Urinary galectin-3 binding protein (G3BP) as a biomarker for disease activity and renal pathology characteristics in lupus nephritis
Ding, Huihua, Shen, Yiwei, Lin, Cheng, Qin, Ling, He, Shijun, Dai, Min, Okitsu, Shinji L, DeMartino, Julie A, Guo, Qiang, Shen, Nan
Published in Arthritis research & therapy (28.03.2022)
Published in Arthritis research & therapy (28.03.2022)
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Assessment of Brd4 Inhibition in Idiopathic Pulmonary Fibrosis Lung Fibroblasts and in Vivo Models of Lung Fibrosis
Tang, Xiaoyan, Peng, Ruoqi, Phillips, Jonathan E, Deguzman, Jeremy, Ren, Yonglin, Apparsundaram, Subramanium, Luo, Qi, Bauer, Carla M, Fuentes, Maria E, DeMartino, Julie A, Tyagi, Gaurav, Garrido, Rosario, Hogaboam, Cory M, Denton, Christopher P, Holmes, Alan M, Kitson, Christopher, Stevenson, Christopher S, Budd, David C
Published in The American journal of pathology (01.08.2013)
Published in The American journal of pathology (01.08.2013)
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Targeting the SYK―BTK axis for the treatment of immunological and hematological disorders Recent progress and therapeutic perspectives
TAN, Seng-Lai, CHENG LIAO, LUCAS, Matthew C, STEVENSON, Christopher, DEMARTINO, Julie A
Published in Pharmacology & therapeutics (Oxford) (01.05.2013)
Published in Pharmacology & therapeutics (Oxford) (01.05.2013)
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RN486, a selective Bruton's tyrosine kinase inhibitor, abrogates immune hypersensitivity responses and arthritis in rodents
Xu, Daigen, Kim, Yong, Postelnek, Jennifer, Vu, Minh Diem, Hu, Dong-Qing, Liao, Cheng, Bradshaw, Mike, Hsu, Jonathan, Zhang, Jun, Pashine, Achal, Srinivasan, Dinesh, Woods, John, Levin, Anita, O'Mahony, Alison, Owens, Timothy D, Lou, Yan, Hill, Ronald J, Narula, Satwant, DeMartino, Julie, Fine, Jay S
Published in The Journal of pharmacology and experimental therapeutics (01.04.2012)
Published in The Journal of pharmacology and experimental therapeutics (01.04.2012)
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Discovery of N‑[Bis(4-methoxyphenyl)methyl]-4-hydroxy-2-(pyridazin-3-yl)pyrimidine-5-carboxamide (MK-8617), an Orally Active Pan-Inhibitor of Hypoxia-Inducible Factor Prolyl Hydroxylase 1–3 (HIF PHD1–3) for the Treatment of Anemia
Debenham, John S, Madsen-Duggan, Christina, Clements, Matthew J, Walsh, Thomas F, Kuethe, Jeffrey T, Reibarkh, Mikhail, Salowe, Scott P, Sonatore, Lisa M, Hajdu, Richard, Milligan, James A, Visco, Denise M, Zhou, Dan, Lingham, Russell B, Stickens, Dominique, DeMartino, Julie A, Tong, Xinchun, Wolff, Michael, Pang, Jianmei, Miller, Randy R, Sherer, Edward C, Hale, Jeffrey J
Published in Journal of medicinal chemistry (22.12.2016)
Published in Journal of medicinal chemistry (22.12.2016)
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Impaired Neuropathic Pain Responses in Mice Lacking the Chemokine Receptor CCR2
Abbadie, Catherine, Lindia, Jill A., Cumiskey, Anne Marie, Peterson, Larry B., Mudgett, John S., Bayne, Ellen K., DeMartino, Julie A., MacIntyre, D. Euan, Forrest, Michael J.
