Relative Mitochondrial Priming of Myeloblasts and Normal HSCs Determines Chemotherapeutic Success in AML
Vo, Thanh-Trang, Ryan, Jeremy, Carrasco, Ruben, Neuberg, Donna, Rossi, Derrick J., Stone, Richard M., DeAngelo, Daniel J., Frattini, Mark G., Letai, Anthony
Published in Cell (12.10.2012)
Published in Cell (12.10.2012)
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Inotuzumab ozogamicin versus standard of care in relapsed or refractory acute lymphoblastic leukemia: Final report and long‐term survival follow‐up from the randomized, phase 3 INO‐VATE study
Kantarjian, Hagop M., DeAngelo, Daniel J., Stelljes, Matthias, Liedtke, Michaela, Stock, Wendy, Gökbuget, Nicola, O’Brien, Susan M., Jabbour, Elias, Wang, Tao, Liang White, Jane, Sleight, Barbara, Vandendries, Erik, Advani, Anjali S.
Published in Cancer (15.07.2019)
Published in Cancer (15.07.2019)
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Ponatinib efficacy and safety in Philadelphia chromosome–positive leukemia: final 5-year results of the phase 2 PACE trial
Cortes, Jorge E., Kim, Dong-Wook, Pinilla-Ibarz, Javier, le Coutre, Philipp D., Paquette, Ronald, Chuah, Charles, Nicolini, Franck E., Apperley, Jane F., Khoury, H. Jean, Talpaz, Moshe, DeAngelo, Daniel J., Abruzzese, Elisabetta, Rea, Delphine, Baccarani, Michele, Müller, Martin C., Gambacorti-Passerini, Carlo, Lustgarten, Stephanie, Rivera, Victor M., Haluska, Frank G., Guilhot, François, Deininger, Michael W., Hochhaus, Andreas, Hughes, Timothy P., Shah, Neil P., Kantarjian, Hagop M.
Published in Blood (26.07.2018)
Published in Blood (26.07.2018)
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Enasidenib in mutant IDH2 relapsed or refractory acute myeloid leukemia
Stein, Eytan M., DiNardo, Courtney D., Pollyea, Daniel A., Fathi, Amir T., Roboz, Gail J., Altman, Jessica K., Stone, Richard M., DeAngelo, Daniel J., Levine, Ross L., Flinn, Ian W., Kantarjian, Hagop M., Collins, Robert, Patel, Manish R., Frankel, Arthur E., Stein, Anthony, Sekeres, Mikkael A., Swords, Ronan T., Medeiros, Bruno C., Willekens, Christophe, Vyas, Paresh, Tosolini, Alessandra, Xu, Qiang, Knight, Robert D., Yen, Katharine E., Agresta, Sam, de Botton, Stephane, Tallman, Martin S.
Published in Blood (10.08.2017)
Published in Blood (10.08.2017)
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Acute myeloid leukemia ontogeny is defined by distinct somatic mutations
Lindsley, R. Coleman, Mar, Brenton G., Mazzola, Emanuele, Grauman, Peter V., Shareef, Sarah, Allen, Steven L., Pigneux, Arnaud, Wetzler, Meir, Stuart, Robert K., Erba, Harry P., Damon, Lloyd E., Powell, Bayard L., Lindeman, Neal, Steensma, David P., Wadleigh, Martha, DeAngelo, Daniel J., Neuberg, Donna, Stone, Richard M., Ebert, Benjamin L.
Published in Blood (26.02.2015)
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Reconstructing the Lineage Histories and Differentiation Trajectories of Individual Cancer Cells in Myeloproliferative Neoplasms
Van Egeren, Debra, Escabi, Javier, Nguyen, Maximilian, Liu, Shichen, Reilly, Christopher R., Patel, Sachin, Kamaz, Baransel, Kalyva, Maria, DeAngelo, Daniel J., Galinsky, Ilene, Wadleigh, Martha, Winer, Eric S., Luskin, Marlise R., Stone, Richard M., Garcia, Jacqueline S., Hobbs, Gabriela S., Camargo, Fernando D., Michor, Franziska, Mullally, Ann, Cortes-Ciriano, Isidro, Hormoz, Sahand
Published in Cell stem cell (04.03.2021)
Published in Cell stem cell (04.03.2021)
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Increased neutrophil extracellular trap formation promotes thrombosis in myeloproliferative neoplasms
Wolach, Ofir, Sellar, Rob S, Martinod, Kimberly, Cherpokova, Deya, McConkey, Marie, Chappell, Ryan J, Silver, Alexander J, Adams, Dylan, Castellano, Cecilia A, Schneider, Rebekka K, Padera, Robert F, DeAngelo, Daniel J, Wadleigh, Martha, Steensma, David P, Galinsky, Ilene, Stone, Richard M, Genovese, Giulio, McCarroll, Steven A, Iliadou, Bozenna, Hultman, Christina, Neuberg, Donna, Mullally, Ann, Wagner, Denisa D, Ebert, Benjamin L
Published in Science translational medicine (11.04.2018)
Published in Science translational medicine (11.04.2018)
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Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia
Pan, Rongqing, Hogdal, Leah J, Benito, Juliana M, Bucci, Donna, Han, Lina, Borthakur, Gautam, Cortes, Jorge, DeAngelo, Daniel J, Debose, Lakeisha, Mu, Hong, Döhner, Hartmut, Gaidzik, Verena I, Galinsky, Ilene, Golfman, Leonard S, Haferlach, Torsten, Harutyunyan, Karine G, Hu, Jianhua, Leverson, Joel D, Marcucci, Guido, Müschen, Markus, Newman, Rachel, Park, Eugene, Ruvolo, Peter P, Ruvolo, Vivian, Ryan, Jeremy, Schindela, Sonja, Zweidler-McKay, Patrick, Stone, Richard M, Kantarjian, Hagop, Andreeff, Michael, Konopleva, Marina, Letai, Anthony G
Published in Cancer discovery (01.03.2014)
Published in Cancer discovery (01.03.2014)
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Phase IIB Trial of Oral Midostaurin (PKC412), the FMS-Like Tyrosine Kinase 3 Receptor (FLT3) and Multi-Targeted Kinase Inhibitor, in Patients With Acute Myeloid Leukemia and High-Risk Myelodysplastic Syndrome With Either Wild-Type or Mutated FLT3
FISCHER, Thomas, STONE, Richard M, KLIMEK, Virginia M, NIMER, Stephen D, GILLILAND, D. Gary, DUTREIX, Catherine, HUNTSMAN-LABED, Alice, VIRKUS, Jodi, GILES, Francis J, DEANGELO, Daniel J, GALINSKY, Ilene, ESTEY, Elihu, LANZA, Carlo, FOX, Edward, EHNINGER, Gerhard, FELDMAN, Eric J, SCHILLER, Gary J
Published in Journal of clinical oncology (01.10.2010)
Published in Journal of clinical oncology (01.10.2010)
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AZD1208, a potent and selective pan-Pim kinase inhibitor, demonstrates efficacy in preclinical models of acute myeloid leukemia
Keeton, Erika K., McEachern, Kristen, Dillman, Keith S., Palakurthi, Sangeetha, Cao, Yichen, Grondine, Michael R., Kaur, Surinder, Wang, Suping, Chen, Yuching, Wu, Allan, Shen, Minhui, Gibbons, Francis D., Lamb, Michelle L., Zheng, Xiaolan, Stone, Richard M., DeAngelo, Daniel J., Platanias, Leonidas C., Dakin, Les A., Chen, Huawei, Lyne, Paul D., Huszar, Dennis
Published in Blood (06.02.2014)
Published in Blood (06.02.2014)
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Use, variability, and justification of eligibility criteria for phase II and III clinical trials in acute leukemia
Hantel, Andrew, Luskin, Marlise R, Khan, Irum, Warner, Elizabeth, Patel, Anand A, Walsh, Thomas P, DeAngelo, Daniel J, Lathan, Christopher S, Abel, Gregory A
Published in Haematologica (Roma) (01.04.2024)
Published in Haematologica (Roma) (01.04.2024)
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The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia
Fenouille, Nina, Bassil, Christopher F, Ben-Sahra, Issam, Benajiba, Lina, Alexe, Gabriela, Ramos, Azucena, Pikman, Yana, Conway, Amy S, Burgess, Michael R, Li, Qing, Luciano, Frédéric, Auberger, Patrick, Galinsky, Ilene, DeAngelo, Daniel J, Stone, Richard M, Zhang, Yi, Perkins, Archibald S, Shannon, Kevin, Hemann, Michael T, Puissant, Alexandre, Stegmaier, Kimberly
Published in Nature medicine (01.03.2017)
Published in Nature medicine (01.03.2017)
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SYK Is a Critical Regulator of FLT3 in Acute Myeloid Leukemia
Puissant, Alexandre, Fenouille, Nina, Alexe, Gabriela, Pikman, Yana, Bassil, Christopher F., Mehta, Swapnil, Du, Jinyan, Kazi, Julhash U., Luciano, Frédéric, Rönnstrand, Lars, Kung, Andrew L., Aster, Jon C., Galinsky, Ilene, Stone, Richard M., DeAngelo, Daniel J., Hemann, Michael T., Stegmaier, Kimberly
Published in Cancer cell (10.02.2014)
Published in Cancer cell (10.02.2014)
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Exploiting an Asp-Glu "switch" in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia
Wagner, Florence F, Benajiba, Lina, Campbell, Arthur J, Weïwer, Michel, Sacher, Joshua R, Gale, Jennifer P, Ross, Linda, Puissant, Alexandre, Alexe, Gabriela, Conway, Amy, Back, Morgan, Pikman, Yana, Galinsky, Ilene, DeAngelo, Daniel J, Stone, Richard M, Kaya, Taner, Shi, Xi, Robers, Matthew B, Machleidt, Thomas, Wilkinson, Jennifer, Hermine, Olivier, Kung, Andrew, Stein, Adam J, Lakshminarasimhan, Damodharan, Hemann, Michael T, Scolnick, Edward, Zhang, Yan-Ling, Pan, Jen Q, Stegmaier, Kimberly, Holson, Edward B
Published in Science translational medicine (07.03.2018)
Published in Science translational medicine (07.03.2018)
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Management of adverse events associated with bosutinib treatment of chronic-phase chronic myeloid leukemia: expert panel review
Cortes, Jorge E, Apperley, Jane F, DeAngelo, Daniel J, Deininger, Michael W, Kota, Vamsi K, Rousselot, Philippe, Gambacorti-Passerini, Carlo
Published in Journal of hematology and oncology (27.12.2018)
Published in Journal of hematology and oncology (27.12.2018)
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A multicenter phase I/II study of obatoclax mesylate administered as a 3- or 24-hour infusion in older patients with previously untreated acute myeloid leukemia
Schimmer, Aaron D, Raza, Azra, Carter, Thomas H, Claxton, David, Erba, Harry, DeAngelo, Daniel J, Tallman, Martin S, Goard, Carolyn, Borthakur, Gautam
Published in PloS one (06.10.2014)
Published in PloS one (06.10.2014)
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Functional screening identifies CRLF2 in precursor B-cell acute lymphoblastic leukemia
Yoda, Akinori, Yoda, Yuka, Chiaretti, Sabina, Bar-Natan, Michal, Mani, Kartik, Rodig, Scott J, West, Nathan, Xiao, Yun, Brown, Jennifer R, Mitsiades, Constantine, Sattler, Martin, Kutok, Jeffrey L, DeAngelo, Daniel J, Wadleigh, Martha, Piciocchi, Alfonso, Dal Cin, Paola, Bradner, James E, Griffin, James D, Anderson, Kenneth C, Stone, Richard M, Ritz, Jerome, Foà, Robin, Aster, Jon C, Frank, David A, Weinstock, David M
Published in Proceedings of the National Academy of Sciences - PNAS (05.01.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (05.01.2010)
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MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia
Pikman, Yana, Lee, Benjamin H, Mercher, Thomas, McDowell, Elizabeth, Ebert, Benjamin L, Gozo, Maricel, Cuker, Adam, Wernig, Gerlinde, Moore, Sandra, Galinsky, Ilene, DeAngelo, Daniel J, Clark, Jennifer J, Lee, Stephanie J, Golub, Todd R, Wadleigh, Martha, Gilliland, D Gary, Levine, Ross L
Published in PLoS medicine (01.07.2006)
Published in PLoS medicine (01.07.2006)
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Interrogating the molecular genetics of chronic myeloproliferative malignancies for personalized management in 2021
Mughal, Tariq I, Psaila, Bethan, DeAngelo, Daniel J, Saglio, Giuseppe, Van Etten, Richard A, Radich, Jerald P
Published in Haematologica (Roma) (01.07.2021)
Published in Haematologica (Roma) (01.07.2021)
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