Molecular Target Class Is Predictive of In vitro Response Profile
GRESHOCK, Joel, BACHMAN, Kurtis E, HARDWICKE, Mary Ann, WOOSTER, Richard, DEGENHARDT, Yan Y, JUNPING JING, WEN, Yuan H, EASTMAN, Stephen, MCNEIL, Elizabeth, MOY, Christopher, WEGRZYN, Ronald, AUGER, Kurt
Published in Cancer research (Chicago, Ill.) (01.05.2010)
Published in Cancer research (Chicago, Ill.) (01.05.2010)
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Journal Article
Metastatic Properties and Genomic Amplification of the Tyrosine Kinase Gene ACK1
Edward Htun van der Horst, Yan Y. Degenhardt, Strelow, Astrid, Slavin, Anthony, Lawrence Chinn, Jessica Orf, Rong, Minqing, Li, Shyun, Lei-Hoon See, Ken Q. C. Nguyen, Hoey, Timothy, Wesche, Holger, Powers, Scott, McKnight, Steven L.
Published in Proceedings of the National Academy of Sciences - PNAS (01.11.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (01.11.2005)
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Journal Article
Mitogen‐activated protein kinase (MEK/ERK) inhibition sensitizes cancer cells to centromere‐associated protein E inhibition
Mayes, Patrick A., Degenhardt, Yan Y., Wood, Andrew, Toporovskya, Yana, Diskin, Sharon J., Haglund, Elizabeth, Moy, Christopher, Wooster, Richard, Maris, John M.
Published in International journal of cancer (01.02.2013)
Published in International journal of cancer (01.02.2013)
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Assessment of epidermal growth factor receptor (EGFR, ErbB1) and HER2 (ErbB2) protein expression levels and response to lapatinib (Tykerb®, GW572016) in an expanded panel of human normal and tumour cell lines
Rusnak, D. W., Alligood, K. J., Mullin, R. J., Spehar, G. M., Arenas-Elliott, C., Martin, A.-M., Degenhardt, Y., Rudolph, S. K., Jr Haws, T. F., Hudson-Curtis, B. L., Gilmer, T. M.
Published in Cell proliferation (01.08.2007)
Published in Cell proliferation (01.08.2007)
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Pooled shRNA screen for sensitizers to inhibition of the mitotic regulator polo-like kinase (PLK1)
Liu-Sullivan, Nancy, Zhang, Jianping, Bakleh, Amy, Marchica, John, Li, Jinyu, Siolas, Despina, Laquerre, Sylvie, Degenhardt, Yan Y, Wooster, Richard, Chang, Kenneth, Hannon, Gregory F, Powers, Scott
Published in Oncotarget (01.12.2011)
Published in Oncotarget (01.12.2011)
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Journal Article
Phase I Study of GSK461364, a Specific and Competitive Polo-like Kinase 1 Inhibitor, in Patients with Advanced Solid Malignancies
OLMOS, David, BARKER, Douglas, SMITH, Deborah A, MURRAY, Sharon C, LAMPKIN, Thomas A, DAR, Mohammed M, WILSON, Richard, DE BONO, Johann S, BLAGDEN, Sarah P, SHARMA, Rohini, BRUNETTO, Andre T, YAP, Timothy A, TAEGTMEYER, Anne B, BARRIUSO, Jorge, MEDANI, Hanine, DEGENHARDT, Yan Y, ALLRED, Alicia J
Published in Clinical cancer research (15.05.2011)
Published in Clinical cancer research (15.05.2011)
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Critical role for Daxx in regulating Mdm2
Yang, Xiaolu, Tang, Jun, Qu, Li-Ke, Zhang, Jianke, Wang, Wenge, Michaelson, Jennifer S, Degenhardt, Yan Y, El-Deiry, Wafik S
Published in Nature cell biology (01.08.2006)
Published in Nature cell biology (01.08.2006)
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Abstract CT034: A phase I study of GSK2857916, a BCMA-directed monoclonal antibody conjugated to microtubule-disrupting agent in patients with relapsed, refractory multiple myeloma and other BCMA-expressing hematologic malignancies
