Immune checkpoint inhibition in sepsis: a Phase 1b randomized study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of nivolumab
Hotchkiss, Richard S., Colston, Elizabeth, Yende, Sachin, Crouser, Elliott D., Martin, Greg S., Albertson, Timothy, Bartz, Raquel R., Brakenridge, Scott C., Delano, Matthew J., Park, Pauline K., Donnino, Michael W., Tidswell, Mark, Mayr, Florian B., Angus, Derek C., Coopersmith, Craig M., Moldawer, Lyle L., Catlett, Ian M., Girgis, Ihab G., Ye, June, Grasela, Dennis M.
Published in Intensive care medicine (01.10.2019)
Published in Intensive care medicine (01.10.2019)
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Diabetes and Sepsis: Risk, Recurrence, and Ruination
Frydrych, Lynn M, Fattahi, Fatemeh, He, Katherine, Ward, Peter A, Delano, Matthew J
Published in Frontiers in endocrinology (Lausanne) (30.10.2017)
Published in Frontiers in endocrinology (Lausanne) (30.10.2017)
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B cells enhance early innate immune responses during bacterial sepsis
Kelly-Scumpia, Kindra M, Scumpia, Philip O, Weinstein, Jason S, Delano, Matthew J, Cuenca, Alex G, Nacionales, Dina C, Wynn, James L, Lee, Pui Y, Kumagai, Yutaro, Efron, Philip A, Akira, Shizuo, Wasserfall, Clive, Atkinson, Mark A, Moldawer, Lyle L
Published in The Journal of experimental medicine (01.08.2011)
Published in The Journal of experimental medicine (01.08.2011)
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Complications and resource utilization in trauma patients with diabetes
He, Katherine, Hemmila, Mark R, Cain-Nielsen, Anne H, Machado-Aranda, David A, Frydrych, Lynn M, Delano, Matthew J
Published in PloS one (28.08.2019)
Published in PloS one (28.08.2019)
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Defective innate immunity predisposes murine neonates to poor sepsis outcome but is reversed by TLR agonists
Wynn, James L., Scumpia, Philip O., Winfield, Robert D., Delano, Matthew J., Kelly-Scumpia, Kindra, Barker, Tolga, Ungaro, Ricardo, Levy, Ofer, Moldawer, Lyle L.
Published in Blood (01.09.2008)
Published in Blood (01.09.2008)
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Incidence, clinical predictors, genomics, and outcome of acute kidney injury among trauma patients
Bihorac, Azra, Delano, Matthew J, Schold, Jesse D, Lopez, Maria Cecilia, Nathens, Avery B, Maier, Ronald V, Layon, Abraham Joseph, Baker, Henry V, Moldawer, Lyle L
Published in Annals of surgery (01.07.2010)
Published in Annals of surgery (01.07.2010)
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Journal Article
Type I interferon signaling in hematopoietic cells is required for survival in mouse polymicrobial sepsis by regulating CXCL10
Kelly-Scumpia, Kindra M, Scumpia, Philip O, Delano, Matthew J, Weinstein, Jason S, Cuenca, Alex G, Wynn, James L, Moldawer, Lyle L
Published in The Journal of experimental medicine (15.02.2010)
Published in The Journal of experimental medicine (15.02.2010)
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Neutrophil mobilization from the bone marrow during polymicrobial sepsis is dependent on CXCL12 signaling
Delano, Matthew J, Kelly-Scumpia, Kindra M, Thayer, Terri C, Winfield, Robert D, Scumpia, Philip O, Cuenca, Alex G, Harrington, Phillips B, O'Malley, Kerri A, Warner, Elizabeth, Gabrilovich, Sonia, Mathews, Clayton E, Laface, Drake, Heyworth, Paul G, Ramphal, Reuben, Strieter, Robert M, Moldawer, Lyle L, Efron, Philip A
Published in The Journal of immunology (1950) (15.07.2011)
Published in The Journal of immunology (1950) (15.07.2011)
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Disruption of Neutrophil Extracellular Traps (NETs) Links Mechanical Strain to Post-traumatic Inflammation
