Specific Notch receptor-ligand interactions control human TCR-αβ/γδ development by inducing differential Notch signal strength
Van de Walle, Inge, Waegemans, Els, De Medts, Jelle, De Smet, Greet, De Smedt, Magda, Snauwaert, Sylvia, Vandekerckhove, Bart, Kerre, Tessa, Leclercq, Georges, Plum, Jean, Gridley, Thomas, Wang, Tao, Koch, Ute, Radtke, Freddy, Taghon, Tom
Published in The Journal of experimental medicine (08.04.2013)
Published in The Journal of experimental medicine (08.04.2013)
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Journal Article
GATA3 induces human T-cell commitment by restraining Notch activity and repressing NK-cell fate
Van de Walle, Inge, Dolens, Anne-Catherine, Durinck, Kaat, De Mulder, Katrien, Van Loocke, Wouter, Damle, Sagar, Waegemans, Els, De Medts, Jelle, Velghe, Imke, De Smedt, Magda, Vandekerckhove, Bart, Kerre, Tessa, Plum, Jean, Leclercq, Georges, Rothenberg, Ellen V., Van Vlierberghe, Pieter, Speleman, Frank, Taghon, Tom
Published in Nature communications (06.04.2016)
Published in Nature communications (06.04.2016)
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Journal Article
Jagged2 acts as a Delta-like Notch ligand during early hematopoietic cell fate decisions
Van de Walle, Inge, De Smet, Greet, Gärtner, Martina, De Smedt, Magda, Waegemans, Els, Vandekerckhove, Bart, Leclercq, Georges, Plum, Jean, Aster, Jon C., Bernstein, Irwin D., Guidos, Cynthia J., Kyewski, Bruno, Taghon, Tom
Published in Blood (28.04.2011)
Published in Blood (28.04.2011)
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Functionally Mature CD4 and CD8 TCRαβ Cells Are Generated in OP9-DL1 Cultures from Human CD34+ Hematopoietic Cells
Van Coppernolle, Stefanie, Verstichel, Greet, Timmermans, Frank, Velghe, Imke, Vermijlen, David, De Smedt, Magda, Leclercq, Georges, Plum, Jean, Taghon, Tom, Vandekerckhove, Bart, Kerre, Tessa
Published in The Journal of immunology (1950) (15.10.2009)
Published in The Journal of immunology (1950) (15.10.2009)
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Journal Article
Both CD34+38+ and CD34+38- Cells Home Specifically to the Bone Marrow of NOD/LtSZ scid/scid Mice but Show Different Kinetics in Expansion
Kerre, Tessa C. C, De Smet, Greet, De Smedt, Magda, Offner, Fritz, De Bosscher, Jose, Plum, Jean, Vandekerckhove, Bart
Published in The Journal of immunology (1950) (01.10.2001)
Published in The Journal of immunology (1950) (01.10.2001)
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Journal Article
HOX-A10 regulates hematopoietic lineage commitment: evidence for a monocyte-specific transcription factor
Taghon, Tom, Stolz, Frank, De Smedt, Magda, Cnockaert, Maggy, Verhasselt, Bruno, Plum, Jean, Leclercq, Georges
Published in Blood (15.02.2002)
Published in Blood (15.02.2002)
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Journal Article
Enforced Expression of GATA-3 Severely Reduces Human Thymic Cellularity
Taghon, Tom, De Smedt, Magda, Stolz, Frank, Cnockaert, Maggy, Plum, Jean, Leclercq, Georges
Published in The Journal of immunology (1950) (15.10.2001)
Published in The Journal of immunology (1950) (15.10.2001)
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T-lymphoid differentiation potential measured in vitro is higher in CD34+CD38−/lo hematopoietic stem cells from umbilical cord blood than from bone marrow and is an intrinsic property of the cells
DE SMEDT, Magda, LECLERCQ, Georges, VANDEKERCKHOVE, Bart, KERRE, Tessa, TAGHON, Tom, PLUM, Jean
Published in Haematologica (Roma) (01.05.2011)
Published in Haematologica (Roma) (01.05.2011)
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Endothelial Outgrowth Cells Are Not Derived From CD133+ Cells or CD45+ Hematopoietic Precursors
Timmermans, Frank, Van Hauwermeiren, Filip, De Smedt, Magda, Raedt, Robrecht, Plasschaert, Frank, De Buyzere, Marc L, Gillebert, Thierry C, Plum, Jean, Vandekerckhove, Bart
