Proton and alpha radiation-induced mutational profiles in human cells
Delhomme, Tiffany M., Munteanu, Maia, Buonanno, Manuela, Grilj, Veljko, Biayna, Josep, Supek, Fran
Published in Scientific reports (16.06.2023)
Published in Scientific reports (16.06.2023)
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Multiomic analysis of malignant pleural mesothelioma identifies molecular axes and specialized tumor profiles driving intertumor heterogeneity
Mangiante, Lise, Alcala, Nicolas, Sexton-Oates, Alexandra, Di Genova, Alex, Gonzalez-Perez, Abel, Khandekar, Azhar, Bergstrom, Erik N., Kim, Jaehee, Liu, Xiran, Blazquez-Encinas, Ricardo, Giacobi, Colin, Le Stang, Nolwenn, Boyault, Sandrine, Cuenin, Cyrille, Tabone-Eglinger, Severine, Damiola, Francesca, Voegele, Catherine, Ardin, Maude, Michallet, Marie-Cecile, Soudade, Lorraine, Delhomme, Tiffany M., Poret, Arnaud, Brevet, Marie, Copin, Marie-Christine, Giusiano-Courcambeck, Sophie, Damotte, Diane, Girard, Cecile, Hofman, Veronique, Hofman, Paul, Mouroux, Jérôme, Cohen, Charlotte, Lacomme, Stephanie, Mazieres, Julien, de Montpreville, Vincent Thomas, Perrin, Corinne, Planchard, Gaetane, Rousseau, Nathalie, Rouquette, Isabelle, Sagan, Christine, Scherpereel, Arnaud, Thivolet, Francoise, Vignaud, Jean-Michel, Jean, Didier, Ilg, Anabelle Gilg Soit, Olaso, Robert, Meyer, Vincent, Boland-Auge, Anne, Deleuze, Jean-Francois, Altmuller, Janine, Nuernberg, Peter, Ibáñez-Costa, Alejandro, Castaño, Justo P., Lantuejoul, Sylvie, Ghantous, Akram, Maussion, Charles, Courtiol, Pierre, Hernandez-Vargas, Hector, Caux, Christophe, Girard, Nicolas, Lopez-Bigas, Nuria, Alexandrov, Ludmil B., Galateau-Salle, Françoise, Foll, Matthieu, Fernandez-Cuesta, Lynnette
Published in Nature genetics (01.04.2023)
Published in Nature genetics (01.04.2023)
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Identification of Circulating Tumor DNA for the Early Detection of Small-cell Lung Cancer
Fernandez-Cuesta, Lynnette, Perdomo, Sandra, Avogbe, Patrice H., Leblay, Noemie, Delhomme, Tiffany M., Gaborieau, Valerie, Abedi-Ardekani, Behnoush, Chanudet, Estelle, Olivier, Magali, Zaridze, David, Mukeria, Anush, Vilensky, Marta, Holcatova, Ivana, Polesel, Jerry, Simonato, Lorenzo, Canova, Cristina, Lagiou, Pagona, Brambilla, Christian, Brambilla, Elisabeth, Byrnes, Graham, Scelo, Ghislaine, Le Calvez-Kelm, Florence, Foll, Matthieu, McKay, James D., Brennan, Paul
Published in EBioMedicine (01.08.2016)
Published in EBioMedicine (01.08.2016)
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Clinical evaluation of a low-coverage whole-genome test for detecting homologous recombination deficiency in ovarian cancer
Boidot, Romain, Blum, Michael G.B., Wissler, Marie-Pierre, Gottin, Céline, Ruzicka, Jiri, Chevrier, Sandy, Delhomme, Tiffany M., Audoux, Jérome, Jeanniard, Adrien, Just, Pierre-Alexandre, Harter, Philipp, Pignata, Sandro, González-Martin, Antonio, Marth, Christian, Mäenpää, Johanna, Colombo, Nicoletta, Vergote, Ignace, Fujiwara, Keiichi, Duforet-Frebourg, Nicolas, Bertrand, Denis, Philippe, Nicolas, Ray-Coquard, Isabelle, Pujade-Lauraine, Eric
