Genetic and Molecular Basis of Heterogeneous NK Cell Responses against Acute Leukemia
Makanga, Dhon Roméo, Da Rin de Lorenzo, Francesca, David, Gaëlle, Willem, Catherine, Dubreuil, Léa, Legrand, Nolwenn, Guillaume, Thierry, Peterlin, Pierre, Lebourgeois, Amandine, Béné, Marie Christine, Garnier, Alice, Chevallier, Patrice, Gendzekhadze, Ketevan, Cesbron, Anne, Gagne, Katia, Clemenceau, Béatrice, Retière, Christelle
Published in Cancers (01.07.2020)
Published in Cancers (01.07.2020)
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Journal Article
Characterization of the SOD1-G93A mouse model of Amyotrophic lateral sclerosis and a promising treatment for the disease
Santamonica, Sara Figuerola, Lorenzo, Francesca De, Sendtner, Michael, Saarma, Mart, Voutilainen, Merja
Published in Proceedings for Annual Meeting of The Japanese Pharmacological Society (2018)
Published in Proceedings for Annual Meeting of The Japanese Pharmacological Society (2018)
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Journal Article
Novel Small‐Molecular Ligands for Prolyl Oligopeptidase to Combat Tauopathies
Eteläinen, Tony, Pätsi, Henri, Uhari‐Väänänen, Johanna, Aikkila, Hannes, Cui, Hengjing, De Lorenzo, Francesca, Kilpeläinen, Tommi, Julku, Ulrika, Wallén, Erik A.A., Myöhänen, Timo T
Published in Alzheimer's & dementia (01.12.2023)
Published in Alzheimer's & dementia (01.12.2023)
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Journal Article
CDNF rescues motor neurons in models of amyotrophic lateral sclerosis by targeting endoplasmic reticulum stress
De Lorenzo, Francesca, Lüningschrör, Patrick, Nam, Jinhan, Beckett, Liam, Pilotto, Federica, Galli, Emilia, Lindholm, Päivi, Rüdt von Collenberg, Cora, Mungwa, Simon Tii, Jablonka, Sibylle, Kauder, Julia, Thau-Habermann, Nadine, Petri, Susanne, Lindholm, Dan, Saxena, Smita, Sendtner, Michael, Saarma, Mart, Voutilainen, Merja H
Published in Brain (London, England : 1878) (01.09.2023)
Published in Brain (London, England : 1878) (01.09.2023)
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Removal of proteinase K resistant αSyn species does not correlate with cell survival in a virus vector-based Parkinson's disease mouse model
Eteläinen, Tony S., Kilpeläinen, Tommi P., Ignatius, Adele, Auno, Samuli, De Lorenzo, Francesca, Uhari-Väänänen, Johanna K., Julku, Ulrika H., Myöhänen, Timo T.
Published in Neuropharmacology (01.11.2022)
Published in Neuropharmacology (01.11.2022)
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5‑Aminothiazoles Reveal a New Ligand-Binding Site on Prolyl Oligopeptidase Which is Important for Modulation of Its Protein–Protein Interaction-Derived Functions
Pätsi, Henri T., Kilpeläinen, Tommi P., Jumppanen, Mikael, Uhari-Väänänen, Johanna, Wielendaele, Pieter Van, De Lorenzo, Francesca, Cui, Hengjing, Auno, Samuli, Saharinen, Janne, Seppälä, Erin, Sipari, Nina, Savinainen, Juha, De Meester, Ingrid, Lambeir, Anne-Marie, Lahtela-Kakkonen, Maija, Myöhänen, Timo T., Wallén, Erik A. A.
Published in Journal of medicinal chemistry (11.04.2024)
Published in Journal of medicinal chemistry (11.04.2024)
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Journal Article
A prolyl oligopeptidase inhibitor reduces tau pathology in cellular models and in mice with tauopathy
Eteläinen, Tony S, Silva, M Catarina, Uhari-Väänänen, Johanna K, De Lorenzo, Francesca, Jäntti, Maria H, Cui, Hengjing, Chavero-Pieres, Marta, Kilpeläinen, Tommi, Mechtler, Christina, Svarcbahs, Reinis, Seppälä, Erin, Savinainen, Juha R, Puris, Elena, Fricker, Gert, Gynther, Mikko, Julku, Ulrika H, Huttunen, Henri J, Haggarty, Stephen J, Myöhänen, Timo T
Published in Science translational medicine (12.04.2023)
Published in Science translational medicine (12.04.2023)
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Journal Article
Evidence for an Additive Neurorestorative Effect of Simultaneously Administered CDNF and GDNF in Hemiparkinsonian Rats: Implications for Different Mechanism of Action
Voutilainen, Merja H, De Lorenzo, Francesca, Stepanova, Polina, Bäck, Susanne, Yu, Li-Ying, Lindholm, Päivi, Pörsti, Eeva, Saarma, Mart, Männistö, Pekka T, Tuominen, Raimo K
Published in eNeuro (01.01.2017)
Published in eNeuro (01.01.2017)
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Journal Article
CDNF rescues motor neurons in three animal models of ALS by targeting ER stress
De Lorenzo, Francesca, Lüningschrör, Patrick, Nam, Jinhan, Pilotto, Federica, Galli, Emilia, Lindholm, Päivi, Cora Rüdt Von Collenberg, Mungwa, Simon Tii, Jablonka, Sibylle, Kauder, Julia, Petri, Susanne, Lindholm, Dan, Saxena, Smita, Sendtner, Michael, Saarma, Mart, Voutilainen, Merja H
Published in bioRxiv (16.09.2020)
Published in bioRxiv (16.09.2020)
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