Anderson, Larry D., Cavet, James, Cohen, Adam D., Degenhardt, Yan Y., Ellis, Catherine E., Germaschewski, Fiona, Lendvai, Nikoletta, Libby, Edward, Opalinska, Joanna, Popat, Rakesh, Pouliquen, Isabelle, Richardson, Paul G., Stockerl-Goldstein, Keith E., Sutherland, Heather J., Trudel, Suzanne, Voorhees, Peter M., Wetherington, Jeffrey
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Inhibition of Polo-like kinase 1 prevents the growth of metastatic breast cancer cells in the brain
Qian, Yongzhen, Hua, Emily, Bisht, Kheem, Woditschka, Stephan, Skordos, Konstantine W., Liewehr, David J., Steinberg, Seth M., Brogi, Edi, Akram, Muzaffar M., Killian, J. Keith, Edelman, Daniel C., Pineda, Marbin, Scurci, Stephanie, Degenhardt, Yan Y., Laquerre, Sylvie, Lampkin, Thomas A., Meltzer, Paul S., Camphausen, Kevin, Steeg, Patricia S., Palmieri, Diane
Published in Clinical & experimental metastasis (01.12.2011)
Published in Clinical & experimental metastasis (01.12.2011)
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Journal Article
99 POSTER Models for response to the MEK inhibitor GSK1120212 confirm RAS and BRAF mutations as predictive biomarkers and suggest other, unexpected tumor types for clinical evaluation
Wooster, R, Cornwell, W, Jing, J, Greshock, J, Gilmartin, A, Sutton, D, Jackson, J, Laquerre, S, Weber, B, Degenhardt, Y
Published in European journal of cancer supplements (2008)
Published in European journal of cancer supplements (2008)
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Journal Article
High-content analysis of cancer genome DNA alterations
Degenhardt, Yan Y, Wooster, Richard, McCombie, Richard W, Lucito, Robert, Powers, Scott
Published in Current opinion in genetics & development (01.02.2008)
Published in Current opinion in genetics & development (01.02.2008)
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Journal Article
Wip1-deficient mice are resistant to common cancer genes
Harrison, Martin, Li, Jing, Degenhardt, Yan, Hoey, Timothy, Powers, Scott
Published in Trends in molecular medicine (01.08.2004)
Published in Trends in molecular medicine (01.08.2004)
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Journal Article
Abstract B173: Synergistic interaction between CENP-E inhibitor GSK923295 and MEK inhibitor GSK1120212
Degenhardt, Yan Y., Zhang, Xiping, Moy, Christopher, Conway, Theresa, Mcneil, Liz, Jing, Junping, Greshock, Joel, Wegrzyn, Ronald, Yin, Holy, Mousses, Spyro, Wooster, Richard, Bachman, Kurtis
Published in Molecular cancer therapeutics (10.12.2009)
Published in Molecular cancer therapeutics (10.12.2009)
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Journal Article
Proteínas de ligação a antígeno
KENNETH WILLIAM HANCE, GUAN JUN, PETER JOSEPH MORLEY, YAN Y. DEGENHARDT
Year of Publication 21.06.2022
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Year of Publication 21.06.2022
Patent
ANTIGEN BINDING PROTEINS AND COMBINATIONS THEREOF
DEGENHARDT, Yan Y, HANCE, Kenneth William, GUAN, Jun, ROTH, Iris, MORLEY, Peter
Year of Publication 23.05.2024
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Year of Publication 23.05.2024
Patent
ANTIGEN BINDING PROTEINS AND COMBINATIONS THEREOF
DEGENHARDT, Yan Y, HANCE, Kenneth William, GUAN, Jun, MORLEY, Peter Joseph, ROTH, Iris
Year of Publication 07.02.2024
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Year of Publication 07.02.2024
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Antigen Binding Proteins
DEGENHARDT, Yan Y, HANCE, Kenneth William, GUAN, Jun, MORLEY, Peter Joseph
Year of Publication 07.09.2023
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Year of Publication 07.09.2023
Patent