Development of a high content imaging assay to assess drug induced lysosome perturbation
Baines, I.A., Davis, L.J., Lennon, M.G., Taylor, C.G., Dare, T.O., Bright, N.A., Luzio, J.P., Parry, J.D., Gresham, S.L., Dear, G.J.
Published in Toxicology letters (10.10.2018)
Published in Toxicology letters (10.10.2018)
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An in-vitro investigation in rat L6 and mouse C2C12 cell lines into the skeletal muscle toxicity observed in the mouse of Trypanosoma Cruzi whole cell inhibitor compounds
Grimsditch, D., Brunori, G., Armitage, J., Taylor, C., Dare, T.O., Lennon, M., Jimenez-Navarro, E., Valle, S. Gonzalez-Del, Gresham, S., Lyon, J., Dear, G.J.
Published in Toxicology letters (10.10.2018)
Published in Toxicology letters (10.10.2018)
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Journal Article
Evaluation of preparative high performance liquid chromatography and cryoprobe-nuclear magnetic resonance spectroscopy for the early quantitative estimation of drug metabolites in human plasma
Dear, G.J., Roberts, A.D., Beaumont, C., North, S.E.
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.12.2008)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.12.2008)
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Utilizing a −100 °C microplate CCD Imager, yttrium silicate coated 384-microplates and ultra-performance liquid chromatography for improved profiling of radiolabeled drug metabolites in complex biological samples
Dear, G.J., Patel, N., Weightman, Alan, Pirard, Hans, Talvitie, Miika
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.06.2008)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01.06.2008)
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Journal Article
TopCount coupled to ultra-performance liquid chromatography for the profiling of radiolabeled drug metabolites in complex biological samples
Dear, G.J., Patel, N., Kelly, P.J., Webber, L., Yung, M.
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (21.11.2006)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (21.11.2006)
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The determination of nicotinic acid in plasma by mixed-mode liquid chromatography–tandem mass spectrometry following ion exchange solid phase extraction
Mallett, D.N., Dayal, S., Dear, G.J., Pateman, A.J.
Published in Journal of pharmaceutical and biomedical analysis (03.05.2006)
Published in Journal of pharmaceutical and biomedical analysis (03.05.2006)
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Journal Article
Optimisation and routine use of generic ultra-high flow-rate liquid chromatography with mass spectrometric detection for the direct on-line analysis of pharmaceuticals in plasma
Ayrton, J, Dear, G.J, Leavens, W.J, Mallett, D.N, Plumb, R.S
Published in Journal of Chromatography A (18.12.1998)
Published in Journal of Chromatography A (18.12.1998)
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Conference Proceeding
Mass directed peak selection, an efficient method of drug metabolite identification using directly coupled liquid chromatography–mass spectrometry–nuclear magnetic resonance spectroscopy
Dear, G.J., Plumb, R.S., Sweatman, B.C., Ayrton, J., Lindon, J.C., Nicholson, J.K., Ismail, I.M.
Published in Journal of chromatography. B, Biomedical sciences and applications (01.10.2000)
Published in Journal of chromatography. B, Biomedical sciences and applications (01.10.2000)
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Isolation and characterization of microcystins from laboratory cultures and environmental samples of Microcystis aeruginosa and from an associated animal toxicosis
Lawton, L.A. (Robert Gordan University, Aberdeen, UK.), Edwards, C, Beattie, K.A, Pleasance, S, Dear, G.J, Codd, G.A
Published in Natural toxins (1995)
Published in Natural toxins (1995)
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Use of directly coupled ion-exchange liquid chromatography–mass spectrometry and liquid chromatography–nuclear magnetic resonance spectroscopy as a strategy for polar metabolite identification
Dear, G.J, Plumb, R.S, Sweatman, B.C, Parry, P.S, Roberts, A.D, Lindon, J.C, Nicholson, J.K, Ismail, I.M
Published in Journal of chromatography. B, Biomedical sciences and applications (01.10.2000)
Published in Journal of chromatography. B, Biomedical sciences and applications (01.10.2000)
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