An open conformation of ADAMTS‐13 is a hallmark of acute acquired thrombotic thrombocytopenic purpura
Roose, E., Schelpe, A. S., Joly, B. S., Peetermans, M., Verhamme, P., Voorberg, J., Greinacher, A., Deckmyn, H., De Meyer, S. F., Coppo, P., Veyradier, A., Vanhoorelbeke, K.
Published in Journal of thrombosis and haemostasis (01.02.2018)
Published in Journal of thrombosis and haemostasis (01.02.2018)
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Journal Article
Linker regions and flexibility around the metalloprotease domain account for conformational activation of ADAMTS‐13
Deforche, L., Roose, E., Vandenbulcke, A., Vandeputte, N., Feys, H. B., Springer, T. A., Mi, L. Z., Muia, J., Sadler, J. E., Soejima, K., Rottensteiner, H., Deckmyn, H., De Meyer, S. F., Vanhoorelbeke, K.
Published in Journal of thrombosis and haemostasis (01.11.2015)
Published in Journal of thrombosis and haemostasis (01.11.2015)
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High and long‐term von Willebrand factor expression after Sleeping Beauty transposon‐mediated gene therapy in a mouse model of severe von Willebrand disease
Portier, I., Vanhoorelbeke, K., Verhenne, S., Pareyn, I., Vandeputte, N., Deckmyn, H., Goldenberg, D. S., Samal, H. B., Singh, M., Ivics, Z., Izsvák, Z., De Meyer, S. F.
Published in Journal of thrombosis and haemostasis (01.03.2018)
Published in Journal of thrombosis and haemostasis (01.03.2018)
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Amplified endogenous plasmin activity resolves acute thrombotic thrombocytopenic purpura in mice
Tersteeg, C., Joly, B. S., Gils, A., Lijnen, R., Deckmyn, H., Declerck, P. J., Plaimauer, B., Coppo, P., Veyradier, A., Maas, C., De Meyer, S. F., Vanhoorelbeke, K.
Published in Journal of thrombosis and haemostasis (01.12.2017)
Published in Journal of thrombosis and haemostasis (01.12.2017)
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Journal Article
The novel ADAMTS13‐p.D187H mutation impairs ADAMTS13 activity and secretion and contributes to thrombotic thrombocytopenic purpura in mice
De Cock, E., Hermans, C., De Raeymaecker, J., De Ceunynck, K., De Maeyer, B., Vandeputte, N., Vandenbulcke, A., Deckmyn, H., Rottensteiner, H., De Maeyer, M., De Meyer, S. F., Vanhoorelbeke, K.
Published in Journal of thrombosis and haemostasis (01.02.2015)
Published in Journal of thrombosis and haemostasis (01.02.2015)
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Deletion of GARP on mouse regulatory T cells is not sufficient to inhibit the growth of transplanted tumors
Vermeersch, E., Liénart, S., Collignon, A., Lucas, S., Gallimore, A., Gysemans, C., Unutmaz, D., Vanhoorelbeke, K., De Meyer, S.F., Maes, W., Deckmyn, H.
Published in Cellular immunology (01.10.2018)
Published in Cellular immunology (01.10.2018)
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Multiple ways to switch platelet integrins on and off
COSEMANS, J. M. E. M., ISERBYT, B. F., DECKMYN, H., HEEMSKERK, J. W. M.
Published in Journal of thrombosis and haemostasis (01.08.2008)
Published in Journal of thrombosis and haemostasis (01.08.2008)
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Inactivation of ADAMTS13 by plasmin as a potential cause of thrombotic thrombocytopenic purpura
FEYS, H. B., VANDEPUTTE, N., PALLA, R., PEYVANDI, F., PEERLINCK, K., DECKMYN, H., LIJNEN, H. R., VANHOORELBEKE, K.
Published in Journal of thrombosis and haemostasis (01.09.2010)
Published in Journal of thrombosis and haemostasis (01.09.2010)
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Desmopressin treatment improves platelet function under flow in patients with postoperative bleeding
Swieringa, F., Lancé, M. D., Fuchs, B., Feijge, M. A. H., Solecka, B. A., Verheijen, L. P. J., Hughes, K. R., Oerle, R., Deckmyn, H., Kannicht, C., Heemskerk, J. W. M., Meijden, P. E. J.
