Nicotinamide riboside is uniquely and orally bioavailable in mice and humans
Trammell, Samuel A J, Schmidt, Mark S, Weidemann, Benjamin J, Redpath, Philip, Jaksch, Frank, Dellinger, Ryan W, Li, Zhonggang, Abel, E Dale, Migaud, Marie E, Brenner, Charles
Published in Nature communications (10.10.2016)
Published in Nature communications (10.10.2016)
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Journal Article
Loss of NAD Homeostasis Leads to Progressive and Reversible Degeneration of Skeletal Muscle
Frederick, David W., Loro, Emanuele, Liu, Ling, Davila, Antonio, Chellappa, Karthikeyani, Silverman, Ian M., Quinn, William J., Gosai, Sager J., Tichy, Elisia D., Davis, James G., Mourkioti, Foteini, Gregory, Brian D., Dellinger, Ryan W., Redpath, Philip, Migaud, Marie E., Nakamaru-Ogiso, Eiko, Rabinowitz, Joshua D., Khurana, Tejvir S., Baur, Joseph A.
Published in Cell metabolism (09.08.2016)
Published in Cell metabolism (09.08.2016)
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Journal Article
Nicotinamide riboside and pterostilbene reduces markers of hepatic inflammation in NAFLD: A double-blind, placebo-controlled clinical trial
Dellinger, Ryan W, Holmes, Holly E, Hu-Seliger, Tina, Butt, Rodney W, Harrison, Stephen A, Mozaffarian, Dariush, Chen, Oliver, Guarente, Leonard
Published in Hepatology (Baltimore, Md.) (01.09.2023)
Published in Hepatology (Baltimore, Md.) (01.09.2023)
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Journal Article
Nicotinamide adenine dinucleotide biosynthesis promotes liver regeneration
Mukherjee, Sarmistha, Chellappa, Karthikeyani, Moffitt, Andrea, Ndungu, Joan, Dellinger, Ryan W., Davis, James G., Agarwal, Beamon, Baur, Joseph A.
Published in Hepatology (Baltimore, Md.) (01.02.2017)
Published in Hepatology (Baltimore, Md.) (01.02.2017)
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Journal Article
Oxidative stress and antioxidants in the pathophysiology of malignant melanoma
Obrador, Elena, Liu-Smith, Feng, Dellinger, Ryan W., Salvador, Rosario, Meyskens, Frank L., Estrela, José M.
Published in Biological chemistry (24.04.2019)
Published in Biological chemistry (24.04.2019)
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Journal Article
Polyphenolic Phytochemicals in Cancer Prevention and Therapy: Bioavailability versus Bioefficacy
Estrela, José M., Mena, Salvador, Obrador, Elena, Benlloch, María, Castellano, Gloria, Salvador, Rosario, Dellinger, Ryan W.
Published in Journal of medicinal chemistry (14.12.2017)
Published in Journal of medicinal chemistry (14.12.2017)
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Journal Article
Gene expression profiles in sporadic ALS fibroblasts define disease subtypes and the metabolic effects of the investigational drug EH301
Fels, Jasmine A, Casalena, Gabriella, Konrad, Csaba, Holmes, Holly E, Dellinger, Ryan W, Manfredi, Giovanni
Published in Human molecular genetics (10.10.2022)
Published in Human molecular genetics (10.10.2022)
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Journal Article
Updates of reactive oxygen species in melanoma etiology and progression
Liu-Smith, Feng, Dellinger, Ryan, Meyskens, Frank L.
Published in Archives of biochemistry and biophysics (01.12.2014)
Published in Archives of biochemistry and biophysics (01.12.2014)
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Journal Article
Pterostilbene in Cancer Therapy
Obrador, Elena, Salvador-Palmer, Rosario, Jihad-Jebbar, Ali, López-Blanch, Rafael, Dellinger, Thanh H, Dellinger, Ryan W, Estrela, José M
Published in Antioxidants (21.03.2021)
Published in Antioxidants (21.03.2021)
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Journal Article
Nicotinamide riboside, pterostilbene and ibudilast protect motor neurons and extend survival in ALS mice
López-Blanch, Rafael, Salvador-Palmer, Rosario, Oriol-Caballo, María, Moreno-Murciano, Paz, Dellinger, Ryan W, Estrela, José M, Obrador, Elena
Published in Neurotherapeutics (01.01.2024)
Published in Neurotherapeutics (01.01.2024)
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Journal Article
Efficacy and tolerability of EH301 for amyotrophic lateral sclerosis: a randomized, double-blind, placebo-controlled human pilot study
de la Rubia, JosÉ E., Drehmer, Eraci, Platero, JosÉ L., Benlloch, MarÍa, Caplliure-Llopis, Jordi, Villaron-Casales, Carlos, de Bernardo, Nieves, AlarcÓn, Jorge, Fuente, Cristian, Carrera, Sandra, Sancho, David, GarcÍa-Pardo, Pilar, Pascual, Raquel, JuÁrez, Marta, Cuerda-Ballester, María, Forner, Alfonso, Sancho-Castillo, Sandra, Barrios, Carlos, Obrador, Elena, Marchio, Patricia, Salvador, Rosario, Holmes, Holly E., Dellinger, Ryan W., Guarente, Leonard, Estrela, José M.
