Evaluation of variable selection methods for random forests and omics data sets
Degenhardt, Frauke, Seifert, Stephan, Szymczak, Silke
Published in Briefings in bioinformatics (22.03.2019)
Published in Briefings in bioinformatics (22.03.2019)
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Journal Article
Hypothalamic Inflammation in Human Obesity Is Mediated by Environmental and Genetic Factors
Kreutzer, Carina, Peters, Sönke, Schulte, Dominik M, Fangmann, Daniela, Türk, Kathrin, Wolff, Stephan, van Eimeren, Thilo, Ahrens, Markus, Beckmann, Jan, Schafmayer, Clemens, Becker, Thomas, Kerby, Tina, Rohr, Axel, Riedel, Christian, Heinsen, Femke-Anouska, Degenhardt, Frauke, Franke, Andre, Rosenstiel, Philip, Zubek, Nana, Henning, Christian, Freitag-Wolf, Sandra, Dempfle, Astrid, Psilopanagioti, Aristea, Petrou-Papadaki, Helen, Lenk, Lennart, Jansen, Olav, Schreiber, Stefan, Laudes, Matthias
Published in Diabetes (New York, N.Y.) (01.09.2017)
Published in Diabetes (New York, N.Y.) (01.09.2017)
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Journal Article
Atopic dermatitis is associated with an increased risk for rheumatoid arthritis and inflammatory bowel disease, and a decreased risk for type 1 diabetes
Schmitt, Jochen, MD, MPH, Schwarz, Kristin, MSc, Baurecht, Hansjörg, MSc, Hotze, Melanie, MSc, Fölster-Holst, Regina, MD, Rodríguez, Elke, PhD, Lee, Young A.E., MD, Franke, Andre, PhD, Degenhardt, Frauke, MSc, Lieb, Wolfgang, PhD, Gieger, Christian, PhD, Kabesch, Michael, MD, Nöthen, Markus M., MD, Irvine, Alan D., MD, McLean, W.H. Irwin, PhD, Deckert, Stefanie, MPH, Stephan, Victoria, Schwarz, Peter, MD, Aringer, Martin, MD, Novak, Natalija, MD, Weidinger, Stephan, MD, MaHM
Published in Journal of allergy and clinical immunology (01.01.2016)
Published in Journal of allergy and clinical immunology (01.01.2016)
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Journal Article
Host genetic factors related to innate immunity, environmental sensing and cellular functions are associated with human skin microbiota
Moitinho-Silva, Lucas, Degenhardt, Frauke, Rodriguez, Elke, Emmert, Hila, Juzenas, Simonas, Möbus, Lena, Uellendahl-Werth, Florian, Sander, Nicole, Baurecht, Hansjörg, Tittmann, Lukas, Lieb, Wolfgang, Gieger, Christian, Peters, Annette, Ellinghaus, David, Bang, Corinna, Franke, Andre, Weidinger, Stephan, Rühlemann, Malte Christoph
Published in Nature communications (19.10.2022)
Published in Nature communications (19.10.2022)
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Journal Article
Construction and benchmarking of a multi-ethnic reference panel for the imputation of HLA class I and II alleles
Degenhardt, Frauke, Wendorff, Mareike, Wittig, Michael, Ellinghaus, Eva, Datta, Lisa W, Schembri, John, Ng, Siew C, Rosati, Elisa, Hübenthal, Matthias, Ellinghaus, David, Jung, Eun Suk, Lieb, Wolfgang, Abedian, Shifteh, Malekzadeh, Reza, Cheon, Jae Hee, Ellul, Pierre, Sood, Ajit, Midha, Vandana, Thelma, B K, Wong, Sunny H, Schreiber, Stefan, Yamazaki, Keiko, Kubo, Michiaki, Boucher, Gabrielle, Rioux, John D, Lenz, Tobias L, Brant, Steven R, Franke, Andre
Published in Human molecular genetics (15.06.2019)
Published in Human molecular genetics (15.06.2019)
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Journal Article
Immunopeptidomics toolkit library (IPTK): a python-based modular toolbox for analyzing immunopeptidomics data
ElAbd, Hesham, Degenhardt, Frauke, Koudelka, Tomas, Kamps, Ann-Kristin, Tholey, Andreas, Bacher, Petra, Lenz, Tobias L, Franke, Andre, Wendorff, Mareike
Published in BMC bioinformatics (17.08.2021)
Published in BMC bioinformatics (17.08.2021)
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Journal Article
Serum anti-glycan-antibodies in relatives of patients with inflammatory bowel disease
Kamm, Florian, Strauch, Ulrike, Degenhardt, Frauke, Lopez, Rocio, Kunst, Claudia, Rogler, Gerhard, Franke, Andre, Klebl, Frank, Rieders, Florian
Published in PloS one (29.03.2018)
Published in PloS one (29.03.2018)
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Journal Article
Correction: Serum anti-glycan-antibodies in relatives of patients with inflammatory bowel disease
Kamm, Florian, Strauch, Ulrike, Degenhardt, Frauke, Lopez, Rocio, Kunst, Claudia, Rogler, Gerhard, Franke, Andre, Klebl, Frank, Rieder, Florian
Published in PloS one (04.09.2018)
Published in PloS one (04.09.2018)
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Journal Article
Unbiased Characterization of Peptide-HLA Class II Interactions Based on Large-Scale Peptide Microarrays; Assessment of the Impact on HLA Class II Ligand and Epitope Prediction
Wendorff, Mareike, Garcia Alvarez, Heli M, Østerbye, Thomas, ElAbd, Hesham, Rosati, Elisa, Degenhardt, Frauke, Buus, Søren, Franke, Andre, Nielsen, Morten
Published in Frontiers in immunology (05.08.2020)
Published in Frontiers in immunology (05.08.2020)
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Journal Article
Transethnic analysis of psoriasis susceptibility in South Asians and Europeans enhances fine mapping in the MHC and genome wide
Stuart, Philip E., Tsoi, Lam C., Nair, Rajan P., Ghosh, Manju, Kabra, Madhulika, Shaiq, Pakeeza A., Raja, Ghazala K., Qamar, Raheel, Thelma, B.K., Patrick, Matthew T., Parihar, Anita, Singh, Sonam, Khandpur, Sujay, Kumar, Uma, Wittig, Michael, Degenhardt, Frauke, Tejasvi, Trilokraj, Voorhees, John J., Weidinger, Stephan, Franke, Andre, Abecasis, Goncalo R., Sharma, Vinod K., Elder, James T.
