ACYCLIC/CARBOCYCLIC GUANOSINE ANALOGUES AS ANTI-HERPESVIRUS AGENTS
De Clercq, E., Andrei, G., Snoeck, R., De Bolle, L., Naesens, L., Degrève, B., Balzarini, J., Zhang, Y., Schols, D., Leyssen, P., Ying, C., Neyts, J.
Published in Nucleosides, nucleotides & nucleic acids (01.01.2001)
Published in Nucleosides, nucleotides & nucleic acids (01.01.2001)
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Potent antitumor activity of the acyclic nucleoside phosphonate 9‐(2‐phosphonylmethoxyethyl)adenine in choriocarcinoma‐bearing rats
Hatse, S., Naesens, L., Degrève, B., Segers, C., Vandeputte, M., Waer, M., De Clercq, E., Balzarini, J.
Published in International journal of cancer (18.05.1998)
Published in International journal of cancer (18.05.1998)
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Varicella-zoster virus thymidine kinase gene and antiherpetic pyrimidine nucleoside analogues in a combined gene/chemotherapy treatment for cancer
DEGREVE, B, ANDREI, G, BALZARINI, J, IZQUIERDO, M, PIETTE, J, MORIN, K, KNAUS, E. E, WIEBE, L. I, BASRAH, I, WALKERS, R. T, DE CLERCQ, E
Published in Gene therapy (01.10.1997)
Published in Gene therapy (01.10.1997)
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Budding Yeast as a Screening Tool for Discovery of Nucleoside Analogs for Use in HSV-1 TK Suicide-Gene Therapy
Wera, S, Degrève, B, Balzarini, J, De Clercq, E, Thevelein, J.M, Neyts, J
Published in BioTechniques (01.10.1999)
Published in BioTechniques (01.10.1999)
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The Multifunctional Deoxynucleoside Kinase of Insect Cells Is a Target for the Development of New Insecticides
Balzarini, J, Degrève, B, Hatse, S, De Clercq, E, Breuer, M, Johansson, M, Huybrechts, R, Karlsson, A
Published in Molecular pharmacology (01.04.2000)
Published in Molecular pharmacology (01.04.2000)
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In vitro and in vivo inhibitory activity of the differentiation-inducing agent 9-(2-phosphonylmethoxyethyl)adenine (PMEA) against rat choriocarcinoma
Hatse, S, Naesens, L, Degrève, B, Vandeputte, M, Waer, M, De Clercq, E, Balzarini, J
Published in Advances in experimental medicine and biology (1998)
Published in Advances in experimental medicine and biology (1998)
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Comparative in vitro and in vivo cytotoxic activity of (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) and its arabinosyl derivative, (E)-5-(2-bromovinyl)-1-beta-D-arabinofuranosyluracil (BVaraU), against tumor cells expressing either the Varicella zoster or the Herpes simplex virus thymidine kinase
Grignet-Debrus, C, Cool, V, Baudson, N, Degrève, B, Balzarini, J, De Leval, L, Debrus, S, Velu, T, Calberg-Bacq, C M
Published in Cancer gene therapy (01.02.2000)
Published in Cancer gene therapy (01.02.2000)
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Kinetic analysis of novel multisubstrate analogue inhibitors of thymidine phosphorylase
Balzarini, Jan, Degrève, Bart, Esteban-Gamboa, Antonio, Esnouf, Robert, De Clercq, Erik, Engelborghs, Yves, Camarasa, Maria-José, Pérez-Pérez, Maria-Jesús
Published in FEBS letters (20.10.2000)
Published in FEBS letters (20.10.2000)
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Differential Intracellular Compartmentalization of Herpetic Thymidine Kinases (TKs) in TK Gene-Transfected Tumor Cells: Molecular Characterization of the Nuclear Localization Signal of Herpes Simplex Virus Type 1 TK
Degrève, B, Johansson, M, De Clercq, E, Karlsson, A, Balzarini, J
Published in Journal of Virology (01.12.1998)
Published in Journal of Virology (01.12.1998)
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Superior cytostatic activity of the ganciclovir elaidic acid ester due to the prolonged intracellular retention of ganciclovir anabolites in herpes simplex virus type 1 thymidine kinase gene-transfected tumor cells
BALZARINI, J, DEGREVE, B, ANDREI, G, NEYTS, J, SANDVOLD, M, MYHREN, F, DE CLERCQ, E
Published in Gene therapy (01.03.1998)
Published in Gene therapy (01.03.1998)
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2′- O-Acyl/alkyl-substituted arabinosyl nucleosides as inhibitors of human mitochondrial thymidine kinase
Balzarinia, Jan, Degrève, Bart, Zhu, Chaoyong, Durini, Elisa, Porcu, Luca, De Clercq, Erik, Karlsson, Anna, Manfredini, Stefano
Published in Biochemical pharmacology (15.03.2001)
Published in Biochemical pharmacology (15.03.2001)
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