Signal Transduction by Epidermal Growth Factor Occurs through the Subclass of High Affinity Receptors
Defize, L. H. K., Boonstra, J., Meisenhelder, J., Kruijer, W., Tertoolen, L. G. J., Tilly, B. C., Hunter, T., P. M. P. van Bergen en Henegouwen, Moolenaar, W. H., de Laat, S. W.
Published in The Journal of cell biology (01.11.1989)
Published in The Journal of cell biology (01.11.1989)
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Journal Article
A point mutation at the ATP‐binding site of the EGF‐receptor abolishes signal transduction
Moolenaar, W. H., Bierman, A. J., Tilly, B. C., Verlaan, I., Defize, L. H., Honegger, A. M., Ullrich, A., Schlessinger, J.
Published in The EMBO journal (01.03.1988)
Published in The EMBO journal (01.03.1988)
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Journal Article
PTH/PTHrP Receptor in Early Development and Indian Hedgehog-Regulated Bone Growth
Lanske, Beate, Karaplis, Andrew C., Lee, Kaechong, Luz, Arne, Vortkamp, Andrea, Pirro, Alison, Karperien, Marcel, Libert H. K. Defize, Ho, Chrystal, Mulligan, Richard C., Abou-Samra, Abdul-Badi, Jüppner, Harald, Segre, Gino V., Kronenberg, Henry M.
Published in Science (American Association for the Advancement of Science) (02.08.1996)
Published in Science (American Association for the Advancement of Science) (02.08.1996)
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Journal Article
Antibody-induced dimerization activates the epidermal growth factor receptor tyrosine kinase
SPAARGAREN, M, DEFIZE, L. H. K, BOONSTRA, J, DE LAAT, S. W
Published in The Journal of biological chemistry (25.01.1991)
Published in The Journal of biological chemistry (25.01.1991)
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Journal Article
Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity
Boyle, William J., Smeal, Tod, Defize, Libert H.K., Angel, Peter, Woodgett, James R., Karin, Michael, Hunter, Tony
Published in Cell (08.02.1991)
Published in Cell (08.02.1991)
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Journal Article
A431 Cell Variants Lacking the Blood Group A Antigen Display Increased High Affinity Epidermal Growth Factor-Receptor Number, Protein-Tyrosine Kinase Activity, and Receptor Turnover
Defize, L. H. K., Arndt-Jovin, D. J., Jovin, T. M., Boonstra, J., Meisenhelder, J., Hunter, T., de Hey, H. T., de Laat, S. W.
Published in The Journal of cell biology (01.09.1988)
Published in The Journal of cell biology (01.09.1988)
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Journal Article
Identification of connexin43 as a functional target for Wnt signalling
van der Heyden, M A, Rook, M B, Hermans, M M, Rijksen, G, Boonstra, J, Defize, L H, Destrée, O H
Published in Journal of cell science (01.06.1998)
Published in Journal of cell science (01.06.1998)
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Journal Article
Ionic signalling by growth factor receptors
MOOLENAAR, W. H, DEFIZE, L. H. K, DE LAAT, S. W
Published in Journal of experimental biology (01.09.1986)
Published in Journal of experimental biology (01.09.1986)
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Conference Proceeding
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Parathyroid Hormone-Related Peptide as an Endogenous Inducer of Parietal Endoderm Differentiation
van de Stolpe, Anja, Karperien, Marcel, Clemens W. G. M. Löwik, Jüppner, Harald, Segre, Gino V., Abou-Samra, Abdul-Badi, de Laat, Siegfried W., Libert H. K. Defize
Published in The Journal of cell biology (01.01.1993)
Published in The Journal of cell biology (01.01.1993)
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Journal Article
The Rat, Mouse and Human Genes Encoding the Receptor for Parathyroid Hormone and Parathyroid Hormone-Related Peptide Are Highly Homologous
Kong, X.F., Schipani, E., Lanske, B., Joun, H., Karperien, M., Defize, L.H.K., Juppner, H., Potts, J.T., Segre, G.V., Kronenberg, H.M., Abousamra, A.B.
Published in Biochemical and biophysical research communications (16.05.1994)
Published in Biochemical and biophysical research communications (16.05.1994)
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Journal Article
Characterization and identification of an epidermal-growth-factor-activated phospholipase A2
Spaargaren, M, Wissink, S, Defize, L H, de Laat, S W, Boonstra, J
Published in Biochemical journal (01.10.1992)
Published in Biochemical journal (01.10.1992)
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Journal Article
Antibody-induced activation of the epidermal growth factor receptor tyrosine kinase requires the presence of detergent
Spaargaren, Marcel, Defize, Libert H.K., de Laat, Siegfried W., Boonstra, Johannes
Published in Biochemical and biophysical research communications (14.09.1990)
Published in Biochemical and biophysical research communications (14.09.1990)
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Journal Article
Expression pattern of parathyroid hormone/parathyroid hormone related peptide receptor mRNA in mouse postimplantation embryos indicates involvement in multiple developmental processes
Karperien, Marcel, van Dijk, Thamar B., Hoeijmakers, Truus, Cremers, Fons, Abou-Samra, Abdul-Badi, Boonstra, Johannes, de Laat, Siegfried W., Defize, Libert H.K.
Published in Mechanisms of development (01.07.1994)
Published in Mechanisms of development (01.07.1994)
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Journal Article
Dynamics of epidermal growth factor receptor internalization studied by Nanovid light microscopy and electron microscopy in combination with immunogold labeling
van 't Hof, R J, Defize, L H, Nuijdens, R, de Brabander, M, Verkleij, A J, Boonstra, J
Published in European journal of cell biology (01.02.1989)
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Published in European journal of cell biology (01.02.1989)
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