Jake E, Munshi, Nikhil C., Richardson, Paul G., Anderson, Kenneth C., Mitsiades, Constantine S., Mutis, Tuna
Published in Blood (18.11.2011)
Published in Blood (18.11.2011)
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Journal Article