A Facile Enantioselective Alkynylation of Chromones
DeRatt, Lindsey G., Pappoppula, Mukesh, Aponick, Aaron
Published in Angewandte Chemie International Edition (17.06.2019)
Published in Angewandte Chemie International Edition (17.06.2019)
Get full text
Journal Article
Synthesis of 4‑Alkylated Isocoumarins via Pd-Catalyzed α‑Arylation Reaction
Plunkett, Shane, DeRatt, Lindsey G, Kuduk, Scott D, Balsells, Jaume
Published in Organic letters (02.10.2020)
Published in Organic letters (02.10.2020)
Get full text
Journal Article
Tandem Amination/Oxetane Ring Opening toward Benzomorpholines
DeRatt, Lindsey G, Wang, Chao-Yuan, Kuduk, Scott D
Published in Journal of organic chemistry (03.12.2021)
Published in Journal of organic chemistry (03.12.2021)
Get full text
Journal Article
Mild Intramolecular Ring Opening of Oxetanes
DeRatt, Lindsey G, Lawson, Edward C, Wang, Chao-Yuan, Kuduk, Scott D
Published in Organic letters (06.12.2019)
Published in Organic letters (06.12.2019)
Get full text
Journal Article
Tandem Suzuki Coupling/Intramolecular Oxetane Ring Opening to Form Polycyclic Ring Systems
DeRatt, Lindsey G, Lawson, Edward C, Kumar, Kiran, Hwang, Soyon S, DesJarlais, Renee L, Kuduk, Scott D
Published in Organic letters (07.08.2020)
Published in Organic letters (07.08.2020)
Get full text
Journal Article
Discovery of JNJ-74856665: A Novel Isoquinolinone DHODH Inhibitor for the Treatment of AML
DeRatt, Lindsey G., Zhang, Zhuming, Pietsch, Christine, Cisar, Justin S., Zhang, Xiaochun, Wang, Weixue, Tanner, Alexandra, Matico, Rosalie, Shaffer, Paul, Jacoby, Edgar, Kazmi, Faraz, Shukla, Neetu, Bush, Tammy L., Patrick, Aaron, Philippar, Ulrike, Attar, Ricardo, Edwards, James P., Kuduk, Scott D.
Published in Journal of medicinal chemistry (11.07.2024)
Published in Journal of medicinal chemistry (11.07.2024)
Get full text
Journal Article
N‑Heterocyclic 3‑Pyridyl Carboxamide Inhibitors of DHODH for the Treatment of Acute Myelogenous Leukemia
Cisar, Justin S., Pietsch, Christine, DeRatt, Lindsey G., Jacoby, Edgar, Kazmi, Faraz, Keohane, Colleen, Legenski, Katie, Matico, Rosalie, Shaffer, Paul, Simonnet, Yvan, Tanner, Alexandra, Wang, Chao-Yuan, Wang, Weixue, Attar, Ricardo, Edwards, James P., Kuduk, Scott D.
Published in Journal of medicinal chemistry (25.08.2022)
Published in Journal of medicinal chemistry (25.08.2022)
Get full text
Journal Article
Di-fluoro azepane HBV capsid assembly modulators
DeRatt, Lindsey G., Stoops, Bart, Shaffer, Paul, Lam, Angela M., Espiritu, Christine, Vogel, Robert, Lau, Vincent, Flores, Osvaldo A., Kuduk, Scott D.
Published in Bioorganic & medicinal chemistry letters (15.08.2023)
Published in Bioorganic & medicinal chemistry letters (15.08.2023)
Get full text
Journal Article
Diazepinone HBV capsid assembly modulators
Kuduk, Scott D., DeRatt, Lindsey G., Stoops, Bart, Shaffer, Paul, Lam, Angela M., Espiritu, Christine, Vogel, Robert, Lau, Vincent, Flores, Osvaldo A., Hartman, George D.
Published in Bioorganic & medicinal chemistry letters (15.09.2022)
Published in Bioorganic & medicinal chemistry letters (15.09.2022)
Get full text
Journal Article
Identification of isoquinolinone DHODH inhibitor isosteres
DeRatt, Lindsey G., Zhang, Zhuming, Pietsch, E. Christine, Cisar, Justin, Wang, Aihua, Wang, Chao-yuan, Tanner, Alexandra, Shaffer, Paul, Jacoby, Edgar, Kazmi, Faraz, Shukla, Neetu, Philippar, Ulrike, Attar, Ricardo M., Edwards, James P., Kuduk, Scott D.
Published in Bioorganic & medicinal chemistry letters (15.11.2024)
Published in Bioorganic & medicinal chemistry letters (15.11.2024)
Get full text
Journal Article
A carboxylic acid isostere screen of the DHODH inhibitor Brequinar
DeRatt, Lindsey G., Christine Pietsch, E., Tanner, Alexandra, Shaffer, Paul, Jacoby, Edgar, Wang, Weixue, Kazmi, Faraz, Zhang, Xiaochun, Attar, Ricardo M., Edwards, James P., Kuduk, Scott D.
Published in Bioorganic & medicinal chemistry letters (15.11.2020)
Published in Bioorganic & medicinal chemistry letters (15.11.2020)
Get full text
Journal Article
Discovery of Alternative Binding Poses through Fragment-Based Identification of DHODH Inhibitors
DeRatt, Lindsey G., Pietsch, E. Christine, Cisar, Justin S., Jacoby, Edgar, Kazmi, Faraz, Matico, Rosalie, Shaffer, Paul, Tanner, Alexandra, Wang, Weixue, Attar, Ricardo, Edwards, James P., Kuduk, Scott D.
Published in ACS medicinal chemistry letters (14.03.2024)
Published in ACS medicinal chemistry letters (14.03.2024)
Get full text
Journal Article
FUSED HETEROCYCLIC DERIVATIVES AS ANTIVIRAL AGENTS
BURKE JOSEPH MICHAEL, WANG CHAO-YUAN, DERATT LINDSEY G, KUDUK SCOTT D
Year of Publication 14.01.2022
Get full text
Year of Publication 14.01.2022
Patent