Nicotinamide riboside is uniquely and orally bioavailable in mice and humans
Trammell, Samuel A. J., Schmidt, Mark S., Weidemann, Benjamin J., Redpath, Philip, Jaksch, Frank, Dellinger, Ryan W., Li, Zhonggang, Abel, E. Dale, Migaud, Marie E., Brenner, Charles
Published in Nature communications (10.10.2016)
Published in Nature communications (10.10.2016)
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Journal Article
Loss of NAD Homeostasis Leads to Progressive and Reversible Degeneration of Skeletal Muscle
Frederick, David W., Loro, Emanuele, Liu, Ling, Davila, Antonio, Chellappa, Karthikeyani, Silverman, Ian M., Quinn, William J., Gosai, Sager J., Tichy, Elisia D., Davis, James G., Mourkioti, Foteini, Gregory, Brian D., Dellinger, Ryan W., Redpath, Philip, Migaud, Marie E., Nakamaru-Ogiso, Eiko, Rabinowitz, Joshua D., Khurana, Tejvir S., Baur, Joseph A.
Published in Cell metabolism (09.08.2016)
Published in Cell metabolism (09.08.2016)
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Journal Article
Nicotinamide riboside and pterostilbene reduces markers of hepatic inflammation in NAFLD: A double-blind, placebo-controlled clinical trial
Dellinger, Ryan W, Holmes, Holly E, Hu-Seliger, Tina, Butt, Rodney W, Harrison, Stephen A, Mozaffarian, Dariush, Chen, Oliver, Guarente, Leonard
Published in Hepatology (Baltimore, Md.) (01.09.2023)
Published in Hepatology (Baltimore, Md.) (01.09.2023)
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Journal Article
Nicotinamide adenine dinucleotide biosynthesis promotes liver regeneration
Mukherjee, Sarmistha, Chellappa, Karthikeyani, Moffitt, Andrea, Ndungu, Joan, Dellinger, Ryan W., Davis, James G., Agarwal, Beamon, Baur, Joseph A.
Published in Hepatology (Baltimore, Md.) (01.02.2017)
Published in Hepatology (Baltimore, Md.) (01.02.2017)
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Journal Article
Pterostilbene in Cancer Therapy
Obrador, Elena, Salvador-Palmer, Rosario, Jihad-Jebbar, Ali, López-Blanch, Rafael, Dellinger, Thanh H, Dellinger, Ryan W, Estrela, José M
Published in Antioxidants (21.03.2021)
Published in Antioxidants (21.03.2021)
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Journal Article
Efficacy and tolerability of EH301 for amyotrophic lateral sclerosis: a randomized, double-blind, placebo-controlled human pilot study
de la Rubia, JosÉ E., Drehmer, Eraci, Platero, JosÉ L., Benlloch, MarÍa, Caplliure-Llopis, Jordi, Villaron-Casales, Carlos, de Bernardo, Nieves, AlarcÓn, Jorge, Fuente, Cristian, Carrera, Sandra, Sancho, David, GarcÍa-Pardo, Pilar, Pascual, Raquel, JuÁrez, Marta, Cuerda-Ballester, María, Forner, Alfonso, Sancho-Castillo, Sandra, Barrios, Carlos, Obrador, Elena, Marchio, Patricia, Salvador, Rosario, Holmes, Holly E., Dellinger, Ryan W., Guarente, Leonard, Estrela, José M.
Published in Amyotrophic lateral sclerosis and frontotemporal degeneration (02.01.2019)
Published in Amyotrophic lateral sclerosis and frontotemporal degeneration (02.01.2019)
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Journal Article
Combination of natural polyphenols with a precursor of NAD+ and a TLR2/6 ligand lipopeptide protects mice against lethal γ radiation
Obrador, Elena, Salvador-Palmer, Rosario, Pellicer, Blanca, López-Blanch, Rafael, Sirerol, J. Antoni, Villaescusa, Juan I., Montoro, Alegría, Dellinger, Ryan W., Estrela, José M.