Published in European journal of cancer (1990) (01.05.2024)
Published in European journal of cancer (1990) (01.05.2024)
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Circulating tumour-derived KRAS mutations in pancreatic cancer cases are predominantly carried by very short fragments of cell-free DNA
Zvereva, Maria, Roberti, Gabriel, Durand, Geoffroy, Voegele, Catherine, Nguyen, Minh Dao, Delhomme, Tiffany M., Chopard, Priscilia, Fabianova, Eleonora, Adamcakova, Zora, Holcatova, Ivana, Foretova, Lenka, Janout, Vladimir, Brennan, Paul, Foll, Matthieu, Byrnes, Graham B., McKay, James D., Scelo, Ghislaine, Le Calvez-Kelm, Florence
Published in EBioMedicine (01.05.2020)
Published in EBioMedicine (01.05.2020)
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The PI3K/mTOR Pathway Is Targeted by Rare Germline Variants in Patients with Both Melanoma and Renal Cell Carcinoma
Hubert, Jean-Noël, Suybeng, Voreak, Vallée, Maxime, Delhomme, Tiffany M, Maubec, Eve, Boland, Anne, Bacq, Delphine, Deleuze, Jean-François, Jouenne, Fanélie, Brennan, Paul, McKay, James D, Avril, Marie-Françoise, Bressac-de Paillerets, Brigitte, Chanudet, Estelle
Published in Cancers (07.05.2021)
Published in Cancers (07.05.2021)
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TP53 Targeted Deep Sequencing of Cell-Free DNA in Esophageal Squamous Cell Carcinoma Using Low-Quality Serum: Concordance with Tumor Mutation
Nasrollahzadeh, Dariush, Roshandel, Gholamreza, Delhomme, Tiffany Myriam, Avogbe, Patrice Hodonou, Foll, Matthieu, Saidi, Farrokh, Poustchi, Hossein, Sotoudeh, Masoud, Malekzadeh, Reza, Brennan, Paul, Mckay, James, Hainaut, Pierre, Abedi-Ardekani, Behnoush
Published in International journal of molecular sciences (26.05.2021)
Published in International journal of molecular sciences (26.05.2021)
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KRAS mutations in blood circulating cell-free DNA: a pancreatic cancer case-control
Le Calvez-Kelm, Florence, Foll, Matthieu, Wozniak, Magdalena B, Delhomme, Tiffany M, Durand, Geoffroy, Chopard, Priscilia, Pertesi, Maroulio, Fabianova, Eleonora, Adamcakova, Zora, Holcatova, Ivana, Foretova, Lenka, Janout, Vladimir, Vallee, Maxime P, Rinaldi, Sabina, Brennan, Paul, McKay, James D, Byrnes, Graham B, Scelo, Ghislaine
Published in Oncotarget (29.11.2016)
Published in Oncotarget (29.11.2016)
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Needlestack: an ultra-sensitive variant caller for multi-sample next generation sequencing data
Delhomme, Tiffany M, Avogbe, Patrice H, Gabriel, Aurélie A G, Alcala, Nicolas, Leblay, Noemie, Voegele, Catherine, Vallée, Maxime, Chopard, Priscilia, Chabrier, Amélie, Abedi-Ardekani, Behnoush, Gaborieau, Valérie, Holcatova, Ivana, Janout, Vladimir, Foretová, Lenka, Milosavljevic, Sasa, Zaridze, David, Mukeriya, Anush, Brambilla, Elisabeth, Brennan, Paul, Scelo, Ghislaine, Fernandez-Cuesta, Lynnette, Byrnes, Graham, Calvez-Kelm, Florence L, McKay, James D, Foll, Matthieu