Published in HGG advances (13.01.2022)
Published in HGG advances (13.01.2022)
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Journal Article
Sparse Modeling Reveals miRNA Signatures for Diagnostics of Inflammatory Bowel Disease
Hübenthal, Matthias, Hemmrich-Stanisak, Georg, Degenhardt, Frauke, Szymczak, Silke, Du, Zhipei, Elsharawy, Abdou, Keller, Andreas, Schreiber, Stefan, Franke, Andre
Published in PloS one (14.10.2015)
Published in PloS one (14.10.2015)
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Journal Article
Atopic Dermatitis Is an IL-13–Dominant Disease with Greater Molecular Heterogeneity Compared to Psoriasis
Tsoi, Lam C., Rodriguez, Elke, Degenhardt, Frauke, Baurecht, Hansjörg, Wehkamp, Ulrike, Volks, Natalie, Szymczak, Silke, Swindell, William R., Sarkar, Mrinal K., Raja, Kalpana, Shao, Shuai, Patrick, Matthew, Gao, Yilin, Uppala, Ranjitha, Perez White, Bethany E, Getsios, Spiro, Harms, Paul W., Maverakis, Emanual, Elder, James T., Franke, Andre, Gudjonsson, Johann E., Weidinger, Stephan
Published in Journal of investigative dermatology (01.07.2019)
Published in Journal of investigative dermatology (01.07.2019)
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Journal Article
Genome-wide association study in 8,956 German individuals identifies influence of ABO histo-blood groups on gut microbiome
Rühlemann, Malte Christoph, Hermes, Britt Marie, Bang, Corinna, Doms, Shauni, Moitinho-Silva, Lucas, Thingholm, Louise Bruun, Frost, Fabian, Degenhardt, Frauke, Wittig, Michael, Kässens, Jan, Weiss, Frank Ulrich, Peters, Annette, Neuhaus, Klaus, Völker, Uwe, Völzke, Henry, Homuth, Georg, Weiss, Stefan, Grallert, Harald, Laudes, Matthias, Lieb, Wolfgang, Haller, Dirk, Lerch, Markus M., Baines, John F., Franke, Andre
Published in Nature genetics (01.02.2021)
Published in Nature genetics (01.02.2021)
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Journal Article
Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota
Wang, Jun, Thingholm, Louise B, Skiecevičienė, Jurgita, Rausch, Philipp, Kummen, Martin, Hov, Johannes R, Degenhardt, Frauke, Heinsen, Femke-Anouska, Rühlemann, Malte C, Szymczak, Silke, Holm, Kristian, Esko, Tönu, Sun, Jun, Pricop-Jeckstadt, Mihaela, Al-Dury, Samer, Bohov, Pavol, Bethune, Jörn, Sommer, Felix, Ellinghaus, David, Berge, Rolf K, Hübenthal, Matthias, Koch, Manja, Schwarz, Karin, Rimbach, Gerald, Hübbe, Patricia, Pan, Wei-Hung, Sheibani-Tezerji, Raheleh, Häsler, Robert, Rosenstiel, Philipp, D'Amato, Mauro, Cloppenborg-Schmidt, Katja, Künzel, Sven, Laudes, Matthias, Marschall, Hanns-Ulrich, Lieb, Wolfgang, Nöthlings, Ute, Karlsen, Tom H, Baines, John F, Franke, Andre
Published in Nature genetics (01.11.2016)
Published in Nature genetics (01.11.2016)
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Journal Article
Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality
Nakanishi, Tomoko, Pigazzini, Sara, Degenhardt, Frauke, Cordioli, Mattia, Butler-Laporte, Guillaume, Maya-Miles, Douglas, Nafría-Jiménez, Beatriz, Bouysran, Youssef, Niemi, Mari, Palom, Adriana, Ellinghaus, David, Khan, Atlas, Martínez-Bueno, Manuel, Rolker, Selina, Amitano, Sara, Tato, Luisa Roade, Fava, Francesca, Spinner, Christoph D, Prati, Daniele, Bernardo, David, Garcia, Federico, Darcis, Gilles, Fernández-Cadenas, Israel, Holter, Jan Cato, Banales, Jesus, Frithiof, Robert, Kiryluk, Krzysztof, Duga, Stefano, Asselta, Rosanna, Pereira, Alexandre C, Romero-Gómez, Manuel, Bujanda, Luis, Hov, Johannes R, Migeotte, Isabelle, Renieri, Alessandra, Planas, Anna M, Ludwig, Kerstin U, Buti, Maria, Rahmouni, Souad, Alarcón-Riquelme, Marta E, Schulte, Eva C, Franke, Andre, Karlsen, Tom H, Valenti, Luca, Zeberg, Hugo, Richards, J Brent, Ganna, Andrea
