VAR2CSA binding phenotype has ancient origin and arose before Plasmodium falciparum crossed to humans: implications in placental malaria vaccine design
Gangnard, Stéphane, Chêne, Arnaud, Dechavanne, Sébastien, Srivastava, Anand, Avril, Marion, Smith, Joseph D., Gamain, Benoît
Published in Scientific reports (18.11.2019)
Published in Scientific reports (18.11.2019)
Get full text
Journal Article
Interest of seroprevalence surveys for the epidemiological surveillance of the SARS‐CoV‐2 pandemic in African populations: Insights from the ARIACOV project in Benin
Houngbégnon, Parfait, Nouatin, Odilon, Yadouléton, Anges, Hounkpatin, Benjamin, Fievet, Nadine, Atindégla, Eloïc, Dechavanne, Sébastien, Guichet, Emilande, Ayouba, Ahidjo, Pelloquin, Raphaël, Maman, David, Thaurignac, Guillaume, Peeters, Martine, Aviansou, Annonciat, Sourakafou, Salifou, Delaporte, Eric, Massougbodji, Achille, Cottrell, Gilles
Published in Tropical medicine & international health (01.07.2023)
Published in Tropical medicine & international health (01.07.2023)
Get full text
Journal Article
Structure of the DBL3X-DBL4ε region of the VAR2CSA placental malaria vaccine candidate: insight into DBL domain interactions
Gangnard, Stéphane, Lewit-Bentley, Anita, Dechavanne, Sébastien, Srivastava, Anand, Amirat, Faroudja, Bentley, Graham A., Gamain, Benoît
Published in Scientific reports (09.10.2015)
Published in Scientific reports (09.10.2015)
Get full text
Journal Article
Beninese children with cerebral malaria do not develop humoral immunity against the IT4-VAR19-DC8 PfEMP1 variant linked to EPCR and brain endothelial binding
Nunes-Silva, Sofia, Dechavanne, Sébastien, Moussiliou, Azizath, Pstrąg, Natalia, Semblat, Jean-Philippe, Gangnard, Stéphane, Tuikue-Ndam, Nicaise, Deloron, Philippe, Chêne, Arnaud, Gamain, Benoît
Published in Malaria journal (08.12.2015)
Published in Malaria journal (08.12.2015)
Get full text
Journal Article
The proteome of neutrophils in sickle cell disease reveals an unexpected activation of interferon alpha signaling pathway
Hermand, Patricia, Azouzi, Slim, Gautier, Emilie-Fleur, Guillonneau, François, Bondet, Vincent, Duffy, Darragh, Dechavanne, Sebastien, Tharaux, Pierre-Louis, Mayeux, Patrick, Le Van Kim, Caroline, Koehl, Berengere
Published in Haematologica (Roma) (01.12.2020)
Published in Haematologica (Roma) (01.12.2020)
Get full text
Journal Article
PRIMVAC vaccine adjuvanted with Alhydrogel or GLA-SE to prevent placental malaria: a first-in-human, randomised, double-blind, placebo-controlled study
Sirima, Sodiomon B, Richert, Laura, Chêne, Arnaud, Konate, Amadou T, Campion, Cécilia, Dechavanne, Sébastien, Semblat, Jean-Philippe, Benhamouda, Nadine, Bahuaud, Mathilde, Loulergue, Pierre, Ouédraogo, Alphonse, Nébié, Issa, Kabore, Moïse, Kargougou, Désiré, Barry, Aïssata, Ouattara, San Maurice, Boilet, Valérie, Allais, Florence, Roguet, Gwenaelle, Havelange, Nicolas, Lopez-Perez, Elvira, Kuppers, Alexis, Konaté, Eleine, Roussillon, Caroline, Kanté, Myriam, Belarbi, Linda, Diarra, Amidou, Henry, Noelie, Soulama, Issiaka, Ouédraogo, Amidou, Esperou, Helene, Leroy, Odile, Batteux, Frederic, Tartour, Eric, Viebig, Nicola K, Thiebaut, Rodolphe, Launay, Odile, Gamain, Benoît
Published in The Lancet infectious diseases (01.05.2020)
Published in The Lancet infectious diseases (01.05.2020)
Get full text
Journal Article