Published in NAR genomics and bioinformatics (01.06.2020)
Published in NAR genomics and bioinformatics (01.06.2020)
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Urinary TERT promoter mutations are detectable up to 10 years prior to clinical diagnosis of bladder cancer: Evidence from the Golestan Cohort Study
Hosen, Md Ismail, Sheikh, Mahdi, Zvereva, Maria, Scelo, Ghislaine, Forey, Nathalie, Durand, Geoffroy, Voegele, Catherine, Poustchi, Hossein, Khoshnia, Masoud, Roshandel, Gholamreza, Sotoudeh, Masoud, Nikmanesh, Arash, Etemadi, Arash, Avogbe, Patrice Hodonou, Chopard, Priscilia, Delhomme, Tiffany Myriam, Foll, Matthieu, Manel, Arnaud, Vian, Emmanuel, Weiderpass, Elisabete, Kamangar, Farin, Boffetta, Paolo, Pharaoh, Paul D., Dawsey, Sanford M., Abnet, Christian C., Brennan, Paul, McKay, James, Malekzadeh, Reza, Calvez-Kelm, Florence Le
Published in EBioMedicine (01.03.2020)
Published in EBioMedicine (01.03.2020)
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Urinary TERT promoter mutations as non-invasive biomarkers for the comprehensive detection of urothelial cancer
Avogbe, Patrice Hodonou, Manel, Arnaud, Vian, Emmanuel, Durand, Geoffroy, Forey, Nathalie, Voegele, Catherine, Zvereva, Maria, Hosen, Md Ismail, Meziani, Sonia, De Tilly, Berengere, Polo, Gilles, Lole, Olesia, Francois, Pauline, Delhomme, Tiffany Myriam, Carreira, Christine, Monteiro-Reis, Sara, Henrique, Rui, Abedi-Ardekani, Behnoush, Byrnes, Graham, Foll, Matthieu, Weiderpass, Elisabete, McKay, James, Jeronimo, Carmen, Scelo, Ghislaine, Le Calvez-Kelm, Florence
Published in EBioMedicine (01.06.2019)
Published in EBioMedicine (01.06.2019)
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Integrative genomic profiling of large-cell neuroendocrine carcinomas reveals distinct subtypes of high-grade neuroendocrine lung tumors
George, Julie, Walter, Vonn, Peifer, Martin, Alexandrov, Ludmil B., Seidel, Danila, Leenders, Frauke, Maas, Lukas, Müller, Christian, Dahmen, Ilona, Delhomme, Tiffany M., Ardin, Maude, Leblay, Noemie, Byrnes, Graham, Sun, Ruping, De Reynies, Aurélien, McLeer-Florin, Anne, Bosco, Graziella, Malchers, Florian, Menon, Roopika, Altmüller, Janine, Becker, Christian, Nürnberg, Peter, Achter, Viktor, Lang, Ulrich, Schneider, Peter M., Bogus, Magdalena, Soloway, Matthew G., Wilkerson, Matthew D., Cun, Yupeng, McKay, James D., Moro-Sibilot, Denis, Brambilla, Christian G., Lantuejoul, Sylvie, Lemaitre, Nicolas, Soltermann, Alex, Weder, Walter, Tischler, Verena, Brustugun, Odd Terje, Lund-Iversen, Marius, Helland, Åslaug, Solberg, Steinar, Ansén, Sascha, Wright, Gavin, Solomon, Benjamin, Roz, Luca, Pastorino, Ugo, Petersen, Iver, Clement, Joachim H., Sänger, Jörg, Wolf, Jürgen, Vingron, Martin, Zander, Thomas, Perner, Sven, Travis, William D., Haas, Stefan A., Olivier, Magali, Foll, Matthieu, Büttner, Reinhard, Hayes, David Neil, Brambilla, Elisabeth, Fernandez-Cuesta, Lynnette, Thomas, Roman K.
