The Fanconi Anemia Pathway Maintains Genome Stability by Coordinating Replication and Transcription
Schwab, Rebekka A., Nieminuszczy, Jadwiga, Shah, Fenil, Langton, Jamie, Lopez Martinez, David, Liang, Chih-Chao, Cohn, Martin A., Gibbons, Richard J., Deans, Andrew J., Niedzwiedz, Wojciech
Published in Molecular cell (05.11.2015)
Published in Molecular cell (05.11.2015)
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Journal Article
FANCM limits ALT activity by restricting telomeric replication stress induced by deregulated BLM and R-loops
Sousa Silva, Bruno Adriano, Pentz, Richard, Figueira, Ana Margarida, Arora, Rajika, Lee, Yong Woo, Hodson, Charlotte, Wischnewski, Harry, Deans, Andrew J., Azzalin, Claus Maria
Published in Nature communications (28.05.2019)
Published in Nature communications (28.05.2019)
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Journal Article
The FANCM-BLM-TOP3A-RMI complex suppresses alternative lengthening of telomeres (ALT)
Lu, Robert, O’Rourke, Julienne J., Sobinoff, Alexander P., Allen, Joshua A. M., Nelson, Christopher B., Tomlinson, Christopher G., Lee, Michael, Reddel, Roger R., Deans, Andrew J., Pickett, Hilda A.
Published in Nature communications (28.05.2019)
Published in Nature communications (28.05.2019)
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Journal Article
Mechanism of Ubiquitination and Deubiquitination in the Fanconi Anemia Pathway
van Twest, Sylvie, Murphy, Vincent J., Hodson, Charlotte, Tan, Winnie, Swuec, Paolo, O’Rourke, Julienne J., Heierhorst, Jörg, Crismani, Wayne, Deans, Andrew J.
Published in Molecular cell (19.01.2017)
Published in Molecular cell (19.01.2017)
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Journal Article
The Architecture and Evolution of Cancer Neochromosomes
Garsed, Dale W., Marshall, Owen J., Corbin, Vincent D.A., Hsu, Arthur, Di Stefano, Leon, Schröder, Jan, Li, Jason, Feng, Zhi-Ping, Kim, Bo W., Kowarsky, Mark, Lansdell, Ben, Brookwell, Ross, Myklebost, Ola, Meza-Zepeda, Leonardo, Holloway, Andrew J., Pedeutour, Florence, Choo, K.H. Andy, Damore, Michael A., Deans, Andrew J., Papenfuss, Anthony T., Thomas, David M.
Published in Cancer cell (10.11.2014)
Published in Cancer cell (10.11.2014)
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Journal Article
Mechanism of structure-specific DNA binding by the FANCM branchpoint translocase
Abbouche, Lara, Murphy, Vincent J, Gao, Jixuan, van Twest, Sylvie, Sobinoff, Alexander P, Auweiler, Karen M, Pickett, Hilda A, Bythell-Douglas, Rohan, Deans, Andrew J
Published in Nucleic acids research (14.10.2024)
Published in Nucleic acids research (14.10.2024)
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Journal Article
Monoubiquitination by the human Fanconi anemia core complex clamps FANCI:FANCD2 on DNA in filamentous arrays
Tan, Winnie, van Twest, Sylvie, Leis, Andrew, Bythell-Douglas, Rohan, Murphy, Vincent J, Sharp, Michael, Parker, Michael W, Crismani, Wayne, Deans, Andrew J
Published in eLife (13.03.2020)
Published in eLife (13.03.2020)
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Journal Article
Identification of KIAA1018/FAN1, a DNA Repair Nuclease Recruited to DNA Damage by Monoubiquitinated FANCD2
MacKay, Craig, Déclais, Anne-Cécile, Lundin, Cecilia, Agostinho, Ana, Deans, Andrew J., MacArtney, Thomas J., Hofmann, Kay, Gartner, Anton, West, Stephen C., Helleday, Thomas, Lilley, David M.J., Rouse, John
Published in Cell (09.07.2010)
Published in Cell (09.07.2010)
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Journal Article
ZNF827 is a single-stranded DNA binding protein that regulates the ATR-CHK1 DNA damage response pathway
Yang, Sile F., Nelson, Christopher B., Wells, Jadon K., Fernando, Madushan, Lu, Robert, Allen, Joshua A. M., Malloy, Lisa, Lamm, Noa, Murphy, Vincent J., Mackay, Joel P., Deans, Andrew J., Cesare, Anthony J., Sobinoff, Alexander P., Pickett, Hilda A.
Published in Nature communications (12.03.2024)
Published in Nature communications (12.03.2024)
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Journal Article
ATP-dependent helicase activity is dispensable for the physiological functions of Recql4
Castillo-Tandazo, Wilson, Smeets, Monique F, Murphy, Vincent, Liu, Rui, Hodson, Charlotte, Heierhorst, Jörg, Deans, Andrew J, Walkley, Carl R
Published in PLoS genetics (01.07.2019)
Published in PLoS genetics (01.07.2019)
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Journal Article
Mechanism of Bloom syndrome complex assembly required for double Holliday junction dissolution and genome stability
Hodson, Charlotte, Low, Jason K K, van Twest, Sylvie, Jones, Samuel E, Swuec, Paolo, Murphy, Vincent, Tsukada, Kaima, Fawkes, Matthew, Bythell-Douglas, Rohan, Davies, Adelina, Holien, Jessica K, O'Rourke, Julienne J, Parker, Benjamin L, Glaser, Astrid, Parker, Michael W, Mackay, Joel P, Blackford, Andrew N, Costa, Alessandro, Deans, Andrew J
Published in Proceedings of the National Academy of Sciences - PNAS (08.02.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (08.02.2022)
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Journal Article
The FA Core Complex Contains a Homo-dimeric Catalytic Module for the Symmetric Mono-ubiquitination of FANCI-FANCD2
Swuec, Paolo, Renault, Ludovic, Borg, Aaron, Shah, Fenil, Murphy, Vincent J., van Twest, Sylvie, Snijders, Ambrosius P., Deans, Andrew J., Costa, Alessandro
Published in Cell reports (Cambridge) (17.01.2017)
Published in Cell reports (Cambridge) (17.01.2017)
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Journal Article
Preparation and purification of mono-ubiquitinated proteins using Avi-tagged ubiquitin
Tan, Winnie, Murphy, Vincent J, Charron, Aude, van Twest, Sylvie, Sharp, Michael, Constantinou, Angelos, Parker, Michael W, Crismani, Wayne, Bythell-Douglas, Rohan, Deans, Andrew J
Published in PloS one (24.02.2020)
Published in PloS one (24.02.2020)
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Journal Article
The DNA translocase activity of FANCM protects stalled replication forks
BLACKFORD, Andrew N, SCHWAB, Rebekka A, NIEMINUSZCZY, Jadwiga, DEANS, Andrew J, WEST, Stephen C, NIEDZWIEDZ, Wojciech
Published in Human molecular genetics (01.05.2012)
Published in Human molecular genetics (01.05.2012)
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Journal Article
FANCM and FAAP24 Function in ATR-Mediated Checkpoint Signaling Independently of the Fanconi Anemia Core Complex
Collis, Spencer J., Ciccia, Alberto, Deans, Andrew J., Hořejší, Zuzana, Martin, Julie S., Maslen, Sarah L., Skehel, J. Mark, Elledge, Stephen J., West, Stephen C., Boulton, Simon J.
Published in Molecular cell (07.11.2008)
Published in Molecular cell (07.11.2008)
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