Monocytes, particularly nonclassical ones, lose their opsonic and nonopsonic phagocytosis capacity during pediatric cerebral malaria
Vianou, Bertin, Royo, Jade, Dechavanne, Sébastien, Bertin, Gwladys I, Yessoufou, Akadiri, Houze, Sandrine, Faucher, Jean-François, Aubouy, Agnes
Published in Frontiers in immunology (21.05.2024)
Published in Frontiers in immunology (21.05.2024)
Get full text
Journal Article
Full-length extracellular region of the var2CSA variant of PfEMP1 is required for specific, high-affinity binding to CSA
Srivastava, Anand, Gangnard, Stéphane, Round, Adam, Dechavanne, Sébastien, Juillerat, Alexandre, Raynal, Bertrand, Faure, Grazyna, Baron, Bruno, Ramboarina, Stéphanie, Singh, Saurabh Kumar, Belrhali, Hassan, England, Patrick, Lewit-Bentley, Anita, Scherf, Artur, Bentley, Graham A, Gamain, Benoît
Published in Proceedings of the National Academy of Sciences - PNAS (16.03.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (16.03.2010)
Get full text
Journal Article
Phosphorylation of the VAR2CSA extracellular region is associated with enhanced adhesive properties to the placental receptor CSA
Dorin-Semblat, Dominique, Tétard, Marilou, Claës, Aurélie, Semblat, Jean-Philippe, Dechavanne, Sébastien, Fourati, Zaineb, Hamelin, Romain, Armand, Florence, Matesic, Graziella, Nunes-Silva, Sofia, Srivastava, Anand, Gangnard, Stéphane, Lopez-Rubio, Jose-Juan, Moniatte, Marc, Doerig, Christian, Scherf, Artur, Gamain, Benoît
Published in PLoS biology (10.06.2019)
Published in PLoS biology (10.06.2019)
Get full text
Journal Article
Placental cytokine and chemokine profiles reflect pregnancy outcomes in women exposed to Plasmodium falciparum infection
Chêne, Arnaud, Briand, Valérie, Ibitokou, Samad, Dechavanne, Sébastien, Massougbodji, Achille, Deloron, Philippe, Luty, Adrian J F, Gamain, Benoît, Fievet, Nadine
Published in Infection and immunity (01.09.2014)
Published in Infection and immunity (01.09.2014)
Get full text
Journal Article
Influence of the Timing of Malaria Infection during Pregnancy on Birth Weight and on Maternal Anemia in Benin
HUYNH, Bich-Tram, FIEVET, Nadine, GBAGUIDI, Gildas, DECHAVANNE, Sebastien, BORGELLA, Sophie, GUEZO-MEVO, Blaise, MASSOUGBODJI, Achille, NICAISE TUIKUE NDAM, DELORON, Philippe, COT, Michel
Published in The American journal of tropical medicine and hygiene (01.08.2011)
Published in The American journal of tropical medicine and hygiene (01.08.2011)
Get full text
Journal Article
Associations between an IgG3 polymorphism in the binding domain for FcRn, transplacental transfer of malaria-specific IgG3, and protection against Plasmodium falciparum malaria during infancy: A birth cohort study in Benin
Dechavanne, Celia, Dechavanne, Sebastien, Sadissou, Ibrahim, Lokossou, Adjimon Gatien, Alvarado, Fernanda, Dambrun, Magalie, Moutairou, Kabirou, Courtin, David, Nuel, Gregory, Garcia, Andre, Migot-Nabias, Florence, King, Christopher L
Published in PLoS medicine (09.10.2017)
Published in PLoS medicine (09.10.2017)
Get full text
Journal Article
Var2CSA minimal CSA binding region is located within the N-terminal region
Srivastava, Anand, Gangnard, Stéphane, Dechavanne, Sébastien, Amirat, Farroudja, Lewit Bentley, Anita, Bentley, Graham A, Gamain, Benoît
Published in PloS one (19.05.2011)
Published in PloS one (19.05.2011)
Get full text
Journal Article
