Navigating tissue chips from development to dissemination: A pharmaceutical industry perspective
Ewart, Lorna, Fabre, Kristin, Chakilam, Ananthsrinivas, Dragan, Yvonne, Duignan, David B, Eswaraka, Jeetu, Gan, Jinping, Guzzie-Peck, Peggy, Otieno, Monicah, Jeong, Claire G, Keller, Douglas A, de Morais, Sonia M, Phillips, Jonathan A, Proctor, William, Sura, Radhakrishna, Van Vleet, Terry, Watson, David, Will, Yvonne, Tagle, Danilo, Berridge, Brian
Published in Experimental biology and medicine (Maywood, N.J.) (01.10.2017)
Published in Experimental biology and medicine (Maywood, N.J.) (01.10.2017)
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A High Throughput, 384-Well, Semi-Automated, Hepatocyte Intrinsic Clearance Assay for Screening New Molecular Entities in Drug Discovery
Heinle, Lance, Peterkin, Vincent, de Morais, Sonia M, Jenkins, Gary J, Badagnani, Ilaria
Published in Combinatorial chemistry & high throughput screening (01.01.2015)
Published in Combinatorial chemistry & high throughput screening (01.01.2015)
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In Vitro P-glycoprotein Assays to Predict the in Vivo Interactions of P-glycoprotein with Drugs in the Central Nervous System
BO FENG, MILLS, Jessica B, DAVIDSON, Ralph E, MIRELES, Rouchelle J, JANISZEWSKI, John S, TROUTMAN, Matthew D, DE MORAIS, Sonia M
Published in Drug metabolism and disposition (01.02.2008)
Published in Drug metabolism and disposition (01.02.2008)
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Quantitation of Plasma Membrane Drug Transporters in Kidney Tissue and Cell Lines Using a Novel Proteomic Approach Enabled a Prospective Prediction of Metformin Disposition
Kikuchi, Ryota, Chiou, William J, Durbin, Kenneth R, Savaryn, John P, Ma, Junli, Emami Riedmaier, Arian, de Morais, Sonia M, Jenkins, Gary J, Bow, Daniel A J
Published in Drug metabolism and disposition (01.10.2021)
Published in Drug metabolism and disposition (01.10.2021)
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Use of Immortalized Human Hepatocytes to Predict the Magnitude of Clinical Drug-Drug Interactions Caused by CYP3A4 Induction
RIPP, Sharon L, MILLS, Jessica B, FAHMI, Odette A, TREVENA, Kristen A, LIRAS, Jennifer L, MAURER, Tristan S, DE MORAIS, Sonia M
Published in Drug metabolism and disposition (01.10.2006)
Published in Drug metabolism and disposition (01.10.2006)
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Utility of a Novel Oatp1b2 Knockout Mouse Model for Evaluating the Role of Oatp1b2 in the Hepatic Uptake of Model Compounds
CUIPING CHEN, STOCK, Jeffery L, XINGRONG LIU, JILIN SHI, VAN DEUSEN, Jeffrey W, DIMATTIA, Debra A, DULLEA, Robert G, DE MORALS, Sonia M
Published in Drug metabolism and disposition (01.09.2008)
Published in Drug metabolism and disposition (01.09.2008)
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Metabolism and Disposition of a Novel B-Cell Lymphoma-2 Inhibitor Venetoclax in Humans and Characterization of Its Unusual Metabolites
Liu, Hong, Michmerhuizen, Melissa J, Lao, Yanbin, Wan, Katty, Salem, Ahmed Hamed, Sawicki, James, Serby, Michael, Vaidyanathan, Srirajan, Wong, Shekman L, Agarwal, Suresh, Dunbar, Martin, Sydor, Jens, de Morais, Sonia M, Lee, Anthony J
Published in Drug metabolism and disposition (01.03.2017)
Published in Drug metabolism and disposition (01.03.2017)
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Mechanisms and Predictions of Drug-Drug Interactions of the Hepatitis C Virus Three Direct-Acting Antiviral Regimen: Paritaprevir/Ritonavir, Ombitasvir, and Dasabuvir
Shebley, Mohamad, Liu, Jinrong, Kavetskaia, Olga, Sydor, Jens, de Morais, Sonia M, Fischer, Volker, Nijsen, Marjoleen J M A, Bow, Daniel A J
Published in Drug metabolism and disposition (01.07.2017)
Published in Drug metabolism and disposition (01.07.2017)
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Comparative gene expression profiles of ABC transporters in brain microvessel endothelial cells and brain in five species including human
Warren, Mark S., Zerangue, Noa, Woodford, Katie, Roberts, Lori M., Tate, Emily H., Feng, Bo, Li, Cheryl, Feuerstein, Thomas J., Gibbs, John, Smith, Bill, de Morais, Sonia M., Dower, William J., Koller, Kerry J.
Published in Pharmacological research (01.06.2009)
Published in Pharmacological research (01.06.2009)
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Prediction of Clinical Drug–Drug Interactions of Veliparib (ABT-888) with Human Renal Transporters (OAT1, OAT3, OCT2, MATE1, and MATE2K)
Kikuchi, Ryota, Lao, Yanbin, Bow, Daniel A.J., Chiou, William J., Andracki, Mark E., Carr, Robert A., Voorman, Richard L., De Morais, Sonia M.
Published in Journal of pharmaceutical sciences (01.12.2013)
Published in Journal of pharmaceutical sciences (01.12.2013)
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Metabolism and transporter-mediated drug–drug interactions of the endothelin-A receptor antagonist CI-1034
Sahi, Jasminder, Sinz, Michael W., Campbell, Scott, Mireles, Rouchelle, Zheng, Xianxian, Rose, Kelly A., Raeissi, Shamsi, Hashim, Muhammed F., Ye, Yuyang, de Morais, Sonia M., Black, Christopher, Tugnait, Meera, Keller, Laurence H.
Published in Chemico-biological interactions (01.02.2006)
Published in Chemico-biological interactions (01.02.2006)
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Metabolism and Disposition of Pan-Genotypic Inhibitor of Hepatitis C Virus NS5A Ombitasvir in Humans
Shen, Jianwei, Serby, Michael, Surber, Bruce, Lee, Anthony J, Ma, Junli, Badri, Prajakta, Menon, Rajeev, Kavetskaia, Olga, de Morais, Sonia M, Sydor, Jens, Fischer, Volker
Published in Drug metabolism and disposition (01.08.2016)
Published in Drug metabolism and disposition (01.08.2016)
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