Published in The Journal of clinical investigation (01.12.2021)
Published in The Journal of clinical investigation (01.12.2021)
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Crohn’s-associated invariant T cells (CAITs) recognise small sulfonate molecules on CD1d
Minervina, Anastasia A, Pogorelyy, Mikhail V, Paysen, Steffen, Luening, Ulrich, Degenhardt, Frauke, Franke, Andre, Thomas, Paul G, Rosati, Elisa
Published in Gut (01.01.2024)
Published in Gut (01.01.2024)
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Journal Article
Genetic Factors Interact With Tobacco Smoke to Modify Risk for Inflammatory Bowel Disease in Humans and Mice
Yadav, Pankaj, Ellinghaus, David, Rémy, Gaëlle, Freitag-Wolf, Sandra, Cesaro, Anabelle, Degenhardt, Frauke, Boucher, Gabrielle, Delacre, Myriam, Peyrin-Biroulet, Laurent, Pichavant, Muriel, Rioux, John D, Gosset, Philippe, Franke, Andre, Schumm, L. Philip, Krawczak, Michael, Chamaillard, Mathias, Dempfle, Astrid, Andersen, Vibeke
Published in Gastroenterology (New York, N.Y. 1943) (01.08.2017)
Published in Gastroenterology (New York, N.Y. 1943) (01.08.2017)
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Journal Article
Developmental hemostasis: A lifespan from neonates and pregnancy to the young and elderly adult in a European white population
Nowak-Göttl, Ulrike, Limperger, Verena, Kenet, Gili, Degenhardt, Frauke, Arlt, Roman, Domschikowski, Justus, Clausnizer, Hartmut, Liebsch, Jürgen, Junker, Ralf, Steppat, Dagmar
Published in Blood cells, molecules, & diseases (01.09.2017)
Published in Blood cells, molecules, & diseases (01.09.2017)
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Journal Article
A novel unconventional T cell population enriched in Crohn’s disease
Rosati, Elisa, Rios Martini, Gabriela, Pogorelyy, Mikhail V, Minervina, Anastasia A, Degenhardt, Frauke, Wendorff, Mareike, Sari, Soner, Mayr, Gabriele, Fazio, Antonella, Dowds, Christel Marie, Hauser, Charlotte, Tran, Florian, von Schönfels, Witigo, Pochhammer, Julius, Salnikova, Maria A, Jaeckel, Charlot, Gigla, Johannes Boy, Sabet, Sanaz Sedghpour, Hübenthal, Matthias, Schiminsky, Esther, Schreiber, Stefan, Rosenstiel, Philip C, Scheffold, Alexander, Thomas, Paul G, Lieb, Wolfgang, Bokemeyer, Bernd, Witte, Maria, Aden, Konrad, Hendricks, Alexander, Schafmayer, Clemens, Egberts, Jan-Hendrick, Mamedov, Ilgar Z, Bacher, Petra, Franke, Andre
Published in Gut (01.11.2022)
Published in Gut (01.11.2022)
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Journal Article
SARS-CoV-2 Nsp13 encodes for an HLA-E-stabilizing peptide that abrogates inhibition of NKG2A-expressing NK cells
Hammer, Quirin, Dunst, Josefine, Christ, Wanda, Picarazzi, Francesca, Wendorff, Mareike, Momayyezi, Pouria, Huhn, Oisín, Netskar, Herman K., Maleki, Kimia T., García, Marina, Sekine, Takuya, Sohlberg, Ebba, Azzimato, Valerio, Aouadi, Myriam, Degenhardt, Frauke, Franke, Andre, Spallotta, Francesco, Mori, Mattia, Michaëlsson, Jakob, Björkström, Niklas K., Rückert, Timo, Romagnani, Chiara, Horowitz, Amir, Klingström, Jonas, Ljunggren, Hans-Gustaf, Malmberg, Karl-Johan
Published in Cell reports (Cambridge) (08.03.2022)
Published in Cell reports (Cambridge) (08.03.2022)
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