Agarwal, Shailesh, Loder, Shawn J, Cholok, David, Li, John, Bian, Guowu, Yalavarthi, Srilakshmi, Li, Shuli, Carson, William F, Hwang, Charles, Marini, Simone, Pagani, Chase, Edwards, Nicole, Delano, Matthew J, Standiford, Theodore J, Knight, Jason S, Kunkel, Steven L, Mishina, Yuji, Ward, Peter A, Levi, Benjamin
Published in Frontiers in immunology (24.10.2019)
Published in Frontiers in immunology (24.10.2019)
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Journal Article
Cutting Edge: Bacterial Infection Induces Hematopoietic Stem and Progenitor Cell Expansion in the Absence of TLR Signaling
Scumpia, Philip O, Kelly-Scumpia, Kindra M, Delano, Matthew J, Weinstein, Jason S, Cuenca, Alex G, Al-Quran, Samer, Bovio, Ian, Akira, Shizuo, Kumagai, Yutaro, Moldawer, Lyle L
Published in The Journal of immunology (1950) (01.03.2010)
Published in The Journal of immunology (1950) (01.03.2010)
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Journal Article
Novel role for tumor-induced expansion of myeloid-derived cells in cancer cachexia
Cuenca, Alex G, Cuenca, Angela L, Winfield, Robert D, Joiner, Dallas N, Gentile, Lori, Delano, Matthew J, Kelly-Scumpia, Kindra M, Scumpia, Philip O, Matheny, Michael K, Scarpace, Philip J, Vila, Lizette, Efron, Philip A, LaFace, Drake M, Moldawer, Lyle L
Published in The Journal of immunology (1950) (15.06.2014)
Published in The Journal of immunology (1950) (15.06.2014)
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A road map from single-cell transcriptome to patient classification for the immune response to trauma
Chen, Tianmeng, Delano, Matthew J, Chen, Kong, Sperry, Jason L, Namas, Rami A, Lamparello, Ashley J, Deng, Meihong, Conroy, Julia, Moldawer, Lyle L, Efron, Philip A, Loughran, Patricia, Seymour, Christopher, Angus, Derek C, Vodovotz, Yoram, Chen, Wei, Billiar, Timothy R
Published in JCI insight (25.01.2021)
Published in JCI insight (25.01.2021)
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Comorbid status in patients with osteomyelitis is associated with long-term incidence of extremity amputation
Schmidt, Brian M, Keeney-Bonthrone, Toby P, Hawes, Armani M, Karmakar, Monika, Frydrych, Lynn M, Cinti, Sandro K, Pop-Busui, Rodica, Delano, Matthew J
Published in BMJ open diabetes research & care (12.12.2023)
Published in BMJ open diabetes research & care (12.12.2023)
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Journal Article
Increased mortality and altered immunity in neonatal sepsis produced by generalized peritonitis
Wynn, James L, Scumpia, Philip O, Delano, Matthew J, O'Malley, Kerri A, Ungaro, Ricardo, Abouhamze, Amer, Moldawer, Lyle L
Published in Shock (Augusta, Ga.) (01.12.2007)
Published in Shock (Augusta, Ga.) (01.12.2007)
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Critical Role for CXC Ligand 10/CXC Receptor 3 Signaling in the Murine Neonatal Response to Sepsis
Cuenca, Alex G, Wynn, James L, Kelly-Scumpia, Kindra M, Scumpia, Philip O, Vila, Lizette, Delano, Matthew J, Mathews, Clayton E, Wallet, Shannon M, Reeves, Westley H, Behrns, Kevin E, Nacionales, Dina C, Efron, Philip A, Kunkel, Steven L, Moldawer, Lyle L
Published in Infection and Immunity (01.07.2011)
Published in Infection and Immunity (01.07.2011)
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Journal Article
Cecal ligation and puncture
Cuenca, Alex G, Delano, Matthew J, Kelly-Scumpia, Kindra M, Moldawer, Lyle L, Efron, Philip A
Published in Current protocols in immunology (01.11.2010)
Published in Current protocols in immunology (01.11.2010)
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Trauma-induced heterotopic bone formation and the role of the immune system: A review
Kraft, Casey T, Agarwal, Shailesh, Ranganathan, Kavitha, Wong, Victor W, Loder, Shawn, Li, John, Delano, Matthew J, Levi, Benjamin
Published in The journal of trauma and acute care surgery (01.01.2016)
Published in The journal of trauma and acute care surgery (01.01.2016)
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