Discovery and gram-scale synthesis of BMS-593214, a potent, selective FVIIa inhibitor
Priestley, E. Scott, De Lucca, Indawati, Zhou, Jinglan, Zhou, Jiacheng, Saiah, Eddine, Stanton, Robert, Robinson, Leslie, Luettgen, Joseph M., Wei, Anzhi, Wen, Xiao, Knabb, Robert M., Wong, Pancras C., Wexler, Ruth R.
Published in Bioorganic & medicinal chemistry letters (15.04.2013)
Published in Bioorganic & medicinal chemistry letters (15.04.2013)
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Journal Article
Discovery of Milvexian, a High-Affinity, Orally Bioavailable Inhibitor of Factor XIa in Clinical Studies for Antithrombotic Therapy
Dilger, Andrew K, Pabbisetty, Kumar B, Corte, James R, De Lucca, Indawati, Fang, Tianan, Yang, Wu, Pinto, Donald J. P, Wang, Yufeng, Zhu, Yeheng, Mathur, Arvind, Li, Jianqing, Hou, Xiaoping, Smith, Daniel, Sun, Dawn, Zhang, Huiping, Krishnananthan, Subramaniam, Wu, Dauh-Rurng, Myers, Joseph E, Sheriff, Steven, Rossi, Karen A, Chacko, Silvi, Zheng, Joanna J, Galella, Michael A, Ziemba, Theresa, Dierks, Elizabeth A, Bozarth, Jeffrey M, Wu, Yiming, Crain, Earl, Wong, Pancras C, Luettgen, Joseph M, Wexler, Ruth R, Ewing, William R
Published in Journal of medicinal chemistry (10.02.2022)
Published in Journal of medicinal chemistry (10.02.2022)
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Journal Article
Selection of a Thiazole Urea-Resistant Variant of Bovine Viral Diarrhoea Virus That Maps to the RNA-Dependent RNA Polymerase
King, Robert W, Scarnati, Helen T, Priestley, E Scott, De Lucca, Indawati, Bansal, Anu, Williams, J Kendall
Published in Antiviral chemistry & chemotherapy (01.10.2002)
Published in Antiviral chemistry & chemotherapy (01.10.2002)
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Journal Article
Structure based design of macrocyclic factor XIa inhibitors: Discovery of cyclic P1 linker moieties with improved oral bioavailability
Clark, Charles G., Rossi, Karen A., Corte, James R., Fang, Tianan, Smallheer, Joanne M., De Lucca, Indawati, Nirschl, David S., Orwat, Michael J., Pinto, Donald J.P., Hu, Zilun, Wang, Yufeng, Yang, Wu, Jeon, Yoon, Ewing, William R., Myers, Joseph E., Sheriff, Steven, Lou, Zhen, Bozarth, Jeffrey M., Wu, Yiming, Rendina, Alan, Harper, Timothy, Zheng, Joanna, Xin, Baomin, Xiang, Qian, Luettgen, Joseph M., Seiffert, Dietmar A., Wexler, Ruth R., Lam, Patrick Y.S.
Published in Bioorganic & medicinal chemistry letters (01.10.2019)
Published in Bioorganic & medicinal chemistry letters (01.10.2019)
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Journal Article
P1 Phenethyl peptide boronic acid inhibitors of HCV NS3 protease
Priestley, E.Scott, De Lucca, Indawati, Ghavimi, Bahman, Erickson-Viitanen, Susan, Decicco, Carl P.