Published in Proceedings of the National Academy of Sciences - PNAS (24.06.2003)
Published in Proceedings of the National Academy of Sciences - PNAS (24.06.2003)
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BET bromodomain proteins mediate downstream signaling events following growth factor stimulation in human lung fibroblasts and are involved in bleomycin-induced pulmonary fibrosis
Tang, Xiaoyan, Peng, Ruoqi, Ren, Yonglin, Apparsundaram, Subramanium, Deguzman, Jeremy, Bauer, Carla M, Hoffman, Ann F, Hamilton, Shannon, Liang, Zhenmin, Zeng, Hang, Fuentes, Maria E, Demartino, Julie A, Kitson, Christopher, Stevenson, Christopher S, Budd, David C
Published in Molecular pharmacology (01.01.2013)
Published in Molecular pharmacology (01.01.2013)
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Autoantibody repertoire characterization provides insight into the pathogenesis of monogenic and polygenic autoimmune diseases
Clarke, Thomas, Du, Pan, Kumar, Satyendra, Okitsu, Shinji L, Schuette, Mark, An, Qi, Zhang, Jinyang, Tzvetkov, Evgeni, Jensen, Mark A, Niewold, Timothy B, Ferre, Elise M N, Nardone, Julie, Lionakis, Michail S, Vlach, Jaromir, DeMartino, Julie, Bender, Andrew T
Published in Frontiers in immunology (10.02.2023)
Published in Frontiers in immunology (10.02.2023)
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Bruton's Tyrosine Kinase mediates platelet receptor-induced generation of microparticles: A potential mechanism for amplification of inflammatory responses in rheumatoid arthritis synovial joints
Hsu, Jonathan, Gu, Yajuan, Tan, Seng-Lai, Narula, Satwant, DeMartino, Julie A, Liao, Cheng
Published in Immunology letters (01.02.2013)
Published in Immunology letters (01.02.2013)
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Characterization of a novel CRAC inhibitor that potently blocks human T cell activation and effector functions
Chen, Gang, Panicker, Sandip, Lau, Kai-Yeung, Apparsundaram, Subramaniam, Patel, Vaishali A., Chen, Shiow-Ling, Soto, Rothschild, Jung, Jimmy K.C., Ravindran, Palanikumar, Okuhara, Dayne, Bohnert, Gary, Che, Qinglin, Rao, Patricia E., Allard, John D., Badi, Laura, Bitter, Hans-Marcus, Nunn, Philip A., Narula, Satwant K., DeMartino, Julie A.
Published in Molecular immunology (01.07.2013)
Published in Molecular immunology (01.07.2013)
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1,3,8-Triazaspiro[4.5]decane-2,4-diones as Efficacious Pan-Inhibitors of Hypoxia-Inducible Factor Prolyl Hydroxylase 1–3 (HIF PHD1–3) for the Treatment of Anemia
Vachal, Petr, Miao, Shouwu, Pierce, Joan M, Guiadeen, Deodial, Colandrea, Vincent J, Wyvratt, Matthew J, Salowe, Scott P, Sonatore, Lisa M, Milligan, James A, Hajdu, Richard, Gollapudi, Anantha, Keohane, Carol A, Lingham, Russell B, Mandala, Suzanne M, DeMartino, Julie A, Tong, Xinchun, Wolff, Michael, Steinhuebel, Dietrich, Kieczykowski, Gerard R, Fleitz, Fred J, Chapman, Kevin, Athanasopoulos, John, Adam, Gregory, Akyuz, Can D, Jena, Dhirendra K, Lusen, Jeffrey W, Meng, Juncai, Stein, Benjamin D, Xia, Lei, Sherer, Edward C, Hale, Jeffrey J
Published in Journal of medicinal chemistry (12.04.2012)
Published in Journal of medicinal chemistry (12.04.2012)
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Evidence for cyclic diguanylate as a vaccine adjuvant with novel immunostimulatory activities
Gray, Peter M., Forrest, Gail, Wisniewski, Thomas, Porter, Gene, Freed, Daniel C., DeMartino, Julie A., Zaller, Dennis M., Guo, Zhiqiang, Leone, Joseph, Fu, Tong-Ming, Vora, Kalpit A.
