Towards a new combination therapy for tuberculosis with next generation benzothiazinones
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Published in EMBO molecular medicine (01.03.2014)
Published in EMBO molecular medicine (01.03.2014)
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Therapeutic Drug Monitoring of Newer Antiepileptic Drugs: A Randomized Trial for Dosage Adjustment
Aícua‐Rapún, Irene, André, Pascal, Rossetti, Andrea O., Ryvlin, Philippe, Hottinger, Andreas F., Decosterd, Laurent A., Buclin, Thierry, Novy, Jan
Published in Annals of neurology (01.01.2020)
Published in Annals of neurology (01.01.2020)
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Therapeutic Drug Monitoring of Targeted Anticancer Protein Kinase Inhibitors in Routine Clinical Use: A Critical Review
Cardoso, Evelina, Guidi, Monia, Blanchet, Benoît, Schneider, Marie Paule, Decosterd, Laurent A, Buclin, Thierry, Csajka, Chantal, Widmer, Nicolas
Published in Therapeutic drug monitoring (01.02.2020)
Published in Therapeutic drug monitoring (01.02.2020)
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Tamoxifen prolongs survival and alleviates symptoms in mice with fatal X-linked myotubular myopathy
Gayi, Elinam, Neff, Laurence A., Massana Muñoz, Xènia, Ismail, Hesham M., Sierra, Marta, Mercier, Thomas, Décosterd, Laurent A., Laporte, Jocelyn, Cowling, Belinda S., Dorchies, Olivier M., Scapozza, Leonardo
Published in Nature communications (19.11.2018)
Published in Nature communications (19.11.2018)
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No renal dysfunction or salt and water retention in acute mountain sickness at 4,559 m among young resting males after passive ascent
Biollaz, Jérôme, Buclin, Thierry, Hildebrandt, Wulf, Décosterd, Laurent A, Nussberger, Jürg, Swenson, Erik R, Bärtsch, Peter
Published in Journal of applied physiology (1985) (01.01.2021)
Published in Journal of applied physiology (1985) (01.01.2021)
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Anticancer Activities of Novel Nicotinamide Phosphoribosyltransferase Inhibitors in Hematological Malignancies
Biniecka, Paulina, Matsumoto, Saki, Belotti, Axel, Joussot, Jessie, Bai, Jian Fei, Majjigapu, Somi Reddy, Thoueille, Paul, Spaggiari, Dany, Desfontaine, Vincent, Piacente, Francesco, Bruzzone, Santina, Cea, Michele, Decosterd, Laurent A, Vogel, Pierre, Nencioni, Alessio, Duchosal, Michel A, Nahimana, Aimable
Published in Molecules (Basel, Switzerland) (01.02.2023)
Published in Molecules (Basel, Switzerland) (01.02.2023)
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Seizure freedom and plasma levels of newer generation antiseizure medications
Aícua‐Rapún, Irene, André, Pascal, Rossetti, Andrea O., Décosterd, Laurent A., Buclin, Thierry, Novy, Jan
Published in Acta neurologica Scandinavica (01.08.2021)
Published in Acta neurologica Scandinavica (01.08.2021)
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Inhibition of vascular calcification by inositol phosphates derivatized with ethylene glycol oligomers
Schantl, Antonia E., Verhulst, Anja, Neven, Ellen, Behets, Geert J., D’Haese, Patrick C., Maillard, Marc, Mordasini, David, Phan, Olivier, Burnier, Michel, Spaggiari, Dany, Decosterd, Laurent A., MacAskill, Mark G., Alcaide-Corral, Carlos J., Tavares, Adriana A. S., Newby, David E., Beindl, Victoria C., Maj, Roberto, Labarre, Anne, Hegde, Chrismita, Castagner, Bastien, Ivarsson, Mattias E., Leroux, Jean-Christophe
Published in Nature communications (05.02.2020)
Published in Nature communications (05.02.2020)
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Population Pharmacokinetics of Atazanavir in Patients with Human Immunodeficiency Virus Infection
COLOMBO, Sara, BUCLIN, Thierry, CAVASSINI, Matthias, DECOSTERD, Laurent A, TELENTI, Amalio, BIOLLAZ, Jérome, CSAJKA, Chantal
Published in Antimicrobial Agents and Chemotherapy (01.11.2006)
Published in Antimicrobial Agents and Chemotherapy (01.11.2006)