An image-based high-content screening for compounds targeting Toxoplasma gondii repurposed inhibitors effective against the malaria parasite Plasmodium falciparum
Honfozo, Ariane, Houngue, Rodrigue, Vandeputte, Alexandre, Dechavanne, Sébastien, Nouatin, Odilon, Atindehou, Ménonvè Cynthia, Fanou, Lucie Ayi, Massougbodji, Achille, Dechavanne, Célia, Brodin, Priscille, Tomavo, Stanislas
Published in Frontiers in cellular and infection microbiology (2023)
Published in Frontiers in cellular and infection microbiology (2023)
Get full text
Journal Article
Down-selection of the VAR2CSA DBL1-2 expressed in E. coli as a lead antigen for placental malaria vaccine development
Chêne, Arnaud, Gangnard, Stéphane, Dechavanne, Célia, Dechavanne, Sebastien, Srivastava, Anand, Tétard, Marilou, Hundt, Sophia, Leroy, Odile, Havelange, Nicolas, Viebig, Nicola K., Gamain, Benoît
Published in npj vaccines (17.07.2018)
Published in npj vaccines (17.07.2018)
Get full text
Journal Article
Structural basis for neutralization of Plasmodium vivax by naturally acquired human antibodies that target DBP
Urusova, Darya, Carias, Lenore, Huang, Yining, Nicolete, Vanessa C., Popovici, Jean, Roesch, Camille, Salinas, Nichole D., Dechavanne, Sebastien, Witkowski, Benoit, Ferreira, Marcelo U., Adams, John H., Gross, Michael L., King, Christopher L., Tolia, Niraj H.
Published in Nature microbiology (01.09.2019)
Published in Nature microbiology (01.09.2019)
Get full text
Journal Article
Heterozygous HbAC but not HbAS is associated with higher newborn birthweight among women with pregnancy-associated malaria
Tétard, Marilou, Milet, Jacqueline, Dechavanne, Sébastien, Fievet, Nadine, Dorin-Semblat, Dominique, Elion, Jacques, Fairhurst, Rick M., Deloron, Philippe, Tuikue-Ndam, Nicaise, Gamain, Benoît
Published in Scientific reports (03.05.2017)
Published in Scientific reports (03.05.2017)
Get full text
Journal Article
Parity-dependent recognition of DBL1X-3X suggests an important role of the VAR2CSA high-affinity CSA-binding region in the development of the humoral response against placental malaria
Dechavanne, Sébastien, Srivastava, Anand, Gangnard, Stéphane, Nunes-Silva, Sofia, Dechavanne, Célia, Fievet, Nadine, Deloron, Philippe, Chêne, Arnaud, Gamain, Benoît
Published in Infection and immunity (01.06.2015)
Published in Infection and immunity (01.06.2015)
Get full text
Journal Article
Sickle Cell Trait Modulates the Proteome and Phosphoproteome of Plasmodium falciparum -Infected Erythrocytes
Chauvet, Margaux, Chhuon, Cerina, Lipecka, Joanna, Dechavanne, Sébastien, Dechavanne, Célia, Lohezic, Murielle, Ortalli, Margherita, Pineau, Damien, Ribeil, Jean-Antoine, Manceau, Sandra, Le Van Kim, Caroline, Luty, Adrian J F, Migot-Nabias, Florence, Azouzi, Slim, Guerrera, Ida Chiara, Merckx, Anaïs
Published in Frontiers in cellular and infection microbiology (24.03.2021)
Published in Frontiers in cellular and infection microbiology (24.03.2021)
Get full text
Journal Article
Antibodies to a full-length VAR2CSA immunogen are broadly strain-transcendent but do not cross-inhibit different placental-type parasite isolates
Avril, Marion, Hathaway, Marianne J, Srivastava, Anand, Dechavanne, Sébastien, Hommel, Mirja, Beeson, James G, Smith, Joseph D, Gamain, Benoît
Published in PloS one (07.02.2011)
Published in PloS one (07.02.2011)
Get full text
Journal Article