Published in Bioorganic & medicinal chemistry letters (04.11.2002)
Published in Bioorganic & medicinal chemistry letters (04.11.2002)
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Journal Article
5-membered and bicyclic heterocyclic amides as inhibitors of ROCK
Thiyagarajan, Kamalraj, Glunz, Peter W, Ladziata, Vladimir, Maishal, Tarun Kumar, De Lucca, Indawati, Tangirala, Raghuram, Tora, George O
Year of Publication 13.06.2023
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Year of Publication 13.06.2023
Patent
5-MEMBERED AND BICYCLIC HETEROCYCLIC AMIDES AS INHIBITORS OF ROCK
Thiyagarajan, Kamalraj, Glunz, Peter W, Ladziata, Vladimir, Maishal, Tarun Kumar, De Lucca, Indawati, Tangirala, Raghuram, Tora, George O
Year of Publication 10.11.2022
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Year of Publication 10.11.2022
Patent
Pyrimidinones as factor xia inhibitors
Ewing, William R, Wang, Yufeng, Fang, Tianan, Pinto, Donald J.p, Pabbisetty, Kumar Balashanmuga, Corte, James R, Yang, Wu, Orwat, Michael J, Dilger, Andrew K, De Lucca, Indawati, Wexler, Ruth R, Smith Ii, Leon M, Zhu, Yeheng
Year of Publication 26.01.2024
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Year of Publication 26.01.2024
Patent
Pyrimidinones as factor xia inhibitors
Ewing, William R, Wang, Yufeng, Fang, Tianan, Pinto, Donald J.p, Pabbisetty, Kumar Balashanmuga, Corte, James R, Yang, Wu, Orwat, Michael J, Dilger, Andrew K, De Lucca, Indawati, Wexler, Ruth R, Smith Ii, Leon M, Zhu, Yeheng
Year of Publication 26.01.2024
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Year of Publication 26.01.2024
Patent
Pyrimidinones as factor XIa inhibitors
Ewing, William R, Wang, Yufeng, Fang, Tianan, Pabbisetty, Kumar Balashanmuga, Corte, James R, Yang, Wu, Orwat, Michael J, Dilger, Andrew K, Smith II, Leon M, De Lucca, Indawati, Wexler, Ruth R, Pinto, Donald J.P, Zhu, Yeheng
Year of Publication 23.11.2023
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Year of Publication 23.11.2023
Patent
MACROCYCLES WITH HETROCYCLIC P2' GROUPS AS FACTOR XIA INHIBITORS
Ewing, William R, Wang, Yufeng, Pinto, Donald J. P, Fang, Tianan, Pabbisetty, Kumar Balashanmuga, Corte, James R, Yang, Wu, Orwat, Michael J, Dilger, Andrew K, Smith II, Leon M, De Lucca, Indawati, Wexler, Ruth R, Zhu, Yeheng
Year of Publication 06.07.2023
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Year of Publication 06.07.2023
Patent
5-membered and bicyclic heterocyclic amides as inhibitors of rock
Thiyagarajan, Kamalraj, Glunz, Peter W, Ladziata, Vladimir, Maishal, Tarun Kumar, De Lucca, Indawati, Tangirala, Raghuram, Tora, George O
Year of Publication 03.08.2021
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Year of Publication 03.08.2021
Patent
Macrocycles with hetrocyclic p2' groups as factor xia inhibitors
Ewing, William R, Wang, Yufeng, Fang, Tianan, Pinto, Donald J.p, Pabbisetty, Kumar Balashanmuga, Corte, James R, Yang, Wu, Orwat, Michael J, Dilger, Andrew K, De Lucca, Indawati, Wexler, Ruth R, Smith, Leon M. Ii, Zhu, Yeheng
Year of Publication 28.04.2023
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Year of Publication 28.04.2023
Patent
Macrocycles with hetrocyclic p2' groups as factor xia inhibitors
Ewing, William R, Wang, Yufeng, Fang, Tianan, Pinto, Donald J.p, Pabbisetty, Kumar Balashanmuga, Corte, James R, Yang, Wu, Orwat, Michael J, Dilger, Andrew K, De Lucca, Indawati, Wexler, Ruth R, Smith, Leon M. Ii, Zhu, Yeheng
Year of Publication 31.03.2023
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Year of Publication 31.03.2023
Patent
MACROCYCLES WITH HETROCYCLIC P2' GROUPS AS FACTOR XIA INHIBITORS
Ewing, William R, Wang, Yufeng, Pinto, Donald J. P, Fang, Tianan, Pabbisetty, Kumar Balashanmuga, Corte, James R, Yang, Wu, Orwat, Michael J, Dilger, Andrew K, Smith II, Leon M, De Lucca, Indawati, Wexler, Ruth R, Zhu, Yeheng
Year of Publication 30.03.2023
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Year of Publication 30.03.2023
Patent
5-MEMBERED AND BICYCLIC HETEROCYCLIC AMIDES AS INHIBITORS OF ROCK
Thiyagarajan, Kamalraj, Glunz, Peter W, Ladziata, Vladimir, Maishal, Tarun Kumar, De Lucca, Indawati, Tangirala, Raghuram, Tora, George O
Year of Publication 20.05.2021
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Year of Publication 20.05.2021
Patent
PYRIMIDINONES AS FACTOR XIA INHIBITORS
Ewing, William R, Wang, Yufeng, Fang, Tianan, Pabbisetty, Kumar Balashanmuga, Smith, II, Leon M, Corte, James R, Yang, Wu, Orwat, Michael J, Dilger, Andrew K, De Lucca, Indawati, Wexler, Ruth R, Pinto, Donald J.P, Zhu, Yeheng
Year of Publication 10.02.2022
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Year of Publication 10.02.2022
Patent
Pyrimidinones as factor XIa inhibitors
Ewing, William R, Wang, Yufeng, Fang, Tianan, Pabbisetty, Kumar Balashanmuga, Corte, James R, Yang, Wu, Orwat, Michael J, Dilger, Andrew K, Smith II, Leon M, De Lucca, Indawati, Wexler, Ruth R, Pinto, Donald J.P, Zhu, Yeheng
Year of Publication 28.10.2021
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Year of Publication 28.10.2021
Patent