Published in Journal of thrombosis and haemostasis (01.08.2015)
Published in Journal of thrombosis and haemostasis (01.08.2015)
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In vivo von Willebrand factor size heterogeneity in spite of the clinical deficiency of ADAMTS‐13
DE MEYER, S. F., BUDDE, U., DECKMYN, H., VANHOORELBEKE, K.
Published in Journal of thrombosis and haemostasis (01.12.2011)
Published in Journal of thrombosis and haemostasis (01.12.2011)
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The distal carboxyterminal domains of murine ADAMTS13 influence proteolysis of platelet‐decorated VWF strings in vivo
DE MAEYER, B., DE MEYER, S. F., FEYS, H. B., PAREYN, I., VANDEPUTTE, N., DECKMYN, H., VANHOORELBEKE, K.
Published in Journal of thrombosis and haemostasis (01.10.2010)
Published in Journal of thrombosis and haemostasis (01.10.2010)
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ADAMTS‐13 plasma level determination uncovers antigen absence in acquired thrombotic thrombocytopenic purpura and ethnic differences
FEYS, H. B., LIU, F., DONG, N., PAREYN, I., VAUTERIN, S., VANDEPUTTE, N., NOPPE, W., RUAN, C., DECKMYN, H., VANHOORELBEKE, K.
Published in Journal of thrombosis and haemostasis (01.05.2006)
Published in Journal of thrombosis and haemostasis (01.05.2006)
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Macroporous monolithic gels, cryogels, with immobilized phages from phage-display library as a new platform for fast development of affinity adsorbent capable of target capture from crude feeds
Noppe, Wim, Plieva, Fatima M., Vanhoorelbeke, Karen, Deckmyn, Hans, Tuncel, Mürvet, Tuncel, Ali, Galaev, Igor Yu, Mattiasson, Bo
Published in Journal of biotechnology (15.09.2007)
Published in Journal of biotechnology (15.09.2007)
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Blockade of Glycoproteins Ib and IIb/IIIa Reduces Platelet Sequestration and PVR Rise in a Xenogeneic Lung Perfusion Model
Burdorf, L, Riner, A, Rybak, E, Harris, D, Dahi, S, Zhang, T, Parsell, D, Ali, F, Schwartz, E, Kang, E, Cheng, X, Sievert, E, Braileanu, G, Quinn, K, Shah, A, De Meyer, S, Deckmyn, H, Phelps, C.J, Ayares, D.L, Pierson, R.N, Azimzadeh, A.M
Published in The Journal of heart and lung transplantation (01.04.2015)
Published in The Journal of heart and lung transplantation (01.04.2015)
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295 Combined aGPIb and aGPIIb/IIIa Blockade Prevents Platelet Sequestration in a Pig-to-Human Lung Perfusion Model
Burdorf, L, Zhang, T, Rybak, E, Salles, I.I, Broos, K, Welty, E, Avon, C, Laaris, A, Cheng, X, Ayares, D, Deckmyn, H, Azimzadeh, A.M, Pierson, R.N
Published in The Journal of heart and lung transplantation (01.04.2012)
Published in The Journal of heart and lung transplantation (01.04.2012)
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Identification of a VWF peptide antagonist that blocks platelet adhesion under high shear conditions by selectively inhibiting the VWF‐collagen interaction
SZANTO, T., VANHOORELBEKE, K., TOTH, G., VANDENBULCKE, A., TOTH, J., NOPPE, W., DECKMYN, H., HARSFALVI, J.
Published in Journal of thrombosis and haemostasis (01.10.2009)
Published in Journal of thrombosis and haemostasis (01.10.2009)
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The von Willebrand factor self‐association is modulated by a multiple domain interaction
ULRICHTS, H., VANHOORELBEKE, K., GIRMA, J. P., LENTING, P. J., VAUTERIN, S., DECKMYN, H.
Published in Journal of thrombosis and haemostasis (01.03.2005)
Published in Journal of thrombosis and haemostasis (01.03.2005)
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295 Blocking GP1b-vWF Interaction by Anti-GP1b Fab Reduces Activation and Sequestration of Platelets in a Xenogeneic Pig Lung Perfusion Model
Burdorf, L, Zhang, T, Rybak, E, Salles, I.I, Broos, K, Welty, E, Avon, C, Laaris, A, Cheng, X, Ayares, D, Deckmyn, H, Azimzadeh, A.M, Pierson, R.N
Published in The Journal of heart and lung transplantation (2011)
Published in The Journal of heart and lung transplantation (2011)
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