Efficacy and Safety of Pimodivir Combined with Standard-of-care in Hospitalized and Non-hospitalized High-risk Adolescents and Adults with Influenza A Infection
Leopold, Lorant, Vingerhoets, Johan, Deleu, Sofie, Nalpas, Catherine, Weber, Karin, van Dromme, Ilse, Lowson, David, Michiels, Bart, van Duijnhoven, Wilbert
Published in The Journal of infectious diseases (22.08.2024)
Published in The Journal of infectious diseases (22.08.2024)
Get full text
Journal Article
A Phase 2 Study of Pimodivir (JNJ-63623872) in Combination With Oseltamivir in Elderly and Nonelderly Adults Hospitalized With Influenza A Infection: OPAL Study
O’Neil, Brian, Ison, Michael G, Hallouin-Bernard, Marie Charlotte, Nilsson, Anna C, Torres, Antoni, Wilburn, John M, van Duijnhoven, Wilbert, Van Dromme, Ilse, Anderson, David, Deleu, Sofie, Kosoglou, Teddy, Vingerhoets, Johan, Rossenu, Stefaan, Leopold, Lorant
Published in The Journal of infectious diseases (12.08.2022)
Published in The Journal of infectious diseases (12.08.2022)
Get full text
Journal Article
CROCuS, a Phase II Study Evaluating the Antiviral Activity, Clinical Outcomes, and Safety of Rilematovir in Children Aged ≥ 28 Days and ≤ 3 Years with Acute Respiratory Tract Infection Due to Respiratory Syncytial Virus
Ferrero, Fernando, Lin, Chien-Yu, Liese, Johannes, Luz, Kleber, Stoeva, Tatyana, Nemeth, Agnes, Gijón, Manuel, Calvo, Cristina, Natalini, Silvina, Toh, Teck-Hock, Deleu, Sofie, Chen, Bohang, Rusch, Sarah, Sánchez, Beatriz López, Leipoldt, Illse, Vijgen, Leen, Huntjens, Dymphy, Baguet, Tristan, Bertzos, Kristi, Gamil, Mohamed, Stevens, Marita
Published in Paediatric drugs (01.07.2024)
Published in Paediatric drugs (01.07.2024)
Get full text
Journal Article
Single‐ and multiple‐dose pharmacokinetics and safety of pimodivir, a novel, non‐nucleoside polymerase basic protein 2 subunit inhibitor of the influenza A virus polymerase complex, and interaction with oseltamivir: a Phase 1 open‐label study in healthy volunteers
Deleu, Sofie, Kakuda, Thomas N., Spittaels, Kurt, Vercauteren, Jurgen J., Hillewaert, Vera, Lwin, Amy, Leopold, Lorant, Hoetelmans, Richard M. W.
Published in British journal of clinical pharmacology (01.11.2018)
Published in British journal of clinical pharmacology (01.11.2018)
Get full text
Journal Article
Absence of QTc prolongation with domperidone: A randomized, double-blind, placebo- and positive-controlled thorough QT/QTc study in healthy volunteers
Biewenga, Jeike, Keung, Chi, Solanki, Bhavna, Natarajan, Jaya, Leitz, Gerhard, Deleu, Sofie, Soons, Paul
Published in Clinical pharmacology in drug development (01.01.2015)
Published in Clinical pharmacology in drug development (01.01.2015)
Get full text
Journal Article