Published in Nature communications (13.03.2018)
Published in Nature communications (13.03.2018)
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Development of Sensitive Droplet Digital PCR Assays for Detecting Urinary TERT Promoter Mutations as Non-Invasive Biomarkers for Detection of Urothelial Cancer
Hosen, Md Ismail, Forey, Nathalie, Durand, Geoffroy, Voegele, Catherine, Bilici, Selin, Avogbe, Patrice Hodonou, Delhomme, Tiffany Myriam, Foll, Matthieu, Manel, Arnaud, Vian, Emmanuel, Meziani, Sonia, De Tilly, Berengere, Polo, Gilles, Lole, Olesia, Francois, Pauline, Boureille, Antoine, Pisarev, Eduard, Salas, Andrei R O S E, Monteiro-Reis, Sara, Henrique, Rui, Byrnes, Graham, Jeronimo, Carmen, Scelo, Ghislaine, McKay, James D, Calvez-Kelm, Florence Le, Zvereva, Maria
Published in Cancers (27.11.2020)
Published in Cancers (27.11.2020)
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Disentangling heterogeneity of Malignant Pleural Mesothelioma through deep integrative omics analyses
Mangiante, Lise, Alcala, Nicolas, Alex Di Genova, Sexton-Oates, Alexandra, Gonzalez-Perez, Abel, Khandekar, Azhar, Bergstrom, Erik, Kim, Jaehee, Giacobi, Colin, Le-Stang, Nolwenn, Boyault, Sandrine, Cuenin, Cyrille, Tabone-Eglinger, Severine, Damiola, Francesca, Voegele, Catherine, Ardin, Maude, Marie-Cecile Michallet, Soudade, Lorraine, Delhomme, Tiffany, Poret, Arnaud, Brevet, Marie, Marie-Christine Copin, Giusiano-Courcambeck, Sophie, Damotte, Diane, Girard, Cecile, Hofman, Veronique, Hofman, Paul, Mouroux, Jerome, Lacomme, Stephanie, Mazieres, Julien, De Montpreville, Vincent Thomas, Perrin, Corinne, Planchard, Gaetane, Rouquette, Isabelle, Sagan, Christine, Scherpereel, Arnaud, Thivolet, Francoise, Jean-Michel Vignaud, Dider Jean, Anabelle Gilg Soit Ilg, Olaso, Robert, Meyer, Vincent, Boland, Anne, Deleuze, Jean-Francois, Altmuller, Janine, Nuernberg, Peter, Lantuejoul, Sylvie, Ghantous, Akram, Maussion, Charles, Courtiol, Pierre, Hernandez-Vargas, Hector, Caux, Christophe, Girard, Nicolas, Lopez-Bigas, Nuria, Alexandrov, Ludmil, Francoise Galateau Salle, Foll, Matthieu, Fernandez-Cuesta, Lynnette
Published in bioRxiv (29.09.2021)
Published in bioRxiv (29.09.2021)
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Abstract 5358: Multi-omics comparative analyses of pulmonary typical carcinoids, atypical carcinoids, and large-cell neuroendocrine carcinoma
Leblay, Noémie, Alcala, Nicolas, Marin, David Hervás, Delhomme, Tiffany M., Giffon, Théo, Ghantous, Akram, Chabrier, Amélie, Cuenin, Cyrille, Altmueller, Janine, Durand, Geoffroy, Voegele, Catherine, Lorimier, Philippe, Toffart, Anne-Claire, Derks, Jules, Brustugun, Odd Terje, Clement, Joachim H., Saenger, Joerg, Field, John K., Soltermann, Alex, Wright, Gavin M., Roz, Luca, Muscarella, Lucia Anna, Graziano, Paolo, Herceg, Zdenko, Speel, Ernst-Jan, Nuernberg, Peter, McKay, James, Girard, Nicolas, Lantuejoul, Sylvie, Sandoval, Juan, Brambilla, Elisabeth, Foll, Matthieu, Fernandez-Cuesta, Lynnette
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Abstract 3137: NGS-based detection of KRAS hotspot mutations in plasma cell-free DNA of pancreatic cancer cases
Le Calvez-Kelm, Florence, Foll, Matthieu, Wozniak, Magdalena B., Durand, Geoffroy, Chopard, Priscilia, Pertesi, Maroulio, Delhomme, Tiffany, Holcatova, Ivana, Foretova, Lenka, Janout, Vladimir, Fabianova, Eleonora, Vallée, Maxime P., Brennan, Paul, McKay, James D., Byrnes, Graham, Scélo, Ghislaine
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Abstract 3156: NGS-based screening for TP53 mutations in circulating cell-free DNA: A first step towards early detection of lung cancers
Avogbe, Patrice H., Delhomme, Tiffany, Leblay, Noémie, Le Calvez-Kelm, Florence, Chopard, Priscilia, Gaborieau, Valérie, Scelo, Ghislaine, Abedi-Ardekani, Behnoush, Zaridze, David, Mukeria, Anush, Byrnes, Graham, Brennan, Paul, Fernandez-Cuesta, Lynnette, Foll, Matthieu, McKay, James D.