Published in Arteriosclerosis, thrombosis, and vascular biology (01.07.2007)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.07.2007)
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Journal Article
Specific Notch receptor-ligand interactions control human TCR- alpha beta / gamma delta development by inducing differential Notch signal strength
Van de Walle, Inge, Waegemans, Els, De Medts, Jelle, De Smet, Greet, De Smedt, Magda, Snauwaert, Sylvia, Vandekerckhove, Bart, Kerre, Tessa, Leclercq, Georges, Plum, Jean, Gridley, Thomas, Wang, Tao, Koch, Ute, Radtke, Freddy, Taghon, Tom
Published in The Journal of experimental medicine (08.04.2013)
Published in The Journal of experimental medicine (08.04.2013)
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Journal Article
Generation of T Cells from Human Embryonic Stem Cell-Derived Hematopoietic Zones
Timmermans, Frank, Velghe, Imke, Vanwalleghem, Lieve, De Smedt, Magda, Van Coppernolle, Stefanie, Taghon, Tom, Moore, Harry D, Leclercq, Georges, Langerak, Anton W, Kerre, Tessa, Plum, Jean, Vandekerckhove, Bart
Published in The Journal of immunology (1950) (01.06.2009)
Published in The Journal of immunology (1950) (01.06.2009)
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Journal Article
An early decrease in Notch activation is required for human TCR-αβ lineage differentiation at the expense of TCR-γδ T cells
Van de Walle, Inge, De Smet, Greet, De Smedt, Magda, Vandekerckhove, Bart, Leclercq, Georges, Plum, Jean, Taghon, Tom
Published in Blood (26.03.2009)
Published in Blood (26.03.2009)
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Journal Article
Notch3 activation is sufficient but not required for inducing human T-lineage specification
Waegemans, Els, Van de Walle, Inge, De Medts, Jelle, De Smedt, Magda, Kerre, Tessa, Vandekerckhove, Bart, Leclercq, Georges, Wang, Tao, Plum, Jean, Taghon, Tom
Published in The Journal of immunology (1950) (15.12.2014)
Published in The Journal of immunology (1950) (15.12.2014)
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Journal Article
Notch signaling is required for proliferation but not for differentiation at a well-defined β-selection checkpoint during human T-cell development
Taghon, Tom, Van de Walle, Inge, De Smet, Greet, De Smedt, Magda, Leclercq, Georges, Vandekerckhove, Bart, Plum, Jean
Published in Blood (02.04.2009)
Published in Blood (02.04.2009)
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Journal Article
Notch signaling induces cytoplasmic CD3ϵ expression in human differentiating NK cells
De Smedt, Magda, Taghon, Tom, Van de Walle, Inge, De Smet, Greet, Leclercq, Georges, Plum, Jean
Published in Blood (01.10.2007)
Published in Blood (01.10.2007)
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Journal Article
Thymic Repopulation by CD34+ Human Cord Blood Cells After Expansion in Stroma-Free Culture
Verhasselt, Bruno, Kerre, Tessa, Naessens, Evelien, Vanhecke, Dominique, De Smedt, Magda, Vandekerckhove, Bart, Plum, Jean
Published in Blood (01.12.1999)
Published in Blood (01.12.1999)
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Journal Article
CD27-deficient mice show normal NK-cell differentiation but impaired function upon stimulation
De Colvenaer, Veerle, Taveirne, Sylvie, Delforche, Maarten, De Smedt, Magda, Vandekerckhove, Bart, Taghon, Tom, Boon, Louis, Plum, Jean, Leclercq, Georges
Published in Immunology and cell biology (01.10.2011)
Published in Immunology and cell biology (01.10.2011)
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Journal Article
Continuous CD27 triggering in vivo strongly reduces NK cell numbers
De Colvenaer, Veerle, Taveirne, Sylvie, Hamann, Jörg, de Bruin, Alex M, De Smedt, Magda, Taghon, Tom, Vandekerckhove, Bart, Plum, Jean, van Lier, Rene, Leclercq, Georges
Published in European journal of immunology (01.04.2010)
Published in European journal of immunology (01.04.2010)
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