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Precision Oncology by Point-of-Care Therapeutic Drug Monitoring and Dosage Adjustment of Conventional Cytotoxic Chemotherapies: A Perspective
Briki, Myriam, André, Pascal, Thoma, Yann, Widmer, Nicolas, Wagner, Anna D, Decosterd, Laurent A, Buclin, Thierry, Guidi, Monia, Carrara, Sandro
Published in Pharmaceutics (01.04.2023)
Published in Pharmaceutics (01.04.2023)
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An inhibitor of HIV-1 protease modulates constitutive eIF2α dephosphorylation to trigger a specific integrated stress response
De Gassart, Aude, Bujisic, Bojan, Zaffalon, Léa, Decosterd, Laurent A., Di Micco, Antonia, Frera, Gianluca, Tallant, Rémy, Martinon, Fabio
Published in Proceedings of the National Academy of Sciences - PNAS (12.01.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (12.01.2016)
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The Anticancer Drug Tamoxifen Counteracts the Pathology in a Mouse Model of Duchenne Muscular Dystrophy
Dorchies, Olivier M, Reutenauer-Patte, Julie, Dahmane, Elyes, Ismail, Hesham M, Petermann, Olivier, Patthey-Vuadens, Ophélie, Comyn, Sophie A, Gayi, Elinam, Piacenza, Tony, Handa, Robert J, Décosterd, Laurent A, Ruegg, Urs T
Published in The American journal of pathology (01.02.2013)
Published in The American journal of pathology (01.02.2013)
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Efficacy and safety of dolutegravir plus emtricitabine versus standard ART for the maintenance of HIV-1 suppression: 48-week results of the factorial, randomized, non-inferiority SIMPL'HIV trial
Sculier, Delphine, Wandeler, Gilles, Yerly, Sabine, Marinosci, Annalisa, Stoeckle, Marcel, Bernasconi, Enos, Braun, Dominique L, Vernazza, Pietro, Cavassini, Matthias, Buzzi, Marta, Metzner, Karin J, Decosterd, Laurent A, Günthard, Huldrych F, Schmid, Patrick, Limacher, Andreas, Egger, Matthias, Calmy, Alexandra
Published in PLoS medicine (10.11.2020)
Published in PLoS medicine (10.11.2020)
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Development and validation of a multiplex UHPLC-MS/MS method for the determination of the investigational antibiotic against multi-resistant tuberculosis macozinone (PBTZ169) and five active metabolites in human plasma
Spaggiari, Dany, Desfontaine, Vincent, Cruchon, Sandra, Guinchard, Sylvie, Vocat, Anthony, Blattes, Emilyne, Pitteloud, Jeff, Ciullini, Lorenzo, Bardinet, Carine, Ivanyuk, Anton, Makarov, Vadim, Ryabova, Olga, Buclin, Thierry, Cole, Stewart T, Decosterd, Laurent A
Published in PloS one (31.05.2019)
Published in PloS one (31.05.2019)
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Plasma and Cerebrospinal Fluid Population Pharmacokinetics of Temozolomide in Malignant Glioma Patients
OSTERMANN, Sandrine, CSAJKA, Chantal, BUCLIN, Thierry, LEYVRAZ, Serge, LEJEUNE, Ferdy, DECOSTERD, Laurent A, STUPP, Roger
Published in Clinical cancer research (01.06.2004)
Published in Clinical cancer research (01.06.2004)
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A validated assay by liquid chromatography-tandem mass spectrometry for the simultaneous quantification of elvitegravir and rilpivirine in HIV positive patients
Aouri, Manel, Calmy, Alexandra, Hirschel, Bernard, Telenti, Amalio, Buclin, Thierry, Cavassini, Matthias, Rauch, Andri, Decosterd, Laurent A.
Published in Journal of mass spectrometry. (01.05.2013)
Published in Journal of mass spectrometry. (01.05.2013)
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Population pharmacokinetics and pharmacodynamics of the artesunate-mefloquine fixed dose combination for the treatment of uncomplicated falciparum malaria in African children
Guidi, Monia, Mercier, Thomas, Aouri, Manel, Decosterd, Laurent A, Csajka, Chantal, Ogutu, Bernhards, Carn, Gwénaëlle, Kiechel, Jean-René
Published in Malaria journal (18.04.2019)
Published in Malaria journal (18.04.2019)
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