Published in Journal of advanced research (01.03.2023)
Published in Journal of advanced research (01.03.2023)
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Journal Article
A randomized placebo-controlled trial of nicotinamide riboside and pterostilbene supplementation in experimental muscle injury in elderly individuals
Jensen, Jonas Brorson, Dollerup, Ole L., Møller, Andreas B., Billeskov, Tine B., Dalbram, Emilie, Chubanava, Sabina, Damgaard, Mads V., Dellinger, Ryan W., Trošt, Kajetan, Moritz, Thomas, Ringgaard, Steffen, Møller, Niels, Treebak, Jonas T., Farup, Jean, Jessen, Niels
Published in JCI insight (10.10.2022)
Published in JCI insight (10.10.2022)
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Journal Article
Intravenous nicotinamide riboside elevates mouse skeletal muscle NAD+ without impacting respiratory capacity or insulin sensitivity
Damgaard, Mads V., Nielsen, Thomas S., Basse, Astrid L., Chubanava, Sabina, Trost, Kajetan, Moritz, Thomas, Dellinger, Ryan W., Larsen, Steen, Treebak, Jonas T.
Published in iScience (18.02.2022)
Published in iScience (18.02.2022)
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Journal Article
NAD + Precursors and Antioxidants for the Treatment of Amyotrophic Lateral Sclerosis
Obrador, Elena, Salvador-Palmer, Rosario, López-Blanch, Rafael, Dellinger, Ryan W, Estrela, José M
Published in Biomedicines (12.08.2021)
Published in Biomedicines (12.08.2021)
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Journal Article
Anti-cancer drugs elicit re-expression of UDP-glucuronosyltransferases in melanoma cells
Dellinger, Ryan W, Matundan, Harry H, Ahmed, Amelia S, Duong, Priscilla H, Meyskens, Jr, Frank L
Published in PloS one (22.10.2012)
Published in PloS one (22.10.2012)
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Journal Article
Glucuronidation of Active Tamoxifen Metabolites by the Human UDP Glucuronosyltransferases
Sun, Dongxiao, Sharma, Arun K, Dellinger, Ryan W, Blevins-Primeau, Andrea S, Balliet, Renee M, Chen, Gang, Boyiri, Telih, Amin, Shantu, Lazarus, Philip
Published in Drug metabolism and disposition (01.11.2007)
Published in Drug metabolism and disposition (01.11.2007)
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Journal Article
Glucuronidation of Tobacco-Specific Nitrosamines by UGT2B10
Chen, Gang, Dellinger, Ryan W, Sun, Dongxiao, Spratt, Thomas E, Lazarus, Philip
Published in Drug metabolism and disposition (01.05.2008)
Published in Drug metabolism and disposition (01.05.2008)
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Journal Article
Repeat dose NRPT (nicotinamide riboside and pterostilbene) increases NAD+ levels in humans safely and sustainably: a randomized, double-blind, placebo-controlled study
Dellinger, Ryan W., Santos, Santiago Roel, Morris, Mark, Evans, Mal, Alminana, Dan, Guarente, Leonard, Marcotulli, Eric
Published in npj aging and mechanisms of disease (24.11.2017)
Published in npj aging and mechanisms of disease (24.11.2017)
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Journal Article
Oxidative stress and antioxidants in the pathophysiology of malignant melanoma
Obrador, Elena, Liu-Smith, Feng, Dellinger, Ryan W., Salvador, Rosario, Meyskens, Frank L., Estrela, José M.
Published in Biological chemistry (24.04.2019)
Published in Biological chemistry (24.04.2019)
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Journal Article
Polyphenolic Phytochemicals in Cancer Prevention and Therapy: Bioavailability versus Bioefficacy
Estrela, José M., Mena, Salvador, Obrador, Elena, Benlloch, María, Castellano, Gloria, Salvador, Rosario, Dellinger, Ryan W.
Published in Journal of medicinal chemistry (14.12.2017)
Published in Journal of medicinal chemistry (14.12.2017)
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Journal Article
Functional Characterization of Low-Prevalence Missense Polymorphisms in the UDP-Glucuronosyltransferase 1A9 Gene
Olson, Kristine C, Dellinger, Ryan W, Zhong, Qing, Sun, Dongxiao, Amin, Shantu, Spratt, Thomas E, Lazarus, Philip
Published in Drug metabolism and disposition (01.10.2009)
Published in Drug metabolism and disposition (01.10.2009)
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