6‑Substituted Pyrrolo[2,3‑d]pyrimidine Thienoyl Regioisomers as Targeted Antifolates for Folate Receptor α and the Proton-Coupled Folate Transporter in Human Tumors
Wang, Lei, Wallace, Adrianne, Raghavan, Sudhir, Deis, Siobhan M., Wilson, Mike R., Yang, Si, Polin, Lisa, White, Kathryn, Kushner, Juiwanna, Orr, Steven, George, Christina, O’Connor, Carrie, Hou, Zhanjun, Mitchell-Ryan, Shermaine, Dann, Charles E., Matherly, Larry H., Gangjee, Aleem
Published in Journal of medicinal chemistry (10.09.2015)
Published in Journal of medicinal chemistry (10.09.2015)
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Tumor Targeting with Novel 6‑Substituted Pyrrolo [2,3‑d] Pyrimidine Antifolates with Heteroatom Bridge Substitutions via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis
Golani, Lalit K, Wallace-Povirk, Adrianne, Deis, Siobhan M, Wong, Jennifer, Ke, Jiyuan, Gu, Xin, Raghavan, Sudhir, Wilson, Mike R, Li, Xinxin, Polin, Lisa, de Waal, Parker W, White, Kathryn, Kushner, Juiwanna, O’Connor, Carrie, Hou, Zhanjun, Xu, H. Eric, Melcher, Karsten, Dann, Charles E, Matherly, Larry H, Gangjee, Aleem
Published in Journal of medicinal chemistry (08.09.2016)
Published in Journal of medicinal chemistry (08.09.2016)
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Correction to Structural and Enzymatic Analysis of Tumor-Targeted Antifolates That Inhibit Glycinamide Ribonucleotide Formyltransferase
Deis, Siobhan M, Doshi, Arpit, Hou, Zhanjun, Matherly, Larry H, Gangjee, Aleem, Dann, Charles E
Published in Biochemistry (Easton) (21.02.2017)
Published in Biochemistry (Easton) (21.02.2017)
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Structural and Enzymatic Analysis of Tumor-Targeted Antifolates That Inhibit Glycinamide Ribonucleotide Formyltransferase
Deis, Siobhan M, Doshi ArpitauthorDivision of Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Duquesne University, 600 Forbes Avenue, Pittsburgh, Pennsylvania 15282, United States, Hou ZhanjunauthorMolecular Therapeutics Program, Barbara Ann Karmanos Cancer Institute, 110 East Warren Avenue, Detroit, Michigan 48201, United StatesDepartment of Oncology, Wayne State University School of Medicine, Detroit, Michigan 48201, United States, Matherly Larry H.authorMolecular Therapeutics Program, Barbara Ann Karmanos Cancer Institute, 110 East Warren Avenue, Detroit, Michigan 48201, United StatesDepartment of Oncology, Wayne State University School of Medicine, Detroit, Michigan 48201, United StatesDepartment of Pharmacology, Wayne State University School of Medicine, Detroit, Michigan 48201, United States, Gangjee AleemauthorDivision of Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Duquesne University, 600 Forbes Avenue, Pittsburgh, Pennsylvania 15282, United States, Dann Charles E.author
Year of Publication 2015
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Year of Publication 2015
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