Preparation and Structure−Activity Relationship of Novel P1/P1‘-Substituted Cyclic Urea-Based Human Immunodeficiency Virus Type-1 Protease Inhibitors
Nugiel, David A, Jacobs, Kim, Worley, Tabitha, Patel, Mona, Kaltenbach, Robert F, Meyer, Dayton T, Jadhav, Prabhakar K, De Lucca, George V, Smyser, Thomas E, Klabe, Ronald M, Bacheler, Lee T, Rayner, Marlene M, Seitz, Steven P
Published in Journal of medicinal chemistry (24.05.1996)
Published in Journal of medicinal chemistry (24.05.1996)
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Does a diol cyclic urea inhibitor of HIV-1 protease bind tighter than its corresponding alcohol form? A study by free energy perturbation and continuum electrostatics calculations
Wang, L, Duan, Y, Stouten, P, De Lucca, G V, Klabe, R M, Kollman, P A
Published in Journal of computer-aided molecular design (01.02.2001)
Published in Journal of computer-aided molecular design (01.02.2001)
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Design, Synthesis, and Evaluation of Tetrahydropyrimidinones as an Example of a General Approach to Nonpeptide HIV Protease Inhibitors
De Lucca, George V, Liang, Jing, Aldrich, Paul E, Calabrese, Joe, Cordova, Beverly, Klabe, Ronald M, Rayner, Marlene M, Chang, Chong-Hwan
Published in Journal of medicinal chemistry (23.05.1997)
Published in Journal of medicinal chemistry (23.05.1997)
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Nonsymmetric P2/P2‘ Cyclic Urea HIV Protease Inhibitors. Structure−Activity Relationship, Bioavailability, and Resistance Profile of Monoindazole-Substituted P2 Analogues
De Lucca, George V, Kim, Ui T, Liang, Jing, Cordova, Beverly, Klabe, Ronald M, Garber, Sena, Bacheler, Lee T, Lam, Gilbert N, Wright, Matthew R, Logue, Kelly A, Erickson-Viitanen, Susan, Ko, Soo S, Trainor, George L
Published in Journal of medicinal chemistry (18.06.1998)
Published in Journal of medicinal chemistry (18.06.1998)
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De novo design and discovery of cyclic HIV protease inhibitors capable of displacing the active-site structural water molecule
De Lucca, G V, Jadhav, P K, Waltermire, R E, Aungst, B J, Erickson-Viitanen, S, Lam, P Y
Published in Pharmaceutical biotechnology (1998)
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Published in Pharmaceutical biotechnology (1998)
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Protein β-turn mimetics I. Design, synthesis, and evaluation in model cyclic peptides
Ripka, W.C., De Lucca, G.V., Bach, A.C., Pottorf, R.S., Blaney, J.M.
Published in Tetrahedron (23.03.1993)
Published in Tetrahedron (23.03.1993)
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Discovery of CC Chemokine Receptor-3 (CCR3) Antagonists with Picomolar Potency
De Lucca, George V, Kim, Ui Tae, Vargo, Brian J, Duncia, John V, Santella, Joseph B, Gardner, Daniel S, Zheng, Changsheng, Liauw, Ann, Wang, Zhang, Emmett, George, Wacker, Dean A, Welch, Patricia K, Covington, Maryanne, Stowell, Nicole C, Wadman, Eric A, Das, Anuk M, Davies, Paul, Yeleswaram, Swamy, Graden, Danielle M, Solomon, Kimberly A, Newton, Robert C, Trainor, George L, Decicco, Carl P, Ko, Soo. S
Published in Journal of medicinal chemistry (24.03.2005)
Published in Journal of medicinal chemistry (24.03.2005)
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Discovery and Structure−Activity Relationship of N-(Ureidoalkyl)-Benzyl-Piperidines As Potent Small Molecule CC Chemokine Receptor-3 (CCR3) Antagonists
De Lucca, George V, Kim, Ui T, Johnson, Curt, Vargo, Brian J, Welch, Patricia K, Covington, Maryanne, Davies, Paul, Solomon, Kimberly A, Newton, Robert C, Trainor, George L, Decicco, Carl P, Ko, Soo S
Published in Journal of medicinal chemistry (15.08.2002)
Published in Journal of medicinal chemistry (15.08.2002)
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Protein β-turn mimetics II: Design, synthesis, and evaluation in the cyclic peptide gramicidin S
Ripka, W.C., De Lucca, G.V., Bach, A.C., Pottorf, R.S., Blaney, J.M.
Published in Tetrahedron (23.03.1993)
Published in Tetrahedron (23.03.1993)
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Calculated and Experimental Low-Energy Conformations of Cyclic Urea HIV Protease Inhibitors
Hodge, C. Nicholas, Lam, Patrick Y. S, Eyermann, Charles J, Jadhav, Prabhakar K, Ru, Y, Fernandez, Christina H, De Lucca, George V, Chang, Chong-Hwan, Kaltenbach, Robert F, Holler, Edward R, Woerner, Francis, Daneker, Wayne F, Emmett, George, Calabrese, Joseph C, Aldrich, Paul E
Published in Journal of the American Chemical Society (20.05.1998)
Published in Journal of the American Chemical Society (20.05.1998)
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