Published in Cellular immunology (01.07.2012)
Published in Cellular immunology (01.07.2012)
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Identifying lupus Patient Subsets Through Immune Cell Deconvolution of Gene Expression Data in Two Atacicept Phase II Studies
Studham, Matthew, Vazquez‐Mateo, Cristina, Samy, Eileen, Haselmayer, Philipp, Aydemir, Aida, Rolfe, P. Alexander, Merrill, Joan T., Morand, Eric F., DeMartino, Julie, Kao, Amy, Townsend, Robert
Published in ACR open rheumatology (01.10.2023)
Published in ACR open rheumatology (01.10.2023)
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Photochemical preparation of a pyridone containing tetracycle: A Jak protein kinase inhibitor
THOMPSON, James E, CUBBON, Rose M, DEMARTINO, Julie A, CUMMINGS, Richard T, WICKER, Linda S, FRANKSHUN, Robert, CUNNINGHAM, Barry R, CAMERON, Patricia M, MEINKE, Peter T, LIVERTON, Nigel, YOUMIN WENG
Published in Bioorganic & medicinal chemistry letters (22.04.2002)
Published in Bioorganic & medicinal chemistry letters (22.04.2002)
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Potent 1,3,4-trisubstituted pyrrolidine CCR5 receptor antagonists: effects of fused heterocycles on antiviral activity and pharmacokinetic properties
Kim, Dooseop, Wang, Liping, Hale, Jeffrey J., Lynch, Christopher L., Budhu, Richard J., MacCoss, Malcolm, Mills, Sander G., Malkowitz, Lorraine, Gould, Sandra L., DeMartino, Julie A., Springer, Martin S., Hazuda, Daria, Miller, Michael, Kessler, Joseph, Hrin, Renee C., Carver, Gwen, Carella, Anthony, Henry, Karen, Lineberger, Janet, Schleif, William A., Emini, Emilio A.
Published in Bioorganic & medicinal chemistry letters (15.04.2005)
Published in Bioorganic & medicinal chemistry letters (15.04.2005)
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Natural regulatory T cells are resistant to calcium release-activated calcium (CRAC/ORAI) channel inhibition
Jin, Shu, Chin, Jayne, Kitson, Christopher, Woods, John, Majmudar, Rupal, Carvajal, Valerie, Allard, John, Demartino, Julie, Narula, Satwant, Thomas-Karyat, Dori A
Published in International immunology (01.09.2013)
Published in International immunology (01.09.2013)
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Inhibition of IRF5 cellular activity with cell-penetrating peptides that target homodimerization
Banga, Jaspreet, Srinivasan, Dinesh, Sun, Chia-Chi, Thompson, Cherrie D, Milletti, Francesca, Huang, Kuo-Sen, Hamilton, Shannon, Song, Su, Hoffman, Ann F, Qin, Yajuan Gu, Matta, Bharati, LaPan, Margaret, Guo, Qin, Lu, Gang, Li, Dan, Qian, Hong, Bolin, David R, Liang, Lena, Wartchow, Charles, Qiu, Jin, Downing, Michelle, Narula, Satwant, Fotouhi, Nader, DeMartino, Julie A, Tan, Seng-Lai, Chen, Gang, Barnes, Betsy J
Published in Science advances (01.05.2020)
Published in Science advances (01.05.2020)
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CCR5 Blockade Modulates Inflammation and Alloimmunity in Primates
Schroder, Carsten, Pierson, Richard N., III, Nguyen, Bao-Ngoc H, Kawka, Douglas W, Peterson, Laurence B, Wu, Guosheng, Zhang, Tianshu, Springer, Martin S, Siciliano, Sal J, Iliff, Susan, Ayala, Julia M, Lu, Min, Mudgett, John S, Lyons, Kathy, Mills, Sander G, Miller, Geraldine G, Singer, Irwin I, Azimzadeh, Agnes M, DeMartino, Julie A
Published in Journal of Immunology (15.08.2007)
Published in Journal of Immunology (15.08.2007)
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Antibody-mediated blockade of the CXCR3 chemokine receptor results in diminished recruitment of T helper 1 cells into sites of inflammation
Xie, Jenny H., Nomura, Naomi, Lu, Min, Chen, Shiow‐Ling, Koch, Greg E., Weng, Youmin, Rosa, Raymond, Di Salvo, Jerry, Mudgett, John, Peterson, Laurence B., Wicker, Linda S., DeMartino, Julie A.
Published in Journal of leukocyte biology (01.06.2003)
Published in Journal of leukocyte biology (01.06.2003)
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Use of a small molecule CCR5 inhibitor in macaques to treat simian immunodeficiency virus infection or prevent simian-human immunodeficiency virus infection
Veazey, Ronald S, Klasse, Per Johan, Ketas, Thomas J, Reeves, Jacqueline D, Piatak, Jr, Michael, Kunstman, Kevin, Kuhmann, Shawn E, Marx, Preston A, Lifson, Jeffrey D, Dufour, Jason, Mefford, Megan, Pandrea, Ivona, Wolinsky, Steven M, Doms, Robert W, DeMartino, Julie A, Siciliano, Salvatore J, Lyons, Kathy, Springer, Martin S, Moore, John P
Published in The Journal of experimental medicine (17.11.2003)
Published in The Journal of experimental medicine (17.11.2003)
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