Published in Amyotrophic lateral sclerosis and frontotemporal degeneration (02.01.2019)
Published in Amyotrophic lateral sclerosis and frontotemporal degeneration (02.01.2019)
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Journal Article
Elevated homocysteine is associated with increased rates of epigenetic aging in a population with mild cognitive impairment
Holmes, Holly E, Valentin, Rafael E, Jernerén, Fredrik, de Jager Loots, Celeste A, Refsum, Helga, Smith, A David, Guarente, Leonard, Dellinger, Ryan W, Sampson, Dayle
Published in Aging cell (27.06.2024)
Published in Aging cell (27.06.2024)
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Journal Article
Inhibition of UVB radiation‐induced tissue swelling and immune suppression by nicotinamide riboside and pterostilbene
Isak, Verena, Azizi, Shayan, Zhou, Xi K., Mehta, Devina, Ding, Wanhong, Bulmer, Zakir, Aivazi, Daniella S., Dellinger, Ryan W., Granstein, Richard D.
Published in Photodermatology, photoimmunology & photomedicine (01.05.2024)
Published in Photodermatology, photoimmunology & photomedicine (01.05.2024)
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Journal Article
Safety Assessment of High-Purity, Synthetic Nicotinamide Riboside (NR-E) in a 90-Day Repeated Dose Oral Toxicity Study, With a 28-Day Recovery Arm
Marinescu, Anca G, Chen, Jayson, Holmes, Holly E, Guarente, Leonard, Mendes, Odete, Morris, Mark, Dellinger, Ryan W
Published in International journal of toxicology (01.07.2020)
Published in International journal of toxicology (01.07.2020)
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Journal Article
Anti-cancer drugs elicit re-expression of UDP-glucuronosyltransferases in melanoma cells
Dellinger, Ryan W, Matundan, Harry H, Ahmed, Amelia S, Duong, Priscilla H, Meyskens, Jr, Frank L
Published in PloS one (22.10.2012)
Published in PloS one (22.10.2012)
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Journal Article
12-Hydroxyeicosatetraenoic acid levels are increased in actinic keratoses and squamous cell carcinoma
Laquer, Vivian, Dellinger, Ryan W., Mannering, Irene, Garcia, Angela Gomez, Abraham, Vivek, Pavlis, Janelle, Liu-Smith, Feng, De Feraudy, Sebastien, Meyskens, Frank L., Kelly, Kristen M.
Published in Journal of the American Academy of Dermatology (01.12.2018)
Published in Journal of the American Academy of Dermatology (01.12.2018)
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Journal Article
Combination of natural polyphenols with a precursor of NAD+ and a TLR2/6 ligand lipopeptide protects mice against lethal γ radiation
Obrador, Elena, Salvador-Palmer, Rosario, Pellicer, Blanca, López-Blanch, Rafael, Sirerol, J. Antoni, Villaescusa, Juan I., Montoro, Alegría, Dellinger, Ryan W., Estrela, José M.
Published in Journal of advanced research (01.03.2023)
Published in Journal of advanced research (01.03.2023)
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Journal Article
A randomized placebo-controlled trial of nicotinamide riboside and pterostilbene supplementation in experimental muscle injury in elderly individuals
Jensen, Jonas Brorson, Dollerup, Ole L., Møller, Andreas B., Billeskov, Tine B., Dalbram, Emilie, Chubanava, Sabina, Damgaard, Mads V., Dellinger, Ryan W., Trošt, Kajetan, Moritz, Thomas, Ringgaard, Steffen, Møller, Niels, Treebak, Jonas T., Farup, Jean, Jessen, Niels
Published in JCI insight (10.10.2022)
Published in JCI insight (10.10.2022)
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