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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MA11.05 A Case-Control Study to Test the Use of ctDNA in the Early Detection of SCLC Reveals TP53 Mutations in Non-Cancer Controls
Fernandez-Cuesta, Lynnette, Perdomo, Sandra, Avogbe, Patrice, Leblay, Noémie, Delhomme, Tiffany, Gaborieau, Valerie, Abedi-Ardekani, Behnoush, Chanudet, Estelle, Olivier, Magali, Zaridze, David, Mukeria, Anush, Vilensky, Marta, Holcatova, Ivana, Polesel, Jerry, Simonato, Lorenzo, Canova, Cristina, Lagiou, Pagona, Brambilla, Christian, Brambilla, Elisabeth, Byrnes, Graham, Scelo, Ghislaine, Le Calvez-Kelm, Florence, Foll, Matthieu, Mckay, James, Brennan, Paul
Published in Journal of thoracic oncology (01.01.2017)
Published in Journal of thoracic oncology (01.01.2017)
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Urinary TERT promoter mutations as non-invasive biomarkers for the comprehensive detection of urothelial cancerResearch in context
Patrice Hodonou Avogbe, Arnaud Manel, Emmanuel Vian, Geoffroy Durand, Nathalie Forey, Catherine Voegele, Maria Zvereva, Md Ismail Hosen, Sonia Meziani, Berengere De Tilly, Gilles Polo, Olesia Lole, Pauline Francois, Tiffany Myriam Delhomme, Christine Carreira, Sara Monteiro-Reis, Rui Henrique, Behnoush Abedi-Ardekani, Graham Byrnes, Matthieu Foll, Elisabete Weiderpass, James McKay, Carmen Jeronimo, Ghislaine Scelo, Florence Le Calvez-Kelm
Published in EBioMedicine (01.06.2019)
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Published in EBioMedicine (01.06.2019)
Journal Article
Needlestack: an ultra-sensitive variant caller for multi-sample next generation sequencing data
Delhomme, Tiffany M, Avogbe, Patrice H, Gabriel, Aurelie Ag, Alcala, Nicolas, Leblay, Noemie, Voegele, Catherine, Vallee, Maxime, Chopard, Priscilia, Chabrier, Amelie, Abedi-Ardekani, Behnoush, Gaborieau, Valerie, Holcatova, Ivana, Janout, Vladimir, etova, Lenka, Milosavljevic, Sasa, Zaridze, David, Mukeriya, Anush, Brambilla, Elisabeth, Brennan, Paul, Scelo, Ghislaine, Fernandez-Cuesta, Lynnette, Byrnes, Graham, Florence Le Calvez-Kelm, Mckay, James D D, Foll, Matthieu
Published in bioRxiv (21.05.2019)
Published in bioRxiv (21.05.2019)
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