Differentiation of antiinflammatory and antitumorigenic properties of stabilized enantiomers of thalidomide analogs
Jacques, Vincent, Czarnik, Anthony W., Judge, Thomas M., Van der Ploeg, Lex H. T., DeWitt, Sheila H.
Published in Proceedings of the National Academy of Sciences - PNAS (24.03.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (24.03.2015)
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P1241: A NOVEL CEREBLON‐BINDING MOLECULAR GLUE, SP‐3164, SHOWS PRECLINICAL ACTIVITY IN NON‐HODGKIN LYMPHOMAS
Santiesteban, Daniela, Duncan, Aundrietta D., Mirza, Nadeem Q., Horrigan, Stephen, Dewitt, Sheila, Jacques, Vincent, Iyer, Swaminathan P.
Published in HemaSphere (08.08.2023)
Published in HemaSphere (08.08.2023)
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Deuterium‐Stabilized (R)‐Pioglitazone (PXL065) Is Responsible for Pioglitazone Efficacy in NASH yet Exhibits Little to No PPARγ Activity
Jacques, Vincent, Bolze, Sébastien, Hallakou‐Bozec, Sophie, Czarnik, Anthony W., Divakaruni, Ajit S., Fouqueray, Pascale, Murphy, Anne N., Van der Ploeg, Lex H.T., DeWitt, Sheila
Published in Hepatology communications (01.08.2021)
Published in Hepatology communications (01.08.2021)
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A solid phase approach to quinolones using the DIVERSOMER ® technology
MacDonald, Alasdair A, DeWitt, Sheila H, Hogan, Eleonora M, Ramage, Robert
Published in Tetrahedron letters (01.07.1996)
Published in Tetrahedron letters (01.07.1996)
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Evaluation of PXL065 – deuterium-stabilized (R)-pioglitazone in patients with NASH: A phase II randomized placebo-controlled trial (DESTINY-1)
Harrison, Stephen A., Thang, Carole, Bolze, Sébastien, Dewitt, Sheila, Hallakou-Bozec, Sophie, Dubourg, Julie, Bedossa, Pierre, Cusi, Kenneth, Ratziu, Vlad, Grouin, Jean-Marie, Moller, David E., Fouqueray, Pascale
Published in Journal of hepatology (01.05.2023)
Published in Journal of hepatology (01.05.2023)
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Therapeutic potential of deuterium‐stabilized (R)‐pioglitazone—PXL065—for X‐linked adrenoleukodystrophy
Monternier, Pierre‐Axel, Singh, Jaspreet, Parasar, Parveen, Theurey, Pierre, DeWitt, Sheila, Jacques, Vincent, Klett, Eric, Kaur, Navtej, Nagaraja, Tavarekere N., Moller, David E., Hallakou‐Bozec, Sophie
Published in Journal of inherited metabolic disease (01.07.2022)
Published in Journal of inherited metabolic disease (01.07.2022)
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중수소-농축 피오글리타존의 결정질 형태
GARDETTE EMELINE, BOLZE SEBASTIEN, NAVARRE LAURE FRANCOISE VALERIE, DEWITT SHEILA, JACQUES VINCENT
Year of Publication 03.05.2023
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Year of Publication 03.05.2023
Patent
Abstract 6253: SP-3164, a novel molecular glue degrader with activity in preclinical models of multiple myeloma
Duncan, Aundrietta D., Santiesteban, Daniela Y., Mirza, Nadeem Q., Horrigan, Steve, DeWitt, Sheila, Jacques, Vincent, Bergsagel, P. Leif
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Abstract 524: SP-3164, a novel ikaros and aiolos molecular glue degrader with preclinical activity in non-Hodgkin lymphomas
Santiesteban, Daniela Y., Duncan, Aundrietta D., Mirza, Nadeem Q., DeWitt, Sheila, Jacques, Vincent, Horrigan, Stephen, Iyer